Detroit Tigers vs Atlanta Braves Picks and Predictions September 21st 2025

Detroit Tigers vs Atlanta Braves September 21st 2025

The Atlanta Braves visit the Detroit Tigers at Comerica Park on Sunday, September 21, 2025, at 1:40 PM. The Braves have a record of 72-83 and are currently on a seven-game winning streak. They are ranked fourth in the NL East Division. The Tigers, with a record of 85-70, lead the AL Central Division but have lost their last five games.

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Spencer Strider will start for the Braves, bringing an ERA of 4.64 and a WHIP of 1.36. On the mound for the Tigers is Casey Mize, who has an ERA of 3.88 and a WHIP of 1.28. The game will be broadcast on FDSSO, and the weather is expected to be mild with overcast clouds and a light breeze.

Braves vs Tigers Key Information

• Sport: Baseball
• Teams: Atlanta Braves vs. Detroit Tigers
• Venue: Comerica Park in Detroit, MI
• Date: Sunday, September 21, 2025
• Betting Odds: Braves Moneyline +101, Tigers Moneyline -120, Braves Runline +1.5 (-195), Tigers Runline -1.5 (+164), Total Over 8.5 (-109), Total Under 8.5 (-112)

The Braves Can Win If…

The Atlanta Braves are on a roll, extending their winning streak to seven games after a thrilling 6-5 victory over Detroit. Rookie Nacho Alvarez Jr. was the hero, blasting two home runs and driving in three runs.

Atlanta’s offense is built around power, ranking 11th in the league with 179 home runs. Matt Olson continues to lead the charge, posting 28 homers and 93 RBIs. Their ability to get on base and strike quickly gives them an edge even when the pitching staff struggles.

On the mound, Spencer Strider will start. Despite a 6-13 record and 4.64 ERA, Strider has regained his form, giving up just three runs over 13 innings in his last two starts. His strikeout ability (8th in the league) can neutralize Detroit’s power bats.

Early Team Snapshot

The Tigers Can Win If…

The Detroit Tigers nearly stole Saturday’s game but let a late lead slip away in a crushing 6-5 loss. Spencer Torkelson powered the lineup with a home run and three RBIs, while Jahmai Jones added three hits.

Casey Mize gets the call on the mound. At 14-5 with a 3.88 ERA, he’s been one of Detroit’s most consistent arms this season. His ability to pitch deep into games could give the Tigers’ bullpen some relief after a tough stretch.

Offensively, the Tigers have shown they can hit for power, ranking 8th with 193 home runs. Alongside Torkelson, Gleyber Torres and Zach McKinstry provide solid contact hitting, giving Detroit multiple ways to score runs.

The Lean

The Tigers enter as slight moneyline favorites at -120, while the Braves are priced at even money (+100). Detroit’s stronger pitching, led by Mize, makes them the pick to win 5-4.

The total is set at 8.5 runs. With both clubs producing consistent offense, the over is the lean. The projection of nine combined runs aligns with recent trends, making the over 8.5 (-110) a smart play.

Betting Trends

• Braves are 5-0 in their last five games overall.
• Tigers are 1-8 in their last nine contests.
• Over has cashed in 6 of Detroit’s last 8 home games.

For more plays and daily analysis, check the MLB picks section.

Matchup Analysis

This matchup comes at a critical time for Detroit. Once thought to be running away with the AL Central, the Tigers are now fighting to hold off the Guardians. Their bullpen has been shaky, putting pressure on starters like Mize to carry the load.

Atlanta, already out of playoff contention, is playing spoiler while showcasing young talent. Alvarez Jr.’s breakout performance is a positive sign for the future, and the Braves’ ability to score late has made them dangerous even in lost seasons.

Stay updated with live odds and line movement on the MLB odds page.

Late Season Factors

Both teams enter with different motivations. The Braves are evaluating young players while the Tigers are in desperation mode, clinging to a shrinking division lead. The psychological edge may lie with Atlanta, who are playing freely without pressure.

For strategy insights on how to approach late-season games, consult the expert MLB betting guide. It breaks down bankroll management and value betting when playoff implications create volatility.

Final Projection Table