Baltimore Orioles vs Tampa Bay Rays Picks and Predictions June 28th 2025

Baltimore Orioles vs Tampa Bay Rays June 28th 2025

The Tampa Bay Rays head to Oriole Park at Camden Yards for an afternoon game against the Baltimore Orioles. The Rays, managed by Kevin Cash, have a record of 46-36 this season. They are just one game behind in the AL East standings. The Orioles, with interim manager Tony Mansolino, hold a 35-46 record and are twelve games back in the division.

Both teams have their starting pitchers ready for the game. Zack Littell will take the mound for the Rays, with an ERA of 3.78 and a WHIP of 1.10. On the other side, Zach Eflin starts for the Orioles, holding an ERA of 5.46 and a WHIP of 1.38. The game is set for 4:05 PM, and fans can catch it on FDSSU. The weather forecast predicts a warm day with light rain and a gentle breeze.

Rays vs Orioles Key Information

• Sport: Baseball
• Teams: Tampa Bay Rays vs. Baltimore Orioles
• Venue: Oriole Park at Camden Yards in Baltimore, MD
• Date: Saturday, June 28, 2025
• Betting Odds: Orioles MoneyLine -112, Rays MoneyLine -106

The Rays Can Win If…

The Tampa Bay Rays recently played against the Baltimore Orioles and lost 8-22. Despite the loss, the Rays showed some power with three home runs. Brandon Lowe was a standout, going 3-for-5 with a home run and four RBIs.

The Rays have strong stats that can help them win. They rank 2nd in batting average at .258 and lead the league in stolen bases with 106. Their pitching staff is solid too, with a 3.70 ERA, which ranks 8th in the league.

Key players like Junior Caminero and Brandon Lowe are important for the Rays. Caminero has hit 20 home runs this season, ranking 1st on the team. With Zack Littell starting and his 3.78 ERA, the Rays have a good chance to bounce back.

The Orioles Can Win If…

The Baltimore Orioles had an impressive win against the Tampa Bay Rays, scoring 22-8. Gary Sánchez led the charge with four hits, including a home run. Colton Cowser and Ramón Laureano also contributed with multiple hits and runs.

The Orioles’ offense is strong, ranking 11th in home runs with 96 this season. Their slugging percentage of .399 is ranked 13th, showing their ability to hit for power. With players like Ryan O’Hearn and Jackson Holliday in the lineup, they have the potential to score big.

Zach Eflin will start on the mound for the Orioles. While his ERA is 5.46, he has a winning record of 6-4. With the Orioles’ offense backing him, Eflin has the support needed to secure a win.

The Lean

The Orioles are favored with a moneyline of -112 against the Rays at -106. The Orioles have a better team batting average and on-base percentage compared to the Rays. Given these stats, the recommendation is to take the Orioles to win straight up. The model projects a score of Orioles 6, Rays 5.

The over/under for the game is set at 10.0. The Orioles have a higher earned run average, indicating potential for more runs scored by the Rays. The model projects a total score of 11 runs. Therefore, the recommendation is to take the over on the total.

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The Tampa Bay Rays will look to rebound from a lopsided 22–8 loss to the Baltimore Orioles when they meet again on Saturday afternoon. After expending 209 pitches over eight innings in Friday’s contest, Tampa Bay must find a way to manage its fatigued bullpen while relying on veteran starters in a pivotal midseason matchup. For a deeper look at other upcoming matchups, check out our MLB previews.

Rays Face Bullpen Challenge

Friday’s marathon outing left multiple relievers unavailable or on short rest, and with Cole Sulser and Connor Seabold optioned to Triple-A Durham, manager Kevin Cash has few fresh arms to deploy. The club may need to lean on a “bulk” starter or turn to less-experienced long relievers to bridge late innings. For those weighing their wagering options in light of bullpen uncertainty, our MLB picks offer data-driven insight.

Littell Seeks Rebound

Right-hander Zack Littell (6–7, 3.78) will take the mound for the Rays, aiming to atone for a June 17 start in which he yielded three runs in six innings at Tropicana Field. Littell has struggled with the long ball—22 homers allowed this season—but he did go five frames without surrendering a homer in his most recent outing against Detroit. For context on how this situation fits into larger wagering strategies, see our Expert Betting Guide to MLB.

Orioles Look to Build Momentum

Baltimore’s offense roared back from an early deficit, erupting for 22 runs and handing the Rays a heavy defeat. Interim manager Tony Mansolino will hope that Friday’s performance ignites confidence, though the loss of infielder Jordan Westburg to left-hand discomfort could force a lineup shuffle. If you’re considering locking in your own predictions, you can buy expert picks tailored to matchups like this one.

Key Factors and What to Watch

Saturday’s outcome may hinge on whether Littell can limit Baltimore’s power surge and whether Zach Eflin (6–4, 5.46) can provide length for the Orioles after two recent short outings. Monitoring bullpen usage, lineup adjustments for Westburg’s status, and each starter’s ability to navigate the first three innings will be critical. For standings and handicapping trends, refer to our Best Handicappers Leaderboard to see which analysts have excelled against similar situations this season.