Baltimore Orioles vs Chicago White Sox Picks and Predictions May 31st 2025

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The White Sox will travel to Oriole Park at Camden Yards to take on the Orioles. This afternoon game is set for Saturday, May 31, 2025, with the first pitch at 4:05 PM. Fans can expect an exciting matchup between these two teams.

On the mound for the White Sox is Davis Martin, who has an ERA of 3.45 and a WHIP of 1.26. The Orioles will counter with Dean Kremer, who has a 5.02 ERA and a WHIP of 1.39. Both pitchers will look to lead their teams to victory in this contest.

White Sox vs Orioles Key Information

  • Sport: Baseball
  • Teams: White Sox vs. Orioles
  • Venue: Oriole Park at Camden Yards
  • Date: Saturday, May 31, 2025
  • Betting Odds: White Sox +1.5 (-128), Orioles -1.5 (+106), White Sox MoneyLine +161, Orioles MoneyLine -193, Over/Under 9.5

The White Sox Can Win If…

The Chicago White Sox are coming off a narrow 2-1 loss against the Baltimore Orioles. Despite the loss, the White Sox showed solid hitting with six hits, including two doubles. Andrew Benintendi contributed with an RBI double, while Lenyn Sosa added two singles, highlighting their potential to drive in runs.

One reason the White Sox can win is their ability to hit doubles, ranking 15th in the league. Their lineup includes Miguel Vargas, who leads the team with eight home runs and 26 RBIs. This power can be crucial in capitalizing against Orioles starter Dean Kremer, who has a 5.02 ERA.

Chicago White Sox player stands at home plate holding a bat, wearing a white pinstripe uniform during a baseball game.

Davis Martin will start for the White Sox, bringing a 3.45 ERA and a WHIP of 1.26. His performance can be pivotal in controlling the Orioles’ offense. With 18 quality starts this season, the White Sox pitching staff has shown they can keep games close, giving their hitters a chance to secure a win.

The Orioles Can Win If…

The Baltimore Orioles secured a narrow 2-1 win against the Chicago White Sox in their most recent game. Zach Eflin pitched a solid seven innings, allowing no runs and striking out six. Ryan Mountcastle and Gunnar Henderson were key contributors, each getting two hits and scoring a run.

The Orioles have shown strong hitting power this season with 60 home runs, placing them 11th in the league. Ryan O’Hearn has been a standout with a .335 batting average and nine home runs. Their ability to hit home runs could be a deciding factor in their upcoming game.

Baltimore Orioles players gather at the pitcher's mound during a game, wearing black jerseys and gray caps under sunny skies.

Dean Kremer will take the mound for the Orioles, bringing a 5.02 ERA and a 1.39 WHIP. While his numbers may not seem dominant, Kremer has the potential to deliver quality innings. With the Orioles’ lineup featuring players like Jackson Holliday and Gunnar Henderson, the team has the offensive tools to support Kremer and secure another win.

The Lean

The Orioles are favored with a moneyline of -193 against the White Sox at +161. Given the Orioles’ better hitting stats, including a higher slugging percentage and more home runs, they are likely to win. The model projects a score of Orioles 6, White Sox 4, supporting a pick for the Orioles to win straight up.

The over/under line is set at 9.5 with the under at -120. Both teams have pitching challenges, but the White Sox have a slightly better ERA. The projected total score is 10, suggesting a slight lean towards the over. However, the under is a safer pick given both teams’ inconsistencies at the plate.

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Orioles Willing to Manufacture Runs Against White Sox

The Baltimore Orioles are proving that you don’t always need power hitting to secure wins — sometimes, a little hustle and smart baserunning does the trick. They’ll aim to keep that gritty energy going on Saturday as they host the Chicago White Sox in the second game of their series.

Baltimore opened the set with a 2-1 victory Friday night, highlighted by a perfectly executed double steal that produced the game-winning run. With two outs in the sixth inning, Ryan O’Hearn intentionally baited a throw at second base, allowing Ryan Mountcastle to break for home — a gutsy gamble that paid off.

“We try to pick our spots and be smart as you can… sometimes you’ve got to take some smart risks,” said Orioles interim manager Tony Mansolino.


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Orioles Finding Ways to Win, White Sox Searching for Stability

Baltimore has now won four of its last six, showing versatility in both the lineup and on the basepaths. Gunnar Henderson collected his 400th career hit in Friday’s game — becoming one of just six Orioles to reach that milestone before turning 24.

“It has been a grind,” Henderson admitted. “I’ve been searching for stuff.”

The team may face a lineup shakeup Saturday depending on the status of Mountcastle, who exited Friday’s game with right hamstring discomfort. His condition will be reevaluated before first pitch.

Dean Kremer (4-5, 5.02 ERA) gets the ball for the Orioles and is coming off a shutout performance over 5 1/3 innings against Boston. While consistency has been a challenge for Kremer this season, he’s been lights-out in two career starts against the White Sox, allowing just one run across 11 2/3 innings.

Chicago counters with Davis Martin (2-5, 3.45 ERA), who has been solid but under-supported — the White Sox are 2-9 in games he’s pitched this season. Saturday will mark his first career appearance against Baltimore. Martin is coming off a quality start against Texas but has struggled with command, walking more batters than he struck out in that outing.

Chicago continues to face adversity, having lost seven of its last eight on the road. On Friday, they placed Miguel Castro on the IL with a knee injury that will require surgery, promoting veteran Dan Altavilla to bolster a depleted bullpen.

“Even as we get older, you just can’t ever give up because there’s always opportunity out there,” Altavilla said. “Injuries happen all the time… it’s just the reality of the game.”

With Baltimore manufacturing runs and Chicago scrambling to find rhythm, Saturday’s matchup sets the stage for compelling angles in MLB Game Predictions and Betting Picks.


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