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Miami Marlins vs San Diego Padres July 22nd 2025
The San Diego Padres will play against the Miami Marlins at loanDepot Park in Miami, FL. This night game is set for Tuesday, July 22, 2025, at 6:40 PM. The weather forecast mentions light rain, but with the retractable roof, it may not affect the game.
The Padres hold a 55-45 record and are 3 games behind in the NL West. They have a road record of 24-27. The Marlins stand at 46-53, trailing 10 games in the NL East, with a home record of 22-29. Stephen Kolek will start for the Padres, while Edward Cabrera takes the mound for the Marlins.
Padres vs Marlins Key Information
- Sport: Baseball
- Teams: San Diego Padres vs. Miami Marlins
- Venue: loanDepot Park in Miami, FL
- Date: Tuesday, July 22, 2025
- Betting Odds: Padres Moneyline -104, Marlins Moneyline -116, Padres Runline -1.5 (+160), Marlins Runline +1.5 (-197), Total Over 8.0 (-114), Total Under 8.0 (-107)
The Padres Can Win If…
The San Diego Padres recently won a tight game against the Miami Marlins, 2-1. Randy Vásquez pitched 4 1/3 innings, allowing just one run. Jackson Merrill and Xander Bogaerts contributed with key hits, helping the Padres secure the win.
The Padres have strong pitching this season, with a team ERA of 3.60, ranked 3rd in the league. Their batting average against is also impressive at .229, placing them 3rd. These stats show that the Padres have the ability to limit opponents’ scoring opportunities.
Manny Machado is a key player for the Padres, with a .285 batting average and 18 home runs. His performance is essential for the team’s offensive success. With players like Machado and strong pitching, the Padres have a good chance to win the upcoming game.
Team Comparison
| Statistic | San Diego Padres | Miami Marlins |
| Bullpen ERA | 3.15 (1st in MLB) | Not Mentioned |
| Saves | 35 (1st in MLB) | Not Mentioned |
| Series Status | Lead series 1-0 | Trail series 0-1 |
| Recent Team Form | Took 2 of 3 from Washington | 21 wins in last 33 games |
The Marlins Can Win If…
The Miami Marlins are looking to bounce back after a close 2-1 loss to the San Diego Padres. Eury Pérez pitched five innings, allowing two runs with five strikeouts. Kyle Stowers hit a home run, and Xavier Edwards went 3-for-4, showing their potential to spark the offense.
The Marlins have a team batting average of .253, ranking 7th in the league. Their ability to hit doubles, with 165 on the season, ranks them 9th. These stats show their capability to generate runs and put pressure on opposing pitchers.
Edward Cabrera will start for the Marlins with a 3.61 ERA and a WHIP of 1.26. His solid performance on the mound can keep the Padres’ hitters in check. With key players like Kyle Stowers and Xavier Edwards in the lineup, the Marlins have the tools to secure a win.
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Daily MLB Lineup Tips
The Lean
The Padres are a good pick for the moneyline at -104. Their pitching ranks 3rd in ERA and batting average against, which gives them an edge. The model projects the Padres to win with a score of 5-3.
For the over/under, the total is set at 8.0. The model projects a combined score of 8, aligning with the line. Considering both teams’ hitting stats and pitching strengths, the under at 8.0 (-107) is recommended.
Starting Pitcher Matchup: Tuesday
| Pitcher | Team | 2025 Record | 2025 ERA | Career vs. Opponent | Notes |
| Dylan Cease | San Diego Padres | 3−9 | 4.64 | 0−1, 2.45 ERA (2 starts) | Has lost his last 3 decisions. |
| Sandy Alcantara | Miami Marlins | 4−9 | 7.14 | 2−2, 4.04 ERA (5 starts) | 2022 Cy Young winner; returning from surgery. Has an 8.61 ERA in his last 4 starts. |
Struggling Aces Alcantara and Cease Seek Redemption as Marlins Host Padres
A marquee pitching matchup with a twist is set for Tuesday night in Miami, as two hurlers with impressive resumes but troubled seasons take the mound. The Miami Marlins will send 2022 National League Cy Young Award winner Sandy Alcantara to face the San Diego Padres and right-hander Dylan Cease, as both pitchers look to reverse their recent fortunes.
The matchup presents a study in contrast. While the starters have struggled, the San Diego bullpen has been a fortress. Leading the majors with a 3.15 ERA and 35 saves, the Padres’ relief corps demonstrated its dominance in Monday’s 2-1 series-opening victory, tossing 432 scoreless innings. The bullpen features a historic trio of All-Stars—Robert Suarez, Adrian Morejon, and Jason Adam—all of whom contributed to Monday’s win.
“Those are high-end bullpen arms,” noted Marlins manager Clayton McCullough.
For the starters, the path has been rockier. Cease, who is nearing the one-year anniversary of his no-hitter, has posted a disappointing 3−9 record with a 4.64 ERA and has lost his last three decisions. Alcantara’s struggles are even more pronounced. In his return from Tommy John surgery, he holds a 4−9 record with a 7.14 ERA, including a staggering 8.61 ERA over his last four outings.
The game may hinge on which offense can provide its pitcher with much-needed support. The Padres’ bats were quiet on Monday, managing only five hits and going 1-for-7 with runners in scoring position. Key contributors Jake Cronenworth and Jose Iglesias will be looking to bounce back after a combined 0-for-7 night.
The Marlins, however, have found a spark in Kyle Stowers. The team’s home run leader is on a torrid streak, blasting his 22nd homer on Monday, which marked his sixth in the last five games. They also have high hopes for rookie catcher Agustin Ramirez, whose bat has produced 14 homers and 44 RBIs this season, even as his defense remains a work in progress.
To win their third consecutive series, the Marlins must win both remaining games against a Padres team that has perfected the art of closing games out.
