Chicago Cubs vs St. Louis Cardinals July 6th 2025

The St. Louis Cardinals will take on the Chicago Cubs at Wrigley Field on Sunday, July 6, 2025. The game is scheduled to start at 6:10 PM and will be broadcast on ESPN. Fans can expect a warm evening with a light breeze and some light rain, which might affect play.

The Cardinals, led by manager Oliver Marmol, have a 48-42 record this season. They are 5 games back in the NL Central. Erick Fedde will start for the Cardinals, bringing a 4.57 ERA into the game. On the other side, the Cubs, managed by Craig Counsell, hold a 53-36 record. Matthew Boyd will pitch for the Cubs, boasting a 2.65 ERA this season.

Cardinals vs Cubs Key Information

• Sport: Baseball
• Teams: St. Louis Cardinals vs. Chicago Cubs
• Venue: Wrigley Field in Chicago, IL
• Date: Sunday, July 6, 2025
• Betting Odds: Cardinals Moneyline +174, Cubs Moneyline -208

The Cardinals Can Win If…

The St. Louis Cardinals are coming off a win against the Chicago Cubs on July 5th, 2025, with a score of 8-6. Their offense was on point, with 13 hits and 3 home runs. Key players like Nolan Gorman, Alec Burleson, and Yohel Pozo made significant contributions, each hitting a home run.

The Cardinals have some strong stats that could help them win. They rank 4th in doubles with 152 this season. Their batting average of .252 ranks 7th, showing consistency at the plate.

Erick Fedde will start for the Cardinals. Although his record is 3-8, he has shown potential in past games. With support from hitters like Brendan Donovan and Alec Burleson, the Cardinals have a chance to secure another win.

The Cubs Can Win If…

The Chicago Cubs recently played a high-scoring game against the St. Louis Cardinals, losing 8-6. Despite the loss, Michael Busch and Carson Kelly showed strong performances, each hitting home runs. The Cubs managed to get nine hits, including five extra-base hits, demonstrating their offensive potential.

The Cubs have been consistent in their hitting this season, ranking 4th in batting average and 3rd in slugging percentage. They have also hit 135 home runs, placing them 3rd in the league. This power at the plate gives them a strong chance to win any game.

Matthew Boyd will be starting for the Cubs, bringing an impressive 2.65 ERA to the mound. His ability to limit opposing hitters could be key in securing a win. With a solid lineup and Boyd’s pitching, the Cubs are well-positioned to take the game against the Cardinals.

The Lean

The Cubs are favored with a moneyline of -208 against the Cardinals at +174. The Cubs have a stronger hitting lineup, ranking 3rd in slugging percentage and home runs. My model projects the Cubs to win with a score of 5-3. Based on these factors, the recommendation is to pick the Cubs to win straight up.

The total for the game is set at 7.5 runs. The Cubs have a solid offense, and the Cardinals’ pitching ranks 19th in ERA. My model projects a total score of 8 runs. Given the offensive strength and pitching weaknesses, the recommendation is to take the over 7.5 runs.

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Cubs Turn to Steady Matthew Boyd in Rubber Match vs. Cardinals

The Chicago Cubs have been beset by injuries to their starting rotation all season, but veteran left-hander Matthew Boyd has emerged as a crucial stabilizing force. The first-place Chicago Cubs will turn to their steady lefty again on Sunday as they host the rival St. Louis Cardinals in the rubber match of their three-game series.

The Stabilizing Force

With aces like Justin Steele and Shota Imanaga spending significant time on the injured list, Boyd (8-3, 2.65 ERA) has stepped up in a big way. He has won his last two starts, allowing just two total runs over 13 innings.

“Losing the guys we have… we really needed Matt to step up,” said Cubs President of Baseball Operations Jed Hoyer. “And he’s done an amazing job.”

“His steadiness and his just delivering quality innings every time out — it’s stabilizing,” added manager Craig Counsell.

Fedde’s Search for Answers

While Boyd has been excellent, the Cardinals will start a pitcher who is in a deep slump. Right-hander Erick Fedde (3-8, 4.56 ERA) has been shelled in his last two starts, allowing a combined 14 runs in just 8 2/3 innings. He was hit hard by these same Cubs on June 25.

“Obviously, these last two are about as bad as it gets,” a frustrated Fedde said. “I wish I had answers for you. I really do.”

A Lopsided Duel on Paper

The pitching matchup on paper heavily favors the Cubs. Boyd is hot, while Fedde is not. Furthermore, the Cardinals have struggled all season against left-handed pitching, and now they may be without their best right-handed bat, Nolan Arenado, who is day-to-day with a shoulder impingement. This mismatch will be a key focus on the scores and odds board.

The challenges facing the Cardinals’ lineup are a key topic in our expert betting guide. For two MLB teams battling for position in the NL Central, this finale is critical. To see if our experts think the Cubs will take the series, check out our daily MLB picks.