2023 March Madness Sweet 16 Odds and Picks

After four days of exciting college basketball action, we’re now down to 16 teams in the March Madness tournament. The Sweet Sixteen round will feature four games on Thursday and four games on Friday.

March Madness Betting Sites

Let’s jump into the moneyline odds and I’ll also predict the winner of all eight match-ups.

Michigan State vs. Kansas State Predictions

Odds to Win: Michigan State (-130) vs. Kansas State (+110)

#7 MSU defeated #10 USC and #2 Marquette due to strong defensive play. #3 KSU looked good in a win against #6 Kentucky. Markquis Nowell had 27 points and 9 assists in the win over Kentucky.

Best Bet: Kansas State to Win (+110)

March Madness Odds

Arkansas vs. UConn Predictions

Odds to Win: Arkansas (+150) vs. UConn (-175)

#8 Arkansas just knocked out #1 Kansas in a thriller. #4 UConn had blowout wins against #13 Iona and #5 Saint Mary’s. Adama Sanogo has 52 points and 21 rebounds in the Huskies first two games.

Best Bet: UConn to Win (-175)

Florida Atlantic vs. Tennessee Predictions

Odds to Win: Florida Atlantic (+200) vs. Tennessee (-240)

#4 Tennessee are coming off a double-digit win against #5 Duke. #9 FAU have wins against #8 Memphis and #16 Fairleigh Dickinson. The Volunteers defense has been dominant and they’ll cruise to a win.

Best Bet: Tennessee to Win (-240)

Best Sports Handicappers

Gonzaga vs. UCLA Predictions

Odds to Win: Gonzaga (+115) vs. UCLA (-135)

#3 Gonzaga barely survived against #6 TCU. #2 UCLA just eliminated #7 Northwestern. Drew Timme has 49 points for the Zags in the tourney, but UCLA have the depth and size to frustrate Gonzaga.

Best Bet: UCLA to Win (-135)

San Diego State vs. Alabama Predictions

Odds to Win: San Diego State (+280) vs. Alabama (-340)

#5 SDSU have had an easy path to the Sweet 16. #1 Alabama have won both of their games by 20+ points. The Aztecs will try to slow the game down and may cover ATS, but they won’t win the game.

Best Bet: Alabama to Win (-340)

March Madness Picks

Miami vs. Houston Predictions

Odds to Win: Miami (+240) vs. Houston (-285)

#5 Miami just dominated #4 Indiana, scoring 85 points in the win. #1 Houston are coming off a win against #9 Auburn. Miami are scoring 79.1 PPG (18th) and can keep up with the Cougars.

Best Bet: Miami to Win (+240)

Princeton vs. Creighton Predictions

Odds to Win: Princeton (+400) vs. Creighton (-500)

#15 Princeton have made the Sweet 16 for the first time since 1967. They defeated #1 Arizona and #7 Missouri. #6 Creighton just eliminated #3 Baylor and are strong at all five positions.

Best Bet: Creighton to Win (-500)

PPH Software

Xavier vs. Texas Predictions

Odds to Win: Xavier (+160) vs. Texas (-190)

#3 Xavier had an easy path to the Sweet 16 with wins against #14 Kennesaw State and #11 Pittsburgh. #2 Texas just defeated a strong #10 Penn State team. This will be close, but I’m betting on Texas.

Best Bet: Texas to Win (-190)