Miami Marlins vs Chicago Cubs Picks and Predictions May 20th 2025

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Marlins vs Cubs

The Miami Marlins visit Wrigley Field to take on the Chicago Cubs on Tuesday, May 20 at 1:20 PM CT. Expect breezy conditions with periods of rain and thunderstorms, a high near 68°F and a low around 55°F.

Marlins’ Comeback Culture

Miami has thrived in late-game drama, recording its sixth walk-off victory Monday when Jesus Sanchez clubbed a homer and delivered a two-run triple. Having won four of five, the Marlins carry resilience and momentum into Game 2 of this three-game set.

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Cubs’ Bullpen Shakeup

Chicago saw its three-game win streak snapped in Monday’s 8-7 loss, and reliever Porter Hodge now lands on the IL with an oblique issue. Manager Craig Counsell may lean on Daniel Palencia, Ryan Pressly, or Drew Pomeranz in high leverage, reshaping late-inning matchups.

Pitching Matchup

The Cubs will send Jameson Taillon (2-3, 4.53 ERA) to the mound for his second straight start against Miami; he’s 3-1 with a 1.63 ERA in five career outings versus the Fish. Countering is lefty Ryan Weathers (1-0, 1.80 ERA) making his season debut after a flexor strain, and he impressed with five solid innings last week.

X-Factors and Strategy

Taillon’s tendency to yield homers—eight in his last 16 innings—could spell trouble in a hitter-friendly park. Watch for Seiya Suzuki’s power against Weathers, who owns a 6.75 ERA in career games versus Chicago. Miami’s depth in clutch spots will also test a reshuffled Cubs bullpen.

Our MLB Betting Picks

Backing the Marlins on the money line offers value, given their late-game prowess and Taillon’s home run vulnerability. Consider the over on total runs, as both the Marlins and Cubs have combined for 15 runs through two meetings this season.

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Miami Marlins
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Chicago Cubs
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Jim Feist
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Jimmy Adams
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Neal Harris
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Frankie the Fan
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Mike Williams
Mike Williams | Handicapper

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Mike uses his strong sports knowledge to analyze all the angles to find the most profitable wagers. Iron Mike handicaps MLB, college football, NFL, NBA, and NCAA basketball. I'm an actual sports and gambling junkie!

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