Boston Red Sox vs Los Angeles Angels Picks and Predictions June 4th 2025

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The Los Angeles Angels will take on the Boston Red Sox at Fenway Park. This afternoon game is set for 1:35 PM on Wednesday, June 4, 2025. Fans can catch the action on FDSW.

The Angels, managed by Ron Washington, have a 28-32 record this season. They are 5 games back in the AL West. The Red Sox, led by Alex Cora, hold a 29-34 record and are 10 games back in the AL East. The starting pitchers are José Soriano for the Angels and Lucas Giolito for the Red Sox.

Angels vs Red Sox Key Information

  • Sport: Baseball
  • Teams: Los Angeles Angels vs. Boston Red Sox
  • Venue: Fenway Park in Boston, MA
  • Date: Wednesday, June 4, 2025
  • Betting Odds: Angels MoneyLine +110, Red Sox MoneyLine -130

The Angels Can Win If…

The Los Angeles Angels recently won against the Boston Red Sox, 4-3, in their latest game. Zach Neto played well, going 2-for-5 with 2 runs and 1 RBI. Their starting pitcher, Yusei Kikuchi, managed 5 innings, giving up 3 runs and striking out 5 batters.

With a slugging percentage of .406, the Angels rank 8th in the league, showing their power potential. They are also 3rd in home runs with 87 this season. This ability to hit home runs can be a game-changer in close contests.

 Los Angeles Angels players celebrate after a successful play, wearing red jerseys and helmets during a baseball game.

The Angels’ starting pitcher for the next game, José Soriano, has an ERA of 3.41. His performance can be a key factor in securing another win. The Angels have shown they can win on the road, with recent victories against both the Red Sox and Guardians.


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The Red Sox Can Win If…

The Boston Red Sox recently lost a tight game to the Los Angeles Angels, 4-3. Ceddanne Rafaela was a standout, going 3-for-5 with a home run and two RBIs. Jarren Duran also contributed with two doubles and an RBI, showing the team’s ability to hit extra-base hits.

The Red Sox have a strong offense, ranking 5th in slugging percentage at .414. They are also 2nd in doubles with 115, showing their ability to get runners in scoring position. Rafael Devers leads the team with a .286 batting average and 12 home runs, making him a key player to watch.

Boston Red Sox players celebrate a run at home plate, exchanging a high five while smiling in white uniforms.

Lucas Giolito will start for the Red Sox, and he has the potential to deliver a quality start. He has shown he can keep runs in check, as seen in his previous outing against the Braves. With a solid performance from Giolito and the team’s hitting power, the Red Sox have a good chance to win.

The Lean

The Red Sox are favored with a moneyline of -130, while the Angels are at +110. Based on team stats, the Red Sox have a better batting average and on-base percentage. My model projects the Red Sox to win with a score of 6-4. The recommendation is to pick the Red Sox to win straight up.

The over/under line is set at 10.0 runs. The Red Sox have a lower team ERA than the Angels, suggesting fewer runs allowed. My model predicts a total score of 10 runs. The recommendation is to take the under for this game.

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Angels Eye Sweep as Red Sox Continue One-Run Woes

The Los Angeles Angels will look to seal a series sweep when they face the Boston Red Sox on Wednesday afternoon in the finale of their three-game showdown at Fenway Park. With two close wins already in hand — 7-6 on Monday and 4-3 in 10 innings on Tuesday — the Angels are in position to cap off a perfect road trip against a Red Sox team sinking under the weight of self-inflicted mistakes.

Boston’s latest loss was another in a long line of close defeats. They’ve now dropped 17 one-run games this season, including 13 of their last 15 such contests. Defensive breakdowns have become a costly theme, and their frustration is boiling over.


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Cora Sounds Off After Error-Filled Losses

Monday and Tuesday saw the Red Sox commit a combined five errors — two in the opener and three more in extras on Tuesday. Manager Alex Cora didn’t hold back postgame, taking accountability while openly criticizing the team’s fundamentals.

“We keep making the same mistakes. We’re not getting better. At one point, (it) has to be on me, I guess. Right? I’m the manager.”

Boston leads the majors with 53 errors, and the lack of execution is piling up at critical moments.

“Routine ground balls for double plays we don’t turn. We throw to the wrong bases, we miss cutoff guys… there’s a lot of bad right now,” Cora added.

Angels Playing Clean, Confident Baseball

In contrast, Los Angeles has taken full advantage of Boston’s sloppy play. The Angels turned three double plays on Tuesday, gunned down a runner at the plate, and have shown a defensive sharpness that’s eluded them earlier in the season.

“The good thing is we didn’t make any errors,” manager Ron Washington said. “We kept putting the pressure on them, and they made some mistakes and we took advantage of it.”

Pitching has also stabilized, especially in the bullpen. After early-season struggles, Angels relievers boast a 2.78 ERA over the past 16 games. Reid Detmers, typically a starter, pitched a scoreless 10th on Tuesday to earn his first big league save.

“That’s kind of one thing we take pride in — going out there and getting zeros,” said Detmers. “Yeah, we’ve had some bumps in the road, but you just gotta get over the hump.”

Soriano vs. Giolito in the Finale

On Wednesday, the Angels will give the ball to Jose Soriano (4-5, 3.41 ERA), who’s coming off six scoreless innings in a win over Cleveland. While his only outing against Boston came in relief earlier this year, Soriano has looked more composed in a starting role.

Boston counters with Lucas Giolito (1-1, 4.78 ERA), who delivered a solid 4 2/3-inning effort against Atlanta last time out. Historically, Giolito has a 4-2 mark against the Angels, but with a 5.63 ERA in those outings, he’s been vulnerable.

With both clubs trending in different directions, this is a game that could provide strong value in MLB Game Forecasts and Picks. Look for bullpen depth, defensive efficiency, and recent momentum as deciding factors.


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Mike Williams
Mike Williams | Handicapper

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Mike uses his strong sports knowledge to analyze all the angles to find the most profitable wagers. Iron Mike handicaps MLB, college football, NFL, NBA, and NCAA basketball. I'm an actual sports and gambling junkie!

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