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The Alabama Crimson Tide host the Clemson Tigers in Tuscaloosa for the ACC/SEC Challenge. Both teams enter on winning streaks, with No. 12 Alabama rebounding from early losses and Clemson riding a four-game surge. Bettors must weigh Alabama’s offensive firepower against Clemson’s balanced scoring and recent momentum. Alabama opened as favorites at home. See full NCAA Basketball odds for market movement. Clemson defeated Alabama A&M 92-56 behind Jestin Porter’s 14 points. Porter, a transfer from Middle Tennessee, has scored in double figures in three straight games and earned MVP honors in the Charleston Classic Palmetto Bracket. Carter Welling leads with 11.6 points per game, while RJ Godfrey adds 11.3 points and a team-best 6.8 rebounds. Clemson averages balanced scoring and

The Iowa State Cyclones host the Alcorn State Braves at Hilton Coliseum in Wednesday NCAA action. No. 10 Iowa State looks to stay perfect while resting star guard Tamin Lipsey ahead of a showdown with Purdue. Alcorn State enters with a 1-8 record, facing one of the toughest non-conference schedules in the nation. Iowa State opened as massive favorites at home. See full NCAA Basketball odds for market movement. Alcorn State fell 83-58 to Louisiana Tech after beating Indiana State 81-74. Shane Lancaster leads with 10.9 points per game and shoots 52.9% from three, while Tycen McDaniels and Davian Williams add scoring depth. The Braves average 67 points per game and shoot 36.8% from three, ranking 74th nationally. Despite their

The Vanderbilt Commodores host the SMU Mustangs at Memorial Gymnasium in Wednesday NCAA action. Both teams enter undefeated at 8-0, making this ACC/SEC Challenge matchup a battle of high-powered offenses. Bettors must weigh Vanderbilt’s home dominance and three-point shooting against SMU’s balanced scoring and resilience in close games. Vanderbilt opened as strong favorites at home. See full NCAA Basketball odds for market movement. SMU edged Mississippi State 87-81 in overtime behind Boopie Miller’s 28 points and Jaron Pierre Jr.’s 24. The Mustangs average 92 points per game, shooting 49.6% from the field and dishing 19 assists per game. Miller has scored double figures in 16 straight games, providing consistency. SMU is 1-0 ATS as underdogs and undefeated overall, showing they

The Texas Longhorns host the Virginia Cavaliers at Moody Center in Wednesday NCAA action. Both teams enter with strong records and fast-paced offenses, making this ACC/SEC Challenge matchup one of the most intriguing of the night. Bettors must weigh Texas’ home dominance against Virginia’s rebounding and three-point shooting efficiency. Texas opened as slight favorites at home. See full NCAA Basketball odds for market movement. Virginia defeated Queens (NC) 94-69 behind Thijs De Ridder’s 21 points. De Ridder leads with 18.0 points per game, while Malik Thomas, Chance Mallory, and Sam Lewis add double-digit scoring. The Cavaliers average 87.6 points per game and rank 11th nationally in rebounds (44.7 per game). Their perimeter shooting (10.4 threes per game) adds offensive balance.