Arizona Diamondbacks vs San Diego Padres Picks and Predictions June 13th 2025

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The San Diego Padres will visit the Arizona Diamondbacks at Chase Field on Friday, June 13, 2025. The game will start at 9:40 PM and will be broadcast on APLTV. The weather forecast indicates a very hot day with a light breeze, but the retractable roof at Chase Field should keep conditions stable.

The Padres, managed by Mike Schildt, hold a 38-29 record this season. They are 2 games behind in the NL West. On the other side, the Diamondbacks, led by Torey Lovullo, have a 34-34 record and are 6 games back in the division. Stephen Kolek will start for the Padres with a 3.00 ERA, while Ryne Nelson takes the mound for the Diamondbacks with a 4.60 ERA.

Padres vs Diamondbacks Key Information

  • Sport: Baseball
  • Teams: San Diego Padres vs. Arizona Diamondbacks
  • Venue: Chase Field in Phoenix, AZ
  • Date: Friday, June 13, 2025
  • Betting Odds: Diamondbacks MoneyLine -126, Padres MoneyLine +106

The Padres Can Win If…

The San Diego Padres are coming off a 5-2 loss against the Los Angeles Dodgers. Randy Vásquez pitched 4 2/3 innings, allowing just 2 hits and 1 earned run. Despite the loss, Manny Machado and Xander Bogaerts contributed with key hits.

San Diego’s pitching has been strong this season with a team ERA of 3.47, ranking 6th in the league. Their batting average against is .227, placing them 5th. Stephen Kolek, with an ERA of 3.00, will start and can keep the opposing bats in check.

The Padres’ lineup has some strong hitters like Manny Machado, who is batting .320, and Gavin Sheets with 11 home runs. Fernando Tatis Jr. leads the team with 13 home runs. Their ability to score runs quickly gives them a good chance to win the game.

The Diamondbacks Can Win If…

The Arizona Diamondbacks are coming off a strong performance against the Seattle Mariners, winning 5-2. Eduardo Rodriguez pitched 6 1/3 innings, allowing only 2 earned runs. Eugenio Suárez led the offense with a home run and 4 RBIs, showcasing his power at the plate.

Arizona’s batting lineup is one of their strengths this season. They rank 3rd in the league for on-base percentage and slugging percentage. With 98 home runs, they also hold the 3rd spot in the league, making them a tough team to pitch against.

Ryne Nelson will start for the Diamondbacks, aiming to improve his 4.60 ERA. The team’s pitching staff has delivered 29 quality starts, ranking 7th in the league. With a balanced lineup and solid pitching, the Diamondbacks are well-positioned to secure another win.

The Lean

The Diamondbacks are favored with a MoneyLine of -126, and they have a stronger hitting lineup. They rank 6th in batting average and 3rd in slugging percentage. The Padres, with a MoneyLine of +106, have a weaker pitching staff, ranking 24th in ERA. Based on these factors, the recommendation is to pick the Diamondbacks to win, with a projected score of Diamondbacks 5, Padres 4.

The over/under line is set at 9.5. The Diamondbacks have a solid offense, ranking 3rd in home runs, which suggests they can score runs. The Padres’ pitching struggles with a high ERA of 4.77. Given these conditions, the recommendation is to take the over, with a projected total score of 9 runs.

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NL West Rivals Finally Clash in Key Weekend Series

It has taken nearly half a season, but the San Diego Padres and Arizona Diamondbacks will finally get their first look at each other this weekend. The D-backs enter the crucial three-game series in Arizona on a high note, while the Padres look to bounce back from a tough series loss.

Arizona is Running Hot

The Diamondbacks are playing with swagger. They are coming off a three-game sweep of the Mariners where they launched seven home runs. Their power has been historic; with eight grand slams already this season, they’ve set a new major league record. Eugenio Suarez has led the charge with three homers in his last five games.

“It’s like gears,” said manager Torey Lovullo, describing his team’s connected play. “It’s moving together. It’s a chain reaction.”

San Diego’s Missed Opportunity

The Padres, meanwhile, are coming off a frustrating series loss to the Dodgers where they missed a chance to gain ground in the tight NL West race. San Diego has been playing solid baseball for the last month but knows they need to cash in on their chances.

“They gave us opportunities,” manager Mike Shildt said. “We gave them a few opportunities. They just capitalized a little bit more.” This key divisional series is a chance to get back on track, a topic often explored in our expert betting guide.

A group of San Diego Padres players celebrating a victory on the baseball field, wearing their distinctive tan-striped uniforms.

A Lopsided Pitching Matchup

Friday’s opener features two pitchers heading in completely opposite directions. The Padres will start right-hander Stephen Kolek (3-1, 3.00 ERA), who is on an incredible tear, currently riding a 15 2/3 scoreless inning streak. He’s coming off a stellar performance where he went toe-to-toe with one of his idols, Logan Webb.

The Diamondbacks will counter with Ryne Nelson (2-2, 4.60 ERA), who was shelled for seven runs in just three innings his last time out, struggling badly with his command. This stark contrast on the mound will be a major focus on the scores and odds board.

As these two MLB teams finally face off, the game pits a red-hot pitcher against a red-hot lineup. To see who our experts think has the edge, check out our daily MLB picks.

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Kyle Parker
Kyle Parker | Handicapper

Kyle has put the hammer down for more than 25-years as a bookie, line mover, oddsmaker, and gambler. He knows trends, and has proven it time and again with win, after win.

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