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Cleveland Guardians vs Baltimore Orioles July 21st 2025
The Baltimore Orioles will meet the Cleveland Guardians at Progressive Field on Monday, July 21, 2025. The game starts at 6:40 PM and will be broadcast on MASN. Fans can expect a warm evening with clear skies and a light breeze blowing out.
The Orioles, led by interim manager Tony Mansolino, have a 44-54 record this season. They are 13 games behind in the AL East. The Guardians, managed by Stephen Vogt, have a 48-50 record and are 11 games back in the AL Central. Tomoyuki Sugano will start for Baltimore, while Tanner Bibee takes the mound for Cleveland.
Orioles vs Guardians Key Information
- Sport: Baseball
- Teams: Baltimore Orioles vs. Cleveland Guardians
- Venue: Progressive Field in Cleveland, OH
- Date: Monday, July 21, 2025
- Betting Odds: Orioles Moneyline +117, Guardians Moneyline -137
The Orioles Can Win If…
The Baltimore Orioles come off a 5-3 win against the Tampa Bay Rays. In that game, they hit three home runs, showing their power at the plate. Trevor Rogers pitched six innings, allowing just two runs, which helped secure the victory.
The Orioles have a strong lineup with players like Jackson Holliday and Ryan O’Hearn. Holliday leads the team in home runs with 13, while O’Hearn has a .282 batting average. Their ability to hit home runs and get on base makes them a threat to any pitcher.
Tomoyuki Sugano will start for the Orioles with a 4.44 ERA. He has a winning record this season, which gives the team confidence. The Orioles’ offense and Sugano’s pitching could lead them to another win.
The Guardians Can Win If…
The Cleveland Guardians recently took down the None Athletics 8-2. Gavin Williams was the star, pitching seven innings and striking out 11 batters. Angel Martínez shined at the plate, going 3-for-5 with a home run and two RBIs.
The Guardians’ success can be attributed to their strong pitching. Their team ERA stands at 3.96, ranking 18th in the league. They have also given up only 105 home runs, which is the 10th best.
José Ramírez leads the team’s offense with a .295 batting average and 19 home runs. His performance is crucial as the Guardians face the Baltimore Orioles. Tanner Bibee will start on the mound, aiming to improve his 4.29 ERA and secure another win.
The Lean
The Guardians are favored on the moneyline at -137, while the Orioles are at +117. The Guardians have a better pitching staff with an ERA of 3.96 compared to the Orioles’ 4.97. Given the Guardians’ stronger pitching and home advantage, the pick is for the Guardians to win. The projected score is Guardians 5, Orioles 4.
The total for the game is set at 8.5 runs, with the over at -101 and the under at -118. Both teams have had challenges with pitching, as seen by their rankings in ERA and home runs allowed. This suggests a higher scoring game, so the recommendation is to take the over. The projected total is 9 runs.
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Orioles and Guardians Seek Playoff Push in Crucial Four-Game Series
The Cleveland Guardians and Baltimore Orioles open a key four-game set Monday night in Cleveland with both teams looking to climb back into the American League playoff picture. The matchup features a rematch of April’s 6-2 Baltimore win, with Tomoyuki Sugano once again opposing Tanner Bibee.
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Guardians Gaining Momentum Out of the Break
Cleveland enters the series feeling refreshed after taking two of three against the Athletics and scoring eight runs in two of those games—something they’d done just seven times in the first half. The Guardians have now won eight of their last 10 games, building confidence during their best stretch of the season.
“We’ve had a great stretch here,” manager Stephen Vogt said. “We just have to continue to work, continue to work to have good at-bats every single night.”
The Guardians will send Tanner Bibee (5-9, 4.29 ERA) to the mound. Bibee finally snapped a personal five-decision losing skid before the break with a solid outing against the White Sox, but he’s struggled against Baltimore. In April, Bibee gave up three home runs—including one to Gunnar Henderson on just his eighth pitch—en route to a six-run outing over 5 2/3 innings.
Bibee will hope for better run support Monday, as Cleveland’s offense managed just 23 total runs in his nine losses this season.
Need insight into Bibee’s bounce-back potential? Explore the latest MLB Predictions and Picks for key trends.
Orioles Looking for Spark After Skidding
Baltimore arrives in Cleveland after salvaging the final game of their series in Tampa Bay with a rain-delayed 5-3 win, snapping a four-game losing streak. Sitting four games further back in the wild-card race than Cleveland, the Orioles know this series could define their trajectory heading into the deadline.
They’ll turn to Tomoyuki Sugano (7-5, 4.44 ERA), who has battled through the proverbial “rookie wall.” After surrendering 13 runs over 9 2/3 innings in two rough outings, Sugano made adjustments and limited the Mets to three runs over six innings in a much-needed 7-3 win on July 10.
“Tomo’s making adjustments,” manager Tony Mansolino said. “The league has adjusted to him, and he’s got to kind of adjust back. We’re proud of him.”
Sugano dominated Cleveland earlier this season, giving up just two solo homers over seven innings in Baltimore’s April win. The Orioles will need that version of Sugano as they try to make up ground in the standings.
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With both clubs clinging to postseason hopes, this four-game series is pivotal. Can the Guardians continue their surge, or will the Orioles flip the script? Find out where the smart money is with our updated MLB Picks and Analysis.
