Chicago White Sox vs Cleveland Guardians Picks and Predictions July 13th 2025

Chicago White Sox vs Cleveland Guardians July 13th 2025

The Cleveland Guardians will take on the Chicago White Sox at Rate Field in Chicago, IL. This afternoon game is set for Sunday, July 13, 2025, at 2:10 PM. Fans can catch the action on CLEG as the two AL Central teams meet under scattered clouds and warm conditions.

The Guardians, managed by Stephen Vogt, hold a season record of 45-49. They have a strong division record of 16-9. Joey Cantillo will start for Cleveland, bringing an ERA of 3.79. On the other side, the White Sox, led by Will Venable, have a season record of 32-64. Aaron Civale will start for Chicago, with an ERA of 5.17. Both teams will look to improve their standings in the AL Central.

Guardians vs White Sox Key Information

• Sport: Baseball
• Teams: Cleveland Guardians vs. Chicago White Sox
• Venue: Rate Field in Chicago, IL
• Date: Sunday, July 13, 2025
• Betting Odds: Guardians Moneyline -134, White Sox Moneyline +114

The Guardians Can Win If…

The Cleveland Guardians are coming off a strong 6-2 win against the Chicago White Sox. Tanner Bibee delivered a solid performance, pitching 5 2/3 innings and allowing only 2 earned runs. Key hitters like José Ramírez and Kyle Manzardo made significant contributions, with Manzardo hitting a home run.

The Guardians have a good chance to win with their pitching strength. Joey Cantillo, their starter, has a decent ERA of 3.79, which is better than the White Sox’s starter, Aaron Civale, who has an ERA of 5.17. The Guardians’ pitching staff ranks 11th in batting average against, showing they can limit opponents’ hits.

Offensively, the Guardians have shown power with 97 home runs this season, ranking 17th in the league. José Ramírez leads the team with a batting average of .297 and 18 home runs. With players like Ramírez and Carlos Santana in the lineup, the Guardians have the potential to score runs and secure a win.

The White Sox Can Win If…

The Chicago White Sox are looking to bounce back after a 6-2 loss to the Cleveland Guardians. In that game, Andrew Benintendi led the team with two hits and scored a run. Despite the loss, starting pitcher Sean Burke had a solid outing with five strikeouts over five innings.

The White Sox have shown they can win close games, as seen in their recent 5-4 victory over the Guardians. Lenyn Sosa played a key role with two home runs and two RBIs. Their ability to hit home runs can be a game-changer, especially with players like Miguel Vargas and Andrew Benintendi in the lineup.

On the mound, Aaron Civale will start for the White Sox. While his ERA is 5.17, he has the potential to keep the game close. With support from the bullpen and timely hitting, the White Sox have a chance to secure a win.

Guardians Eye Strong Finish to First Half Against White Sox

Just a week ago, the Cleveland Guardians looked like a team in disarray, mired in a 10-game losing streak and struggling to find answers on either side of the ball. Now, they’re suddenly one of the hottest clubs heading into the All-Star break.

After a commanding 6-2 victory on Saturday against the Chicago White Sox, the Guardians are riding a surge of confidence and production. They’ve now won five of their last six and scored at least four runs in each of those contests — a far cry from their .166 team batting average during the recent skid.

As they prepare to wrap up this four-game set at Guaranteed Rate Field, Cleveland is focused on finishing the first half on a high note. For more betting angles on this matchup, check out the latest MLB picks.

Cantillo Sharp as Guardians Look to Cap Road Trip

Joey Cantillo gets the nod for Cleveland in the series finale. The 25-year-old lefty has impressed since joining the rotation, allowing just three earned runs over his last two starts spanning 7 1/3 innings. In his last outing against Houston, he struck out a season-high seven batters, showing excellent command and confidence on the mound.

Cantillo has handled the White Sox well in the past, owning a 1.00 ERA in two career appearances. He’ll look to contain a Chicago lineup that went hitless after the fourth inning on Saturday and has dropped five of its last seven games.

Guardians manager Stephen Vogt praised reliever Erik Sabrowski, who struck out all four batters he faced in Saturday’s win. The bullpen, bolstered by Cade Smith and Matt Festa, provided 3 1/3 perfect innings to preserve the victory — a testament to Cleveland’s improving depth and execution.

Explore bullpen stats, live lines, and late-game betting edges at our MLB odds and scores page.

Civale Searches for Form in Start Against Former Club

The White Sox will turn to right-hander Aaron Civale, who has struggled since being acquired from the Brewers in mid-June. He’s 0-4 with a 5.40 ERA over his five starts for Chicago and allowed five runs over four innings in his last outing against Toronto.

Civale faces a familiar opponent in the Guardians, the team he pitched for across five seasons. In two career starts against Cleveland, Civale has allowed just two earned runs over 11 innings, including a 1.64 ERA.

Still, control issues have plagued him since arriving in Chicago. Over his last 25 innings, Civale has issued nearly as many walks (13) as strikeouts (14), and opposing batters are making consistent hard contact.

For deeper insight into pitcher-vs-team splits and historical matchups, visit our MLB team analysis section.

Momentum Matters Heading Into the Break

The Guardians’ first half has been a tale of two stretches — a massive slump followed by an equally impressive turnaround. With the potential to win six of seven going into the break, Cleveland could be well-positioned to make a second-half push in the Central.

Catcher Austin Hedges summarized the new energy in the clubhouse: “We could be the hottest team in baseball going into the break. That’s what we expect.”

The White Sox, meanwhile, continue to flounder at the bottom of the standings. Their 32-64 record reflects a year filled with missed opportunities and ongoing struggles on both sides of the game. Saturday’s offensive blackout underscored those issues.

Looking for more pre- and post-break betting insights? Don’t miss our MLB betting guide filled with strategy, team breakdowns, and sharp picks.

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The Lean

The Cleveland Guardians are favored with a moneyline of -134 against the Chicago White Sox, who have a moneyline of +114. The Guardians have a slight edge in pitching with a 3.91 ERA compared to the White Sox’s 4.16 ERA. Given these factors, the recommendation is to pick the Guardians to win straight up, with a projected score of Guardians 5, White Sox 4.

The total for the game is set at 8.5 runs, with the over at -115 and the under at -105. Both teams have struggled offensively, ranking low in batting average and slugging percentage. With the Guardians’ pitching advantage and both teams’ low offensive stats, the recommendation is to take the under, with a projected total score of 9 runs.