Cleveland Guardians vs Houston Astros Picks and Predictions June 7th 2025

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The Houston Astros visit the Cleveland Guardians at Progressive Field on June 7, 2025. The game starts at 4:10 PM, and fans can watch on SCHN. The weather is expected to be mild with clear skies and a light breeze.

The Astros, managed by Joe Espada, have a 35-28 record this season. They are 13-16 on the road. The Guardians, led by Stephen Vogt, hold a 33-29 record. They have performed well at home with a 17-12 record. Starting for the Astros is Hunter Brown, while Gavin Williams takes the mound for the Guardians.

Astros vs Guardians Key Information

  • Sport: Baseball
  • Teams: Houston Astros vs. Cleveland Guardians
  • Venue: Progressive Field in Cleveland, OH
  • Date: Saturday, June 7, 2025
  • Betting Odds: Astros MoneyLine -137, Guardians MoneyLine +115

The Astros Can Win If…

The Houston Astros are coming off a 4-2 win against the Cleveland Guardians. Jeremy Peña led the charge with three hits, while Brendan Rodgers added a home run. Colton Gordon pitched five solid innings, allowing just one run and striking out five.

Houston’s pitching has been strong this season, with a team ERA of 3.56, ranking 9th in the league. Their opponents are hitting just .220 against them, the second-lowest in the league. Astros pitchers have also recorded the most strikeouts with 592, making them a tough team to score against.

Houston Astros pitcher in mid-throw during an MLB game

Jeremy Peña is a key player for the Astros, with a batting average of .318 and nine home runs. Isaac Paredes adds power with 14 home runs, leading the team. With Hunter Brown starting, who has an ERA of 1.83, the Astros have a good chance to secure another win.


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The Guardians Can Win If…

The Cleveland Guardians have shown they can compete with strong performances from key players. In their recent game against the Houston Astros, they had nine hits and one home run. David Fry stood out with a home run and two hits, while Gabriel Arias added two hits, including a double.

Strong hitting stats back up the Guardians’ potential to win. They are ranked 13th in home runs with 63 and have a high number of stolen bases, ranked 9th with 47. These stats highlight their ability to score in multiple ways, which could be crucial in their next game.

Cleveland Guardians pitcher delivering a pitch during an MLB game

Gavin Williams will start for the Guardians, and he has a solid record this season. With a 3.79 ERA and a 5-3 win-loss record, he has shown he can handle pressure on the mound. His performance, along with the team’s ability to get on base and score, makes them a strong contender in their upcoming game.

The Lean

The Astros are favored with a moneyline of -137 against the Guardians at +115. The Astros have a strong pitching staff with a 3.56 ERA, ranked 9th, and a batting average against of .220, ranked 2nd. The Guardians’ pitching ranks lower with a 3.99 ERA, ranked 19th. My model projects the Astros to win 4-3, making the Astros a recommended pick on the moneyline.

The current over/under line is set at 7.0 runs. The Astros’ offense has a batting average of .252, ranked 7th, while the Guardians are at .234, ranked 21st. Given the Astros’ strong pitching and the Guardians’ lower-ranked offense, my model projects a total of 7 runs. This suggests a push, so betting on the under is not recommended.

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Astros’ Hunter Brown Aims for Ninth Win Against Guardians

Hunter Brown will look to cement his status among baseball’s top pitchers Saturday afternoon when the surging Houston Astros seek a second straight win over the Cleveland Guardians at Progressive Field.

Houston opened the series with a 4-2 win Friday and has now won nine of its last 12 games. Another victory would give the Astros back-to-back winning road series for the first time this season.


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Brown Leading the Astros’ Surge

Brown (8-3, 1.83 ERA) has been a force on the mound this season, ranking among MLB leaders in wins, ERA, and opponents’ batting average (.185). He’s riding a stretch of 12 consecutive innings allowing just one run and has delivered 10 quality starts in 12 outings.

“Feels like every time he steps on the mound, he gives us a chance to win ballgames,” Jeremy Pena told the Houston Chronicle.

Last Sunday, Brown overcame four walks to toss six shutout innings in a 1-0 win over Tampa Bay. The right-hander already has five scoreless starts this season.

“Sometimes that’s just the way it goes,” Brown said of working around traffic. “You just navigate it and compete.”

He’ll be hoping for a better outcome than in his lone prior start against Cleveland, when he allowed six runs (two homers) over 5 1/3 innings in April 2024.

Guardians Counter With In-Form Williams

Cleveland will turn to Gavin Williams (5-3, 3.79 ERA), who has been excellent in his last five starts (3-1, 2.30 ERA). In his latest outing, he allowed two unearned runs across 6 2/3 innings in a 4-2 win over the Angels.

“I think that’s the best I’ve ever seen Gavin look,” manager Stephen Vogt said. “He was more efficient… solid for anybody.”

Williams has one previous start vs. Houston, giving up two runs over five innings last season.

The Guardians, though, will need to be sharper on the bases. On Friday, both Jose Ramirez and Angel Martinez were thrown out trying to stretch singles, setting an early tone in the 4-2 loss. Ramirez remains red-hot, batting .389 during a 32-game on-base streak.

Astros Staying Hot at the Plate

Houston’s offense is clicking, led by Pena and Jose Altuve. Pena extended his hitting streak to 12 games Friday, batting .449 during the stretch, while Altuve has hit .364 with 10 RBIs over his last 14 games.

This matchup shapes up as an intriguing spot for those exploring MLB Picks and Betting Predictions, with two red-hot pitchers and playoff-caliber bats on display.


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