MLB Predictions

At ScoresandStats, we cover the MLB season every day, providing previews, predictions and matchup breakdowns in our blog section. Every user has access to these picks and previews, regardless of subscription status.

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MLB predictions on Scores and Stats cover selected games every day. Our staff writers, including Sal Lombardi, Ethan Cole and Mario Vega, pick the games and publish each prediction on its own page, dated for the day it is played.

The grid below lists the predictions that are up now. With the regular season ending on Sunday, 27 September 2026, this page also gives you the division races as they stand, last year’s World Series and a link to every team.

Baseball MLB Previews and Predictions Every game on the board, priced and picked before it starts

Minnesota Twins vs Texas Rangers
Minnesota Twins Minnesota Twins
VS
Texas Rangers Texas Rangers
Sep 25, 8:11 PM ET
SPREADTOTALML
1.50-156
O 7.50+104
+108
-1.5+130
U 7.50-128
-127
PREVIEW ANGLE

Texas Rangers vs Minnesota Twins Picks, Predictions and Odds: What matters before Saturday’s middle game? Texas Rangers visits Minnesota Twins on Saturday,

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San Diego Padres vs Arizona Diamondbacks
San Diego Padres San Diego Padres
VS
Arizona Diamondbacks Arizona Diamondbacks
Sep 25, 9:41 PM ET
SPREADTOTALML
-1.50+158
O 7.50-115
-133
+1.5-192
U 7.50-105
+114
PREVIEW ANGLE

Arizona Diamondbacks vs San Diego Padres Picks, Predictions and Odds: What matters before Saturday’s middle game? Arizona Diamondbacks visits San Diego Padres

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Athletics vs Houston Astros
Athletics Athletics
VS
Houston Astros Houston Astros
Sep 25, 9:41 PM ET
SPREADTOTALML
1.50-110
O 9.50+104
+152
-1.5-110
U 9.50-128
-179
PREVIEW ANGLE

Houston Astros vs Athletics Picks, Predictions and Odds: What matters before Saturday’s middle game? Houston Astros visits Athletics on Saturday, September 26,

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Seattle Mariners vs Los Angeles Angels
Seattle Mariners Seattle Mariners
VS
Los Angeles Angels Los Angeles Angels
Sep 25, 10:11 PM ET
SPREADTOTALML
1.50-227
O 6.50-115
-118
-1.5+184
U 6.50-105
+100
PREVIEW ANGLE

Los Angeles Angels vs Seattle Mariners Picks, Predictions and Odds: What matters before Saturday’s middle game? Los Angeles Angels visits Seattle Mariners

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San Francisco Giants vs Los Angeles Dodgers
San Francisco Giants San Francisco Giants
VS
Los Angeles Dodgers Los Angeles Dodgers
Sep 25, 10:16 PM ET
SPREADTOTALML
1.50+150
O 7.50-114
+265
-1.5-182
U 7.50-106
-333
PREVIEW ANGLE

Los Angeles Dodgers vs San Francisco Giants Picks, Predictions and Odds: What matters before Saturday’s middle game? Los Angeles Dodgers visits San

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Baltimore Orioles vs New York Yankees
Odds coming soon
PREVIEW ANGLE

Baltimore Orioles vs New York Yankees Picks, Predictions and Odds: What matters before Saturday’s middle game? Baltimore Orioles visits New York Yankees

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Recaps What the market did, and how the call held against the result

Kansas City Royals vs Cleveland Guardians
Kansas City Royals Kansas City Royals
VS
Cleveland Guardians Cleveland Guardians
Sep 25, 7:41 PM ET
SPREADTOTALML
1.50-145
O 7.50+106
+120
-1.5+120
U 7.50-130
-143
PREVIEW ANGLE

Cleveland Guardians vs Kansas City Royals Picks, Predictions and Odds: What matters before Saturday’s middle game? Cleveland Guardians visits Kansas City Royals

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Milwaukee Brewers vs St. Louis Cardinals
Milwaukee Brewers Milwaukee Brewers
VS
St. Louis Cardinals St. Louis Cardinals
Sep 25, 7:41 PM ET
SPREADTOTALML
-1.50+120
O 7.50-118
-189
+1.5-145
U 7.50-104
+158
PREVIEW ANGLE

St. Louis Cardinals vs Milwaukee Brewers Picks, Predictions and Odds: Which edge survives the current price? The St. Louis Cardinals visit the

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Chicago White Sox vs Colorado Rockies
Chicago White Sox Chicago White Sox
VS
Colorado Rockies Colorado Rockies
Sep 25, 7:40 PM ET
SPREADTOTALML
-1.50-114
O 8.50-105
-250
+1.5-105
U 8.50-115
+205
PREVIEW ANGLE

Colorado Rockies vs Chicago White Sox Picks, Predictions and Odds: What matters before Saturday’s middle game? Colorado Rockies visits Chicago White Sox

