Baltimore Orioles vs Boston Red Sox Picks and Predictions August 25th 2025

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Red Sox Eye Momentum, Orioles Aim for Defensive Clarity

The Boston Red Sox (71–60) come off a dominant 12–1 rout of the Yankees—highlighted by Garrett Crochet’s seven-inning, 11-strikeout gem and a monstrous nine-run ninth inning. Now, they face the Baltimore Orioles (60–70), who enter this four-game series with six wins in their last 11 games.

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Opening Odds

  • Moneyline: Red Sox around –120, Orioles +100
  • Run Line: Red Sox –1.5
  • Total (O/U): 9.5 runs

The Red Sox Can Win If…

  • Newcomer Nathaniel Lowe keeps delivering. Since landing in Boston, he’s batting .438 with seven RBIs and is riding a five-game hitting streak.
  • Brennan Bernardino maintains control. The reliever-turned-starter holds a 2.93 ERA through 46 innings, with a polished 2.57 ERA in career outings against Baltimore.
  • They keep striking early. Boston can lean on a top-five batting average league-wide and MLB’s best doubles rate to generate scoring opportunities and load the bases.

The Orioles Can Win If…

  • Tomoyuki Sugano repeats his recent sharp starts. He’s quietly posted four straight starts without allowing a home run and held Boston to one unearned run in five innings back in April.
  • Offensive depth remains strong, especially as Baltimore has had at least 22 different players homer this year—tying a franchise record.
  • Akin nails the save. Lefty Keegan Akin delivered a crucial five-out save Sunday, showing promise in high-leverage spots.

Key MLB Betting Trends

CategoryBoston Red SoxBaltimore Orioles
Recent MomentumBlasted Yankees 12–1 (7th straight win vs NYY)Won 7 of last 11 games
Offensive SparkLowe is on fire (.438, 7 RBIs)Record-setting power diversity
Starting PitchingBernardino solid; strong vs BALSugano consistently improving
Phone SignalsConfident, peakingSearching for rhythm

The Lean

With momentum, offensive depth, and stellar recent outings, the Red Sox are the safer wager—especially with their bullpen depth and hitting firepower lighting the way.

  • Projected Score: Red Sox 5, Orioles 3
  • Pick: Red Sox Moneyline
  • Total Lean: Under 9.5 Runs

Boston wrapped up their series against the Yankees with a tough 7-2 loss, while Baltimore edged out Houston in a 3-2 win to snap a skid. A deeper dive into the latest MLB game results


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