Milwaukee Brewers vs Baltimore Orioles Picks and Predictions May 20th 2025

Orioles vs Brewers

The Baltimore Orioles travel to American Family Field to face the Milwaukee Brewers on Tuesday, May 20 at 7:10 PM CT. Expect windy, rainy conditions with a high near 47°F and a low around 44°F throughout the evening.

Orioles’ Struggles Under New Leadership

Interim manager Tony Mansolino is still seeking his first win, with Baltimore dropping three straight since taking over. Despite hard contact—highlighted by Cedric Mullins’s three-run homer Monday—the Orioles fell 5-4 in the series opener and now look to shake off a seven-game slide.

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Bullpen Opener Strategy

Baltimore will employ lefty Keegan Akin (0-0, 3.27 ERA) as an opener, followed by Chayce McDermott on the mound. Akin shined in relief this year, allowing eight earned runs over 22 innings, and owns a 0.00 ERA in three appearances against Milwaukee.

Henderson’s Early Success

Milwaukee counters with right-hander Logan Henderson (2-0, 2.45 ERA), who has limited opponents to a .184 average across his first 11 innings. After allowing just one run in six innings during his debut, he’ll aim to continue his strong start against a lineup desperate for a breakout.

X-Factors and Adjustments

Ramon Laureano’s .395 average over his last 11 games provides a spark atop Baltimore’s order, while William Contreras’s hot bat—from four hits Monday—will test the opener strategy. Weather and wind could impact how both staffs manage their arsenals.

Our MLB Expert Picks

Backing the Brewers on the money line offers value given Henderson’s command and the opener approach’s uncertainty. For alternate action, consider the under on runs as wind and rain often suppress offense at American Family Field.