Los Angeles Dodgers vs San Francisco Giants Picks and Predictions September 19th 2025

Los Angeles Dodgers vs San Francisco Giants September 19th 2025

The San Francisco Giants will take on the Los Angeles Dodgers at Dodger Stadium on Friday, September 19, 2025. The Giants hold a record of 76-76 and are ranked fourth in the NL West. They recently won their last game and have a 4-6 record in their last ten games.

The Dodgers, with a record of 85-67, are leading the NL West. They also come into this game with a recent win and a strong 7-3 record in their last ten games. The game will start at 10:10 PM and will be broadcasted on APLTV. Weather conditions are expected to be clear with a light breeze.

Giants vs Dodgers Key Information

• Sport: Baseball
• Teams: San Francisco Giants vs. Los Angeles Dodgers
• Venue: Dodger Stadium in Los Angeles, CA
• Date: Friday, September 19, 2025
• Betting Odds: Giants Moneyline +142, Dodgers Moneyline -169

The Giants Can Win If…

The San Francisco Giants are coming off a strong win against the Arizona Diamondbacks, 5-1. Justin Verlander was key, pitching seven innings and allowing just three hits with no runs. Christian Koss also contributed with two RBIs, helping the Giants secure the victory.

The Giants have shown they can hit home runs, ranking 14th in the league with 162 homers this season. Their pitching has been solid too, with an ERA of 3.86, placing them 11th overall. They have given up the fewest home runs in the league, which could be a big factor in their next game.

Rafael Devers is a player to watch, with 31 home runs and 103 RBIs this season. His performance at the plate can drive the Giants’ offense. With Robbie Ray starting on the mound, boasting an ERA of 3.50, the Giants have a reliable pitcher to lead them in their next game.

The Dodgers Can Win If…

The Los Angeles Dodgers come into this game after a solid 5-0 win against the Philadelphia Phillies. Blake Snell was dominant on the mound, pitching seven innings with 12 strikeouts and no runs allowed. Key hitters like Freddie Freeman and Shohei Ohtani contributed with home runs, showcasing their ability to score efficiently.

The Dodgers have impressive stats this season that can lead them to victory. They rank second in slugging percentage at .440 and have hit 225 home runs, also placing them second in the league. Their pitching staff is strong too, with a batting average against of .234, ranking fifth, which can limit the Giants’ scoring opportunities.

Clayton Kershaw will start for the Dodgers, bringing his experience and skill to the game. With a 10-2 record and a 3.53 ERA, Kershaw can control the game from the mound. His performance, combined with the Dodgers’ powerful lineup, gives them a strong chance to win against the Giants.

The Lean

The Dodgers are favored to win with a moneyline of -169. The Giants have a moneyline of +142. The Dodgers have strong hitting stats, ranking 5th in batting average and 2nd in slugging percentage. My model projects the Dodgers to win with a score of 5-3. The Dodgers’ offensive power gives them the edge in this game.

The total for the game is set at 8.5 runs. The Dodgers’ strong offense and the Giants’ pitching rank of 11th in ERA suggest a higher scoring game. My model projects a total of 8 runs. I recommend taking the under 8.5 at -115, as the combined score is likely to stay below the set total.

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Kershaw’s Farewell on the Home Mound

Clayton Kershaw will take the mound at Dodger Stadium for the final regular-season home start of his career when the Los Angeles Dodgers host the San Francisco Giants on Friday night. The left-hander, who announced Thursday that this will be his last season, gets a fitting sendoff against a rival he has dominated throughout his 18-year career.

Kershaw has faced the Giants more than any other team, compiling 62 appearances and 60 starts against them. His 27-16 record with a 2.08 ERA over 407 1/3 innings highlights his effectiveness in the rivalry. Dodgers fans will have one more chance to see him add to that history in what promises to be an emotional evening.

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Dodgers Fighting for the Division

Los Angeles enters the matchup with an 86-67 record and a three-game lead over the San Diego Padres in the NL West. The Dodgers earned a 2-1 victory Thursday behind a combined one-hitter from six pitchers, keeping the division lead intact.

Kershaw has been a critical part of that success, going 10-2 with a 3.53 ERA in 20 starts this season. In two outings against the Giants this year, he is 1-1 with a 3.60 ERA. His impact on the Dodgers’ playoff push cannot be overstated, with manager Dave Roberts crediting Kershaw’s role in keeping the club atop the standings.

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Emotional Impact of Kershaw’s Decision

While Kershaw admits he will miss the competition, he emphasized that the camaraderie and celebrations after victories are what he will truly cherish. Teammates, including Freddie Freeman, noted that emotions around his retirement announcement are only beginning to surface.

Dodger Stadium has been the backdrop for many of his greatest moments, including 117 of his 222 career wins and his 3,000th career strikeout earlier this season against the Chicago White Sox.

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Giants Still in the Hunt

The Giants enter the contest at 76-77, sitting three games out of the final NL wild-card spot with just over a week remaining. On Thursday, they managed only one hit—a Patrick Bailey single in the second inning—despite drawing 10 walks. They struck out 14 times and dropped a game when allowing two runs or fewer for the first time since Aug. 16.

Left-hander Robbie Ray (11-7, 3.50 ERA) will start for San Francisco. In his last outing, Ray was tagged for five runs over four innings in a loss to the Dodgers. He has 24 career starts against Los Angeles, posting a 9-7 record with a 3.54 ERA, but will need better mechanics this time to give the Giants a chance.

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Latest Betting Trends

• The Dodgers are 5-2 in their last seven home games.
• Los Angeles has won seven of Kershaw’s last nine starts against the Giants.
• San Francisco is 2-6 in its last eight road games.
• The under has hit in four of the last six meetings between these clubs.
• Robbie Ray’s teams are 3-7 in his last 10 starts against the Dodgers.

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Looking Ahead

The matchup is more than just another chapter in the Dodgers-Giants rivalry. It’s a celebration of one of the greatest pitchers of his generation and a chance for Los Angeles to strengthen its hold on the division. For San Francisco, it’s a must-win scenario to keep fading playoff hopes alive.

For fans and bettors tracking outcomes throughout the season, check the latest MLB game results