Week 5 is here on the college gridiron after a week 4 that saw the top 10 have several close calls (Oklahoma, Penn State, USC) and one surprise upset that saw then #6 Oklahoma State lose to an underrated TCU squad 44-31.

This week brings us several quality matchups for both our viewing and betting pleasure as conference play is in full effect.

Video: Uncle Lou’s Week 5 College Football Game Previews:

USC at Washington State: Friday 9/29 at 10:30 pm ET

The week kicks off on Friday in the Pac 12 where Washington State will be looking to pull the upset over the 5th ranked Trojans of USC. The Cougars are coming off a 45-7 thumping over Nevada on Saturday while USC is coming off a hard-fought 30-20 victory over Cal.

Heisman candidate Sam Darnold will look to get back on track after a lackluster effort versus Cal last week when the Golden Bears were able to force him from the pocket numerous times. The Cougars have a quarterback of their own in Luke Falk, who's coming off a monster effort versus Nevada where he threw for 478 yards and 5 touchdowns.

USC opened as a -6 point favorite but previous lackluster efforts by the Trojans led bettors to quickly push the line down to its current -3.5. The total sits at 65 as many are looking for an aerial assault from the big time QBs. Can USC finally put it together on the road and show everyone why they carry a #5 ranking in the polls? Do their scores and odds hold merit?

Georgia Bulldogs at Tennessee Volunteers: Saturday 9/30 at 3:30 pm ET

Our next game features the red-hot Bulldogs heading to Knoxville to pay a visit to the Volunteers in this SEC East matchup. Georgia enters the contest on fire having throttled the previously undefeated and ranked Bulldogs from Mississippi State 31-3. While Tennessee has struggled this season barely squeezing out a victory over the previously winless UMass Minutemen 17-13 at home after previously losing on a hail-mary to the Florida Gators.

Georgia opened as a -6.5 point favorite but was quickly bet to -7.5 even touching -8 a few times over the week. The total currently sits at 47.5 which is just a half point off the opening 48. Be careful going overboard on this game at the window. While it looks like a mismatch on paper, this is still a long time SEC East rivalry game that you have to think the Volunteers will be playing with intensity. Plus, Butch Jones seat might be getting a little warm in Knoxville and a win over a top 10 opponent could go a long way in appeasing an uneasy fan base.

Also Read: The SEC Least | Power 5’s Weakest Division?

Clemson at Virginia Tech: Saturday 9/30 at 8:00 pm ET

Our final game and my personal favorite has the #2 ranked Clemson Tigers traveling to Blacksburg to take on the #12 ranked Virginia Tech Hokies. Virginia Tech is coming in off a 38-0 victory over an overmatched Old Dominion team while Clemson enters the contest off a 34-7 thumping of Boston College. Clemson is continuing their early season resume building as this will be the third ranked opponent they have faced in the past four weeks with previous wins over Auburn and Louisville to put away for later.

Clemson opened as a -7 point favorite and currently sits at -7.5 to -8 at various offshore shops. The total opened at 51.5 and has not moved as of today. Clemson has looked dominant this season and Virginia Tech will need to execute a nearly flawless game plan in order to stay with this Clemson team. They are a monster on defense with an offense that appears to get better each week.

Another week filled with big-time matchups as conference play is going full speed. The ACC, the SEC, the Pac 12 all with a little something to bring to the table for our weekend enjoyment. And not to mention this is college football, so it's only a matter of time before we get our first week 5 upset alert. Good luck on the week and let's hope all your tickets are cashing.

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