Milwaukee Brewers vs Pittsburgh Pirates Picks and Predictions June 25th 2025

Milwaukee Brewers vs Pittsburgh Pirates June 25th 2025

The Pittsburgh Pirates head to American Family Field to take on the Milwaukee Brewers on Wednesday, June 25, 2025. This afternoon game is set to start at 2:10 PM and will be broadcast on MLBN. The weather forecast calls for a mild day with light rain, but the retractable roof at the stadium might keep the conditions in check.

The Pirates, managed by Don Kelly, hold a record of 32-49 this season. They are 15 games back in the NL Central. Their road record stands at 12-28. The Brewers, managed by Pat Murphy, have a record of 44-36 and are 2 games back in the division. At home, they hold a 24-16 record. Starting pitchers for the game are Paul Skenes for the Pirates and Jacob Misiorowski for the Brewers.

Pirates vs Brewers Key Information

• Sport: Baseball
• Teams: Pittsburgh Pirates vs. Milwaukee Brewers
• Venue: American Family Field in Milwaukee, WI
• Date: Wednesday, June 25, 2025
• Betting Odds: Pirates MoneyLine -117, Brewers MoneyLine -101

The Pirates Can Win If…

The Pittsburgh Pirates recently played against the Milwaukee Brewers, where they lost 3-9. Andrew Heaney had a tough time on the mound, giving up seven earned runs in four innings. Despite the loss, Nick Gonzales hit a home run and drove in three runs, showing his potential at the plate.

The Pirates have a strong chance to win with their aggressive base running, ranking 5th in stolen bases with 71. Their pitching staff has also been solid, with a team ERA of 3.86, placing them 13th in the league. Paul Skenes, their starting pitcher for the next game, boasts an impressive ERA of 1.85, which can help keep the Brewers’ bats in check.

Key players like Andrew McCutchen and Nick Gonzales are crucial for the Pirates. McCutchen leads the team with a batting average of .259 and eight home runs. Gonzales, batting .316, has been a consistent performer and can provide the offensive spark they need to secure a win.

The Brewers Can Win If…

The Milwaukee Brewers had a strong performance in their recent game against the Pittsburgh Pirates, winning 9-3. Joey Ortiz led the charge with two home runs and four RBIs. Caleb Durbin also contributed with a home run and three RBIs, showing the depth in their lineup.

The Brewers’ lineup has been effective, with a team batting average of .247, ranking 11th in the league. Their ability to draw walks is notable, ranking 9th with 275 walks this season. This patience at the plate can help them create scoring opportunities and put pressure on opposing pitchers.

Starting pitcher Jacob Misiorowski is another reason the Brewers can win. His ERA of 1.64 and WHIP of 0.55 demonstrate his ability to limit opposing offenses. With Misiorowski on the mound, the Brewers have a solid chance to control the game from the start.

The Lean

The Pirates are favored with a moneyline of -117 against the Brewers at -101. The Pirates have a slight edge in pitching with a lower batting average against. My model projects the Pirates to win with a score of 4-3. Considering these factors, the recommendation is to pick the Pirates to win straight up.

The over/under line is set at 6.5 for this game. Both teams have similar ERA rankings, but the Brewers have a higher slugging percentage. My model projects a total score of 7 runs. Based on this, the recommendation is to take the over for this game.

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An “Epic” Duel: Paul Skenes and Jacob Misiorowski Face Off in Milwaukee

It is not just another game in June. It is a must-see event, a matchup that has been billed as “epic” and has the baseball world buzzing. Two of the game’s brightest young stars and hardest throwers will go head-to-head on Wednesday afternoon as Paul Skenes and the Pittsburgh Pirates face Jacob Misiorowski and the host Milwaukee Brewers in a decisive rubber match.

A Battle of Flamethrowers

The hype for this showdown is immense and entirely justified. The game features two 23-year-old right-handers with electrifying stuff. Skenes (4-6, 1.85 ERA), the reigning NL Rookie of the Year, currently leads all of Major League Baseball in ERA. Misiorowski (2-0, 1.64 ERA), a towering 6-foot-7 rookie, began his career with an 11-inning hitless streak, the longest to start a career in modern baseball history. The radar gun will be working overtime, as Skenes averages 98.1 mph on his fastball, while Misiorowski sits at 99.7 mph and regularly tops 102.

The anticipation is so high that the game is a virtual sellout. “It’s a matchup for the ages,” said Brewers President of Business Operations Rick Schlesinger. “Two really impressive young pitchers at the top of their game.”

Mutual Respect Between Phenoms

While the competition will be fierce, there is a clear respect between the two young aces. They met on the field before the series opener to talk and pose for pictures, acknowledging the special nature of the moment.

“I think it’s going to be really entertaining to watch,” Misiorowski said. “Two guys that are at the top of their game right now. So, I think it’s cool. It’s going to be fun.”

The Supporting Cast

While the focus is on the mound, the Brewers’ offense is also red-hot. They are coming off a 9-3 victory on Tuesday, their fifth win in six games. Infielder Joey Ortiz has been a key contributor, hitting .424 during his current eight-game hitting streak. “Confidence is No. 1,” manager Pat Murphy said of Ortiz’s turnaround. “He’s starting to believe… ‘I can do some things.'” The challenge of facing such a hyped pitching matchup is a unique topic for our expert betting guide.

The Rubber Match

This epic duel will decide the series between two divisional rivals. The pitching matchup is the top story on the scores and odds board, and it’s a rare treat for fans of all MLB teams. To see who our experts think will win this historic showdown, check out our daily MLB picks.