The Boston Red Sox will have a decided advantage on the mound in their quest to finish off a three-game sweep at the Baltimore Orioles on Wednesday. Star lefty Chris Sale, who limited the Orioles to two hits while striking out eight in five innings earlier in the year, goes for the Red Sox as they aim for an eighth consecutive victory at Camden Yards.

Toronto Blue Jays vs. Tampa Bay Rays Preview and Predictions 06-13-2018

Baltimore originally planned to start veteran Andrew Cashner but he was placed on the 10-day disabled list prior to Tuesday's game with back soreness, forcing the club to turn to Yefry Ramirez for his major-league debut opposite Sale. Andrew Benintendi homered and forced in a run with a walk to help Boston pick up a 6-4 victory Tuesday night, giving the club a 23-11 record both at home and on the road. Mookie Betts, the top vote-getter in current All-Star balloting, returned from an abdominal strain in the series opener before sitting out the second game, but is expected to return for this one. The Orioles got Manny Machado back Tuesday from a one-game absence but they left 13 runners on base while losing a sixth consecutive game.

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TV: 3:05 p.m. ET, MLB Network, NESN (Boston), MASN2 (Baltimore)

PITCHING MATCHUP: Red Sox LH Chris Sale (5-4, 2.83 ERA) vs. Orioles RH Yefry Ramirez (NR)

Sale has lost three straight starts but he was solid in the most recent one, tossing eight innings of one-run ball while striking out 10 in a 1-0 loss to the Chicago White Sox. He has a 2.68 ERA in eight road starts while limiting opponents to a .188 average. The six-time All-Star is 4-1 with a 2.29 ERA in nine career games (six starts) at Camden Yards but will need to be careful with Machado, who is 6-for-16 with a home run and two doubles against Sale.

Ramirez is 3-4 with a 4.33 ERA in 12 starts for Triple-A Norfolk, recording 63 strikeouts and allowing 53 hits in 60 1/3 innings. The 24-year-old was with Baltimore for one day in April but did not appear in a game. He is 38-30 with a 3.55 mark in seven seasons in the minors, going 15-3 at the Double-A level last year while splitting the season between the New York Yankees and Baltimore systems.

Video: Condensed Game: BOS@BAL - 6/12/18


1. Benintendi is batting .412 with three homers and 13 RBIs in nine games against Baltimore this year.

2. Orioles LHP Zach Britton, who had 135 saves over the previous four years, made his season debut Tuesday after recovering from Achilles surgery.

3. The Red Sox drew a season-high 10 walks Tuesday.

PREDICTION: Red Sox 7, Orioles 3