Houston Astros vs Chicago White Sox Picks and Predictions June 10th 2025

Houston Astros vs Chicago White Sox June 10th 2025

The Chicago White Sox will take on the Houston Astros at Daikin Park on Tuesday, June 10, 2025. The game is scheduled to begin at 8:10 PM, and fans can watch it on SCHN. This night game will be played under a retractable roof, which might be necessary given the forecast of light rain and very hot conditions.

The White Sox, managed by Will Venable, have struggled this season with a record of 22-44. They face a tough challenge against the Astros, who have a solid 36-29 record under the guidance of manager Joe Espada. Shane Smith will start on the mound for the White Sox, while Lance McCullers Jr. will pitch for the Astros.

White Sox vs Astros Key Information

• Sport: Baseball
• Teams: Chicago White Sox vs. Houston Astros
• Venue: Daikin Park in Houston, TX
• Date: Tuesday, June 10, 2025
• Betting Odds: Astros MoneyLine -196, White Sox MoneyLine +163

The White Sox Can Win If…

The Chicago White Sox recently played against the Kansas City Royals, losing 5-7. Despite the loss, Miguel Vargas stood out with a home run and three RBIs. The White Sox have shown they can score runs, as seen in their previous games against the Royals where they won 4-1 and 7-2.

Key stats show the White Sox have potential to win. They rank 13th in doubles with 94 and have a solid 9th rank in stolen bases with 47. Their starting pitcher, Shane Smith, has an ERA of 2.46, providing a strong presence on the mound.

In their next game, the White Sox will rely on players like Mike Tauchman, who has a batting average of .321. Chase Meidroth, hitting .312, also adds strength to the lineup. With a combination of solid pitching and key hitters, the White Sox have a good chance to win.

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The Astros Can Win If…

The Houston Astros are coming off a close 4-2 loss against the Cleveland Guardians. Jake Meyers had a standout performance, going 4-for-4 at the plate. Despite the loss, the Astros showed solid pitching with Brandon Walter throwing six innings and striking out five batters.

Offensively, the Astros have been strong this season with a team batting average of .252, ranking 7th in the league. They have hit 63 home runs, showing their power potential. Jeremy Peña is leading the team with a .318 batting average and has been a key player in driving in runs.

The Astros’ pitching staff has been effective, with an earned run average of 3.56, placing them 9th in the league. Their opponents are hitting just .220 against them, the 2nd best mark in the league. Lance McCullers Jr. will start the next game, and his experience could be vital for the Astros to secure a win against the Chicago White Sox.

The Lean

The Astros are favored with a MoneyLine of -196. With a strong batting average of .252 and a pitching ERA of 3.56, they have the edge over the White Sox. The White Sox have a MoneyLine of +163 and struggle with a .223 batting average. My model projects the Astros to win with a score of 5-3.

The total for the game is set at 8.0. The Astros’ solid pitching and the White Sox’s lower batting average suggest a lower-scoring game. My model projects a total score of 8, so taking the under 8.0 is recommended.

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Astros Ride Road Momentum Into Home Series Against White Sox

The Houston Astros return to Minute Maid Park riding a wave of momentum after securing their first winning road trip of the season. Now sitting atop the American League West, the Astros aim to keep rolling as they host the Chicago White Sox for a three-game series beginning Tuesday.

Houston posted a 4-2 mark on its six-game road swing through Pittsburgh and Cleveland — a notable turnaround after struggling in away games earlier this year. Despite falling in the series finale to the Guardians, the Astros have won 11 of their past 16 games.

“Another series win on the road,” Astros manager Joe Espada said.

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McCullers Anchors Astros’ Rotation

Right-hander Lance McCullers Jr. (1-1, 4.44 ERA) will take the mound Tuesday night, aiming to continue his strong return to form. After a rocky second start in May — his first after more than two seasons sidelined by injury — McCullers has been stellar, posting a 2.21 ERA with 29 strikeouts across his past four starts. The Astros won all four of those outings.

His last appearance was a vintage performance: six shutout innings with seven strikeouts against the Pirates for his first regular-season win since September 2022.

McCullers also boasts an impressive track record against the White Sox, going 4-1 with a 1.98 ERA in seven career starts. He faced Chicago earlier this season, tossing 3 2/3 scoreless innings in a no-decision.

White Sox Rookie Impressing in Rotation

The White Sox will counter with rookie right-hander Shane Smith (2-3, 2.45 ERA), who has been one of the bright spots in an otherwise challenging season for Chicago. Smith leads the team with a 1.7 bWAR and sports the ninth-lowest ERA by a White Sox pitcher through 12 career starts.

Smith snapped a six-start winless streak in his last outing, firing 5 1/3 scoreless innings against the Tigers. Though he’ll be making his first career start versus Houston, Smith already proved capable against AL West foes, striking out six over five innings against Seattle last month.

Chicago Showing Grit Despite Setbacks

Chicago had its three-game winning streak snapped Sunday in a 7-5 loss to the Royals — its 25th defeat this season by one or two runs. Yet, the White Sox battled back from a five-run deficit in the ninth to nearly steal the game.

“Another example of them continuing to fight,” White Sox manager Will Venable said.

As Houston returns home, fans and bettors alike should expect a competitive series. For added insight and sharper wagers, exploring the latest MLB betting picks and predictions can help break down this intriguing matchup.

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