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Miami Marlins vs Atlanta Braves
Miami Marlins Miami Marlins
VS
Atlanta Braves Atlanta Braves
Sep 25, 7:11 PM ET
SPREADTOTALML
1.50-179
O 8.50+104
+100
-1.5+146
U 8.50-128
-118
PREVIEW ANGLE

Atlanta Braves vs Miami Marlins Picks, Predictions and Odds: What matters before Saturday’s middle game? Atlanta Braves visits Miami Marlins on Saturday,

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Detroit Tigers vs Pittsburgh Pirates
Detroit Tigers Detroit Tigers
VS
Pittsburgh Pirates Pittsburgh Pirates
Sep 25, 7:08 PM ET
SPREADTOTALML
1.50-200
O 8.00-105
-115
-1.5+160
U 8.00-115
-105
PREVIEW ANGLE

Pittsburgh Pirates vs Detroit Tigers Picks, Predictions and Odds: What matters before Saturday’s middle game? Pittsburgh Pirates visits Detroit Tigers on Saturday,

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Toronto Blue Jays vs Cincinnati Reds
Toronto Blue Jays Toronto Blue Jays
VS
Cincinnati Reds Cincinnati Reds
Sep 25, 7:08 PM ET
SPREADTOTALML
-1.50+146
O 7.50-115
-154
+1.5-175
U 7.50-105
+130
PREVIEW ANGLE

Cincinnati Reds vs Toronto Blue Jays Picks, Predictions and Odds: What matters before Saturday’s middle game? Cincinnati Reds visits Toronto Blue Jays

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This week’s MLB predictions

Every MLB prediction for a game still to be played, in date order, listed 25 September 2026.

Game datePrediction
Fri 25 SepArizona Diamondbacks vs San Diego Padres Picks, Predictions and Odds
Fri 25 SepBaltimore Orioles vs New York Yankees Picks, Predictions and Odds
Fri 25 SepCincinnati Reds vs Toronto Blue Jays Picks, Predictions and Odds
Fri 25 SepTexas Rangers vs Minnesota Twins Picks, Predictions and Odds
Fri 25 SepColorado Rockies vs Chicago White Sox Picks, Predictions and Odds
Fri 25 SepLos Angeles Angels vs Seattle Mariners Picks, Predictions and Odds
Fri 25 SepPittsburgh Pirates vs Detroit Tigers Picks, Predictions and Odds
Fri 25 SepSt. Louis Cardinals vs Milwaukee Brewers Picks, Predictions and Odds
Fri 25 SepAtlanta Braves vs Miami Marlins Picks, Predictions and Odds
Fri 25 SepChicago Cubs vs Boston Red Sox Picks, Predictions and Odds
Fri 25 SepCleveland Guardians vs Kansas City Royals Picks, Predictions and Odds
Fri 25 SepHouston Astros vs Athletics Picks, Predictions and Odds
Fri 25 SepLos Angeles Dodgers vs San Francisco Giants Picks, Predictions and Odds
Fri 25 SepNew York Mets vs Washington Nationals Picks, Predictions and Odds
Fri 25 SepTampa Bay Rays vs Philadelphia Phillies Picks, Predictions and Odds
Sat 26 SepArizona Diamondbacks vs San Diego Padres Picks, Predictions and Odds
Sat 26 SepBaltimore Orioles vs New York Yankees Picks, Predictions and Odds
Sat 26 SepCincinnati Reds vs Toronto Blue Jays Picks, Predictions and Odds
Sat 26 SepColorado Rockies vs Chicago White Sox Picks, Predictions and Odds
Sat 26 SepLos Angeles Angels vs Seattle Mariners Picks, Predictions and Odds
Sat 26 SepNew York Mets vs Washington Nationals Picks, Predictions and Odds
Sat 26 SepPittsburgh Pirates vs Detroit Tigers Picks, Predictions and Odds
Sat 26 SepTampa Bay Rays vs Philadelphia Phillies Picks, Predictions and Odds
Sat 26 SepAtlanta Braves vs Miami Marlins Picks, Predictions and Odds
Sat 26 SepChicago Cubs vs Boston Red Sox Picks, Predictions and Odds
Sat 26 SepCleveland Guardians vs Kansas City Royals Picks, Predictions and Odds
Sat 26 SepHouston Astros vs Athletics Picks, Predictions and Odds
Sat 26 SepLos Angeles Dodgers vs San Francisco Giants Picks, Predictions and Odds
Sat 26 SepSt. Louis Cardinals vs Milwaukee Brewers Picks, Predictions and Odds
Sat 26 SepTexas Rangers vs Minnesota Twins Picks, Predictions and Odds
Sun 27 SepArizona Diamondbacks vs San Diego Padres Picks, Predictions and Odds
Sun 27 SepBaltimore Orioles vs New York Yankees Picks, Predictions and Odds
Sun 27 SepCincinnati Reds vs Toronto Blue Jays Picks, Predictions and Odds
Sun 27 SepColorado Rockies vs Chicago White Sox Picks, Predictions and Odds
Sun 27 SepLos Angeles Angels vs Seattle Mariners Picks, Predictions and Odds
Sun 27 SepLos Angeles Dodgers vs San Francisco Giants Picks, Predictions and Odds
Sun 27 SepTexas Rangers vs Minnesota Twins Picks, Predictions and Odds
Sun 27 SepPittsburgh Pirates vs Detroit Tigers Picks, Predictions and Odds
Sun 27 SepSt. Louis Cardinals vs Milwaukee Brewers Picks, Predictions and Odds
Sun 27 SepAtlanta Braves vs Miami Marlins Picks, Predictions and Odds
Sun 27 SepChicago Cubs vs Boston Red Sox Picks, Predictions and Odds
Sun 27 SepCleveland Guardians vs Kansas City Royals Picks, Predictions and Odds
Sun 27 SepHouston Astros vs Athletics Picks, Predictions and Odds
Sun 27 SepNew York Mets vs Washington Nationals Picks, Predictions and Odds
Sun 27 SepTampa Bay Rays vs Philadelphia Phillies Picks, Predictions and Odds
45 predictions, listed 25 September 2026.

