Los Angeles Dodgers vs San Diego Padres Picks and Predictions August 16th 2025

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San Diego Padres vs Los Angeles Dodgers Picks and Predictions (August 16, 2025)

Snell Faces Former Club, Dodgers Look to Gain Ground in NL West

The San Diego Padres and Los Angeles Dodgers meet Saturday night in a high-stakes NL West showdown at Dodger Stadium.

The Padres (69-52) lead the division by just one game over the Dodgers (68-53). Both clubs enter this matchup in very different forms — San Diego has gone 8-2 in its last 10 games, while Los Angeles snapped a four-game losing streak with a narrow 3-2 win in Friday’s series opener.

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This game features a marquee pitching matchup: Dylan Cease (5-10, 4.52 ERA) for San Diego vs. Blake Snell (2-1, 2.37 ERA) for Los Angeles, who will face his former Padres teammates for the first time since leaving in free agency.

Match Information

  • Sport: Baseball (MLB)
  • Teams: San Diego Padres vs Los Angeles Dodgers
  • Venue: Dodger Stadium, Los Angeles, CA
  • Date: Saturday, August 16, 2025
  • Start Time: 9:10 PM ET
  • Broadcast: National TV

Betting Odds

MarketOdds
Padres Moneyline+110
Dodgers Moneyline-130
Padres Runline +1.5-196
Dodgers Runline -1.5+163
Total Over 8.0-107
Total Under 8.0-114

The Padres Can Win If…

San Diego’s balanced offense continues producing. The Padres are 6th in batting average (.252) and 7th in OBP, with consistent contributions from Fernando Tatis Jr., Jake Cronenworth, and recent trade pickup Ramón Laureano, who already has three home runs with the club.

The Padres’ biggest strength is their elite pitching staff (3.57 ERA, 2nd MLB), which has held opponents to a league-best .226 batting average. If Dylan Cease can find the form he showed in June against LA — seven scoreless innings with 12 strikeouts — the Friars can extend their NL West lead.

The Dodgers Can Win If…

Blake Snell keeps his dominance rolling. Since returning from injury, the lefty has looked sharp with 18 strikeouts in his last two starts, including 10 in five shutout innings vs. Toronto.

The Dodgers’ offense is still one of the best in baseball, ranking 4th in batting average (.255), 2nd in slugging (.441), and 2nd in home runs (180). With Shohei Ohtani (43 HRs) and Mookie Betts setting the tone, LA has the power to overwhelm even a strong Padres rotation.

Key Stats Comparison

CategoryPadresDodgers
Record69-52 (1st NL West)68-53 (2nd NL West)
Last 10 Games8-24-6
Team Batting Avg.252 (6th MLB).255 (4th MLB)
Home Runs162 (8th MLB)180 (2nd MLB)
Team ERA3.57 (2nd MLB)4.17 (15th MLB)

The Lean

This game is razor-close, but Snell’s hot form and LA’s offensive firepower give the Dodgers the edge at home.

Model Projection: Dodgers 5, Padres 4

  • Pick: Dodgers (-130)
  • Total Lean: Over 8.0 (-107)

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