Running back Ricky Person Jr. rushed for two touchdowns and threw for another one as host North Carolina State pulled out a 45-42 season-opening victory against Wake Forest on Saturday night in Raleigh, N.C.
D'Eriq King passed for 325 yards and three touchdowns, and Cam'Ron Harris ran for 134 yards as the 17th-ranked Miami Hurricanes defeated the 18th-ranked Louisville Cardinals 47-34 in an ACC game on Saturday night.
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Shane Buechele passed for 344 yards and four touchdowns, and added another score on the ground, as the visiting SMU Mustangs roared to an early lead and dominated North Texas 65-35 on Saturday in Denton, Texas.
The No. 1 Clemson Tigers scored on six straight possessions to open the game and improved to 2-0 with a 49-0 rout of The Citadel on Saturday at Clemson's Memorial Stadium.
Brenden Knox rushed 28 times for 138 yards and a touchdown as Marshall's running game outperformed the more-hyped ground attack of No. 24 Appalachian State in a 17-7 victory on Saturday in Huntington, W. Va.
Sophomore Dillon Gabriel tied a career high with four touchdown passes, two each to wide receivers Marlon Williams and Tre Nixon, and No. 14 Central Florida won its 2020 opener 49-21 over Georgia Tech Saturday in Atlanta.
Seventh-ranked Notre Dame capitalized on a series of special teams blunders and overwhelmed South Florida on defense to cruise to a 52-0 rout Saturday at Notre Dame Stadium.
Gerrid Doaks scored four touchdowns Saturday as No. 13 Cincinnati opened its college football season with an easy 55-20 romp over Austin Peay at Nippert Stadium in Cincinnati.
Phil Jurkovec threw two touchdown passes in his first game for Boston College in a 26-6 season-opening victory at Duke on Saturday afternoon in Durham, N.C.
Kenny Pickett passed for two touchdowns and ran for another to lead No. 25 Pittsburgh to a 21-10 victory over visiting Syracuse in ACC play on Saturday.
Third-string quarterback Shane Illingworth, a four-star true freshman, came off the bench to spark No. 11 Oklahoma State to a 16-7 victory over visiting Tulsa on Saturday in a season-opening nonconference game for both teams in Stillwater, Okla.
Bijan Nichols kicked a 33-yard field goal with no time remaining as visiting Navy overcame a 24-point deficit to post a 27-24 victory over Tulane on Saturday in the American Athletic Conference opener for both teams.
Senior Elijah Mitchell scored on a 12-yard run on his fourth carry in overtime to give No. 19 Louisiana a 34-31 victory over Georgia State in a Sun Belt Conference game Saturday in Atlanta.
Redshirt freshman Grayson McCall accounted for five touchdowns Saturday in his college debut as Coastal Carolina capitalized on three takeaways and upset Kansas 38-23 at Lawrence, Kan.
Micale Cunningham passed for 343 yards with three touchdowns to lead Louisville to a 35-21 season-opening win over Western Kentucky at Cardinal Stadium.
Texas quarterback Sam Ehlinger threw for 426 yards and touchdowns to five different receivers, all in the first half, as the No. 14 Longhorns stampeded past visiting UTEP 59-3 on Saturday in Austin, Texas.
Alan Bowman threw for 430 yards and two touchdowns Saturday night as host Texas Tech barely held off FCS opponent Houston Baptist 35-33 win in the Red Raiders' season opener in Lubbock, Texas.
Trevor Lawrence ran for two touchdowns and threw for another as No. 1 Clemson opened the season with authority, drilling host Wake Forest 37-13 on Saturday night at Truist Field in Winston-Salem, N.C.
Cameron Carroll had two of Tulane's four rushing touchdowns as the Green Wave scored the final 21 points and defeated host South Alabama 27-24 in a nonconference game Saturday night.
The Jeff Scott era at the University of South Florida began on a positive note as the host Bulls defeated The Citadel 27-6 in their regular season opener on Saturday night at Raymond James Stadium.