MLB right now

The 2026 regular season is in its last week. ESPN’s standings, read on the evening of 23 September 2026 (7:59 p.m. Eastern, with that night’s games still in progress), had most teams at 157 games played. The last regular-season games on ESPN’s schedule are on Sunday, 27 September, and there are none on Monday the 28th. The postseason starts on Tuesday, 29 September, with Game 1 of the AL and NL Wild Card Series.

DivisionLeaderW-LSecond placeGames behind
AL EastTampa Bay Rays96-61New York Yankees6
AL CentralCleveland Guardians82-75Chicago White Sox1
AL WestHouston Astros and Texas Rangers, tied78-79Seattle Mariners5
NL EastAtlanta Braves92-65Philadelphia Phillies5
NL CentralMilwaukee Brewers98-59Chicago Cubs11
NL WestLos Angeles Dodgers97-60San Diego Padres10

ESPN standings, read 23 September 2026.

Two divisions are still close. Cleveland leads Chicago by one game in the AL Central, and Houston and Texas are level in the AL West with records under .500. The best record in baseball belongs to Milwaukee at 98-59, one game ahead of the Dodgers. At the other end, the Colorado Rockies are 57-100.

Last season

The Los Angeles Dodgers won the 2025 World Series, beating the Toronto Blue Jays four games to three. Game 7 in Toronto on 1 November 2025 went 11 innings, and the Dodgers won it 5-4.

Game 3 in Los Angeles on 27 October went 18 innings before the Dodgers won 6-5. Toronto then won Games 4 and 5 there to lead the series 3-2, and lost the last two at home.

By Tyler Williams | November 28, 2025
By Mario Vega | October 24, 2025
By Mario Vega | August 2, 2025

How MLB betting works here

Baseball betting runs on three markets. The moneyline is a straight bet on who wins. A price with a minus sign is what you risk to win $100, and a plus price is what $100 wins, so the gap between the two sides tells you how big a favorite the sportsbook thinks one team is.

The run line is baseball’s spread, and it is nearly always 1.5 runs. The favorite at -1.5 has to win by two or more; the underdog at +1.5 covers by winning or by losing by exactly one run. It is the way to get a better price on a strong favorite, or a safer one on an underdog you expect to keep it close.

The total is the combined runs scored by both teams, and you bet over or under it. Starting pitchers move baseball prices a great deal, so many sportsbooks let you bet with the listed pitchers: if either announced starter does not start, the bet is voided. Books also sell first-five-innings lines, which settle on the score after five innings and take the bullpens out of the bet.

MLB teams

Every team page, by division:

The baseball predictions hub covers the sport as a whole. If you are thinking of paying for picks, our handicapper site reviews look at the services one by one.

MLB prediction FAQ

Do you publish a prediction for every MLB game? No. Our staff choose selected games each day, and every game date from 11 to 26 September 2026 has at least three, with 16 on the busiest days.

Who writes the MLB predictions? Staff writers. Sal Lombardi and Ethan Cole have written most of them this September, with Mario Vega and others adding more.

When does the 2026 regular season end? Sunday, 27 September 2026, per ESPN’s schedule.

When do the playoffs start? Tuesday, 29 September 2026, with Game 1 of the Wild Card Series in both leagues. ESPN’s schedule, read 23 September, listed the New York Yankees as host of one AL series and every other team as still to be decided.

Who won the 2025 World Series? The Los Angeles Dodgers, 4-3 over the Toronto Blue Jays, with a 5-4 win in 11 innings in Game 7.

What is the run line? Baseball’s spread, set at 1.5 runs in almost every game. The favorite must win by two; the underdog covers by winning or by losing by one.

Find the best angles before kickoff.

Review today’s picks, trends, and betting opportunities.