San Francisco 49ers are 2-0 in 2026, 1-0 at home, 0-0 away and 1-0 at a neutral site, after Week 2. The 49ers beat the Rams 27-7 at a neutral site in Week 1 and beat the Dolphins 35-13 at home in Week 2.

The next 49ers game

The 49ers host the Cardinals in Week 3, Sun 27 Sep, 4:05 PM ET. Our full call on it is in the Arizona Cardinals at San Francisco 49ers prediction.

San Francisco 49ers 2026 schedule

Every game of the regular season, in order, with the bye week. Kickoff times are Eastern.

Week	Kickoff	Home or away	Opponent
Week 1	Thu 10 Sep, 8:35 PM ET	Neutral site	Los Angeles Rams
Week 2	Sun 20 Sep, 4:25 PM ET	Home	Miami Dolphins
Week 3	Sun 27 Sep, 4:05 PM ET	Home	Arizona Cardinals
Week 4	Sun 4 Oct, 4:25 PM ET	Home	Denver Broncos
Week 5	Sun 11 Oct, 4:25 PM ET	Away	Seattle Seahawks
Week 6	Mon 19 Oct, 8:15 PM ET	Home	Washington Commanders
Week 7	Sun 25 Oct, 1:00 PM ET	Away	Atlanta Falcons
Week 8			Bye week
Week 9	Sun 8 Nov, 4:05 PM ET	Home	Las Vegas Raiders
Week 10	Sun 15 Nov, 4:25 PM ET	Away	Dallas Cowboys
Week 11	Sun 22 Nov, 8:20 PM ET	Neutral site	Minnesota Vikings
Week 12	Sun 29 Nov, 4:25 PM ET	Home	Seattle Seahawks
Week 13	Sun 6 Dec, 1:00 PM ET	Away	New York Giants
Week 14	Sun 13 Dec, 4:25 PM ET	Home	Los Angeles Rams
Week 15	Thu 17 Dec, 8:15 PM ET	Away	Los Angeles Chargers
Week 16	Sun 27 Dec, 4:25 PM ET	Away	Kansas City Chiefs
Week 17	Sun 3 Jan, 8:20 PM ET	Home	Philadelphia Eagles
Week 18	Not set yet	Away	Arizona Cardinals

The 49ers roster

Kyle Shanahan is the head coach. ESPN lists 26 players on offense, 25 on defense and 3 on special teams, read 25 September 2026. The quarterbacks on the roster are Mac Jones (#10), Brock Purdy (#13) and Kurtis Rourke (#14).

San Francisco 49ers in 2025

The 49ers finished the 2025 regular season 12-5, 5-3 at home and 7-2 on the road. They scored 437 points and allowed 371. Their biggest win was 48-27 away at the Colts, and their heaviest defeat 42-26 at home to the Rams. In the playoffs they beat the Eagles 23-19 in the Wild Card round and lost to the Seahawks 41-6 in the Divisional round.

Where to go next

This page is the record: schedule, results and roster. Our call on a game is written separately, on the Week 3 page and every NFL prediction.