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Charlotte FC (16-11-2, 50 points) are riding an eight-match winning streak and can clinch a playoff berth Saturday with a win and a New York Red Bulls loss. A ninth consecutive victory would tie the all-time MLS record for most wins in a row (non-shootout era). Inter Miami (13-5-7, 46 points) enter sixth in the East, but still have multiple games in hand compared to the clubs above them. That means they can climb the standings, but it must start here — against a red-hot Charlotte team in front of a likely sold-out crowd of 35,000. Coach Dean Smith will miss the match due to suspension, but Charlotte remain confident. Messi put it simply last week: Main Pick: Charlotte FC

FC Cincinnati (16-9-4, 52 points) host Nashville SC on Saturday with a chance to secure an MLS Cup playoff berth. Despite back-to-back 1-0 home defeats and a four-week scoring drought, Cincinnati sit second in the Eastern Conference. A victory here would end that slump and guarantee postseason soccer. Nashville (15-9-5, 50 points) are right behind them in the table. Led by Sam Surridge (20 goals) and Hany Mukhtar (14 goals), they boast one of the league’s most dangerous attacking duos — and still have eyes on climbing into a top-three seed. Main Pick: FC Cincinnati Moneyline (+115)Projected Final Score: Cincinnati 2, Nashville 1 Check more MLS projections at our Soccer Predictions Hub. Best Bet: Over 2.5 Goals (-110)Confidence: ★★★★☆

The Columbus Crew (12-6-10, 46 points) look to stay above the Eastern Conference playoff line when they visit Atlanta United (5-12-11, 26 points) on Saturday. Columbus has not won since July 19 but remains in seventh place, while Atlanta risks elimination if they fail to win. Columbus won the reverse fixture 3-1 in June, with Jacen Russell-Rose netting a brace. Atlanta coach Ronny Deila admitted that match was his side’s “worst performance of the season” — making this a chance at redemption. Main Pick: Columbus Crew Moneyline (+125)Projected Final Score: Crew 2, Atlanta 1 Get sharper breakdowns at our MLS Betting Predictions hub. Best Bet: Columbus Crew ML (+125)Confidence: ★★★★☆

The Portland Timbers (10-9-9, 39 points) are clinging to the seventh spot in the Western Conference playoff picture but have gone winless in four straight matches. On Saturday night, they host the New York Red Bulls (11-11-7, 40 points), who are fighting for an Eastern Conference playoff berth but haven’t won on the road since May 24. Both teams are desperate: Portland is just three points clear of ninth-place Colorado, while New York sits two points behind Chicago for the final playoff spot in the East. Main Pick: Draw (+240)Projected Final Score: Timbers 1, Red Bulls 1 Get sharper calls like this at our MLS Betting Predictions hub. Best Bet: Under 2.5 Goals (-110)Confidence: ★★★★☆