Cleveland Guardians vs Tampa Bay Rays Picks and Predictions August 25th 2025

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Boston Looks to Build on Series Win — Orioles Aim to Respond on Home Turf

The Boston Red Sox (71–60) head to Baltimore to take on the Orioles (60–70) to kick off a four-game series Monday night at Camden Yards.

Boston enters following a 3–2 victory to secure three of four against the Yankees — a performance manager Alex Cora praised as the business of winning. Meanwhile, Baltimore, despite a close loss to the Astros Monday, has won seven of their last 11 games, showing signs of consistency.

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Opening Odds

  • Moneyline: Red Sox –117 | Orioles +102
  • Run Line: Red Sox –1.5 (+139)
  • Total (O/U): 9.5 runs (Over –102 | Under –118)

The Red Sox Can Win If…

  • Nathaniel Lowe continues scorching — The first baseman is batting .438 (7-for-16) with 7 RBIs in his past six games and sits on a five-game hit streak .
  • Bernardino holds the fort — Making his first start of the season, lefty Brennan Bernardino has a 2.93 ERA and limits left-handers to a low .201 batting average.
  • Offense remains consistent — Boston ranks 4th in batting average and leads MLB in doubles — offensive depth that can offset Sugano’s veteran presence.

The Orioles Can Win If…

  • Sugano dials in — The veteran starter (10–5, 3.97 ERA) has not allowed a home run in his last four outings and held Boston to one unearned run five innings ago.
  • Baltimore’s deep lineup stays hot — With 22 different players homering this season, the Orioles’ offense remains versatile and explosive.
  • Bullpen performs — Relying on closer Keegan Akin, who delivered a five-out, high-leverage save Sunday, could prove decisive.

Key MLB Betting Trends

CategoryBoston Red SoxBaltimore Orioles
Series MomentumWon 3 of 4 vs Yankees7–4 in last 11 games
Offensive EdgeLowe is red-hot (.438 avg)Most home runs by team men
Starting ArmsBernardino (.201 avg vs LHB)Sugano haven’t surrendered HR in 4 starts
Home/Away SplitsLeading offensivelyDeeper lineup bench

The Lean

Boston’s offense and stout bullpen arm make them the safer play, even on the road. With minor concerns about Bernardino’s workload and Sugano’s steadiness, the matchup nods to Boston in a tight duel:

  • Projected Score: Boston 5, Baltimore 4
  • Pick: Red Sox Moneyline
  • Total Lean: Under 9.5 Runs

The Rays have seen mixed results lately, while Cleveland is looking to rebound from a tough series against Detroit. Reviewing the current MLB game outcomes


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