Expert MLB Picks and Previews

The Pirates and Rangers meet Wednesday night at Globe Life Field in Arlington, with first pitch set for 8:05 p.m. ET. Pittsburgh comes in at 13-10, fifth in the NL Central, while Texas is 12-11 and second in the AL West after opening the series with a 5-1 win on Tuesday. This is a pretty interesting early-season matchup because the

The Padres and Rockies are back at Coors Field on Wednesday night, with first pitch set for 8:40 p.m. ET in Denver. San Diego comes in at 16-7 and second in the NL West, while Colorado is 9-15 and fifth after dropping Tuesday’s opener 1-0. The Padres have won three straight, and this is starting to feel like another spot

The White Sox and Diamondbacks meet Wednesday night at Chase Field in Phoenix, with first pitch set for 9:40 p.m. ET on ARID and CHSN. Chicago comes in at 9-14 after blasting Arizona 11-5 on Tuesday, while the Diamondbacks are 13-10 and trying to keep this from turning into a bad home series against a team that came in struggling.

The Dodgers and Giants are back at Oracle Park on Wednesday night, with first pitch set for 9:45 p.m. ET in San Francisco. Los Angeles enters this one at 16-7, tied for first in the NL West, while San Francisco is 10-13 and sitting fourth after taking Tuesday’s opener 3-1. The broadcast is set for SportsNet LA and NBC Sports

The Cardinals and Marlins wrap up their three-game set Wednesday afternoon at loanDepot Park, with first pitch set for 1:10 p.m. ET. St. Louis enters at 14-9, third in the NL Central, and riding strong form with six wins in its last seven games. Miami is 11-13, second in the NL East, but trending the opposite direction at 3-7 over

Mariners call up Will Wilson to face Athletics, not Cole Emerson Seattle Mariners fans hoping for the beginning of the Cole Emerson era will have to wait. With third baseman Brendan Donovan placed on the injured list Monday with a left groin strain, many in Seattle hoped it would be Emerson who got the call when the Mariners opened a

Milwaukee opens this interleague series at Comerica Park on Tuesday night at 12-9, fifth in the NL Central, after Sunday’s 5-3 loss in Miami snapped a four-game winning streak. Detroit is 12-11, second in the AL Central, and although the Tigers dropped Monday’s Patriots’ Day game in Boston 8-6, they return home where they are 8-1 so far. First pitch

Atlanta comes into Tuesday night at 16-7, first in the NL East, and riding a six-game winning streak after Monday’s 9-4 win in Washington. The Nationals are 10-13, third in the division, and just 2-8 at home, so this is already starting to feel like a tough spot for them even before you get to the pitching matchup. First pitch

The Yankees open their first 2026 series against Boston on Tuesday night at Fenway Park, carrying a 13-9 record, first place in the AL East, and a three-game winning streak after sweeping Kansas City. Boston comes in at 9-13, fourth in the division, but the Red Sox did just close their Detroit series with an 8-6 win on Monday. First