Los Angeles Chargers vs. Arizona Cardinals Pick & Prediction NOVEMBER 27th 2022

Stadium: University of Phoenix Stadium Glendale
Logo Los Angeles Chargers
Logo Arizona Cardinals

47.5o -105



The Los Angeles Chargers are 5-5 with a 3-2 record on the road. This weekend, they’ll face the Arizona Cardinals, who have a 1-5 record at home. The Chargers have lost three of their last five games. This includes a recent 30-27 loss to the Kansas City Chiefs. After losing two games in a row, facing the Cardinals might be a tough task for the Chargers.

The Arizona Cardinals have lost three of their last five games. Their most recent loss was a 38-10 loss to the San Francisco 49ers last week. With an overall record of 4-7, things aren’t looking good for the Cardinals. It’ll take a lot to get back on track, but a win over the Chargers could be what they need.

Chargers vs. Cardinals Odds


MONEY LINE: Chargers (-156) vs. Cardinals (+132)

SPREAD: Chargers -3 (-105) vs. Cardinals +3 (-115)

GAME TOTAL: Over 48.5 (-110) vs. Under 48.5 (-110)

Chargers vs. Cardinals Preview, Trends and Stats

The Los Angeles Chargers come into this game as three-point favorites. Although the spread isn’t large, it’s definitely something to keep in mind. This season, the Chargers have gone 7-3 against the spread (ATS), which is an impressive record.

As a team, the Chargers have a 5-5 record, so their ATS record is pretty shocking. They have one of the best passing offenses in the league, averaging 263.8 passing yards per game. The biggest problem the Chargers have is on the defensive side of the ball.

This season, they’ve allowed an average of 25.8 points per game. Ranking as one of the worst teams in this category, the Chargers are 29th in the NFL. They’re playing a pretty good offense this week, especially with Kyler Murray back on the field.

Ranked No. 3 in the NFC West, the Arizona Cardinals have taken a step back from last year. Kyler Murray has missed a few games though, so their losses could be attributed to that. However, there is no excuse for their defense ranking 31st in the NFL.

On average, the Cardinals are giving up 26.9 points per game. As an offense, they’re putting up 21.8 points per game and rank 18th in the NFL. The San Francisco 49ers ran all over them last week, putting up a total of 38 points. Keep in mind, Murray didn’t play in this game either.

Chargers vs. Cardinals Picks

In our opinion, this game is pretty clear to us; the Chargers should be able to pull off a win. The question then becomes whether they can cover the spread. This season, the Arizona Cardinals have a 5-6 record against the spread. When compared to the Chargers record, the pick becomes clearer.

We’d recommend taking the Los Angeles Chargers at -3 over the Arizona Cardinals. The Chargers have covered the spread in five straight road games. They also have a 2-1 record in their last three games against Arizona.

Final Score: 29-24 (Chargers)


1. The total has gone OVER in eleven of the LA Chargers last 16 games.

2. The Chargers are 5-2 against the spread in their last seven games.

3. The Cardinals have a 2-4 record against the spread in their last six games.

Best Bet: Chargers -3 (-105) and Over 48.5 (-110)

Los Angeles Chargers
Arizona Cardinals