Milwaukee Brewers vs St. Louis Cardinals June 12th 2025
The St. Louis Cardinals will take on the Milwaukee Brewers at American Family Field on Thursday, June 12, 2025. The game is set to start at 7:40 PM and will be aired on FDSMW. The weather forecast predicts mild conditions with a light breeze, but the retractable roof may limit its impact.
The Cardinals, managed by Oliver Marmol, have a 36-32 record this season. They are 5 games behind in the NL Central. On the other side, the Brewers, led by Pat Murphy, have a 36-33 record and are also 5 games back in the division. Sonny Gray will start for the Cardinals with a 7-1 record, while Jacob Misiorowski will pitch for the Brewers.
Cardinals vs Brewers Key Information
- Sport: Baseball
- Teams: St. Louis Cardinals vs. Milwaukee Brewers
- Venue: American Family Field in Milwaukee, WI
- Date: Thursday, June 12, 2025
- Betting Odds: Cardinals MoneyLine -131, Brewers MoneyLine +110
The Cardinals Can Win If…
The St. Louis Cardinals are ready to bounce back after a 2-5 loss to the Toronto Blue Jays. Willson Contreras led the team with two hits and an RBI. Yohel Pozo also contributed with a home run, showing the team’s ability to score runs even in tough games.
Despite recent setbacks, the Cardinals have strong batting stats this season. They hold the 4th best batting average at .257 and rank 3rd in doubles with 121. These stats show their potential to generate offense and put pressure on opposing pitchers.

Sonny Gray will be on the mound for the Cardinals. With a 7-1 record and a 3.35 ERA, he provides a solid chance for a win. His consistency can help the Cardinals keep the Brewers’ lineup in check and secure a victory.
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The Brewers Can Win If…
The Milwaukee Brewers are looking to bounce back after their recent 2-6 loss to the Atlanta Braves. In that game, Rhys Hoskins hit a home run, showing his power at the plate. Despite the loss, the Brewers have a lineup that can produce runs, as seen in their 4-1 win over the Braves just a day earlier.
Milwaukee’s team stats show they have strengths that can lead to a win. They rank 2nd in stolen bases with 86, which can put pressure on opposing pitchers and defenses. Their pitching staff has a respectable ERA of 3.86, placing them 15th, indicating they can limit scoring opportunities for opponents.

Key players like Rhys Hoskins and Jackson Chourio add depth to the lineup. Hoskins has 10 home runs, while Chourio has 11, providing power in the middle of the order. With Jacob Misiorowski set to start, the Brewers will aim to leverage their home-field advantage against the St. Louis Cardinals.
The Lean
The Cardinals are favored with a moneyline of -131 against the Brewers at +110. The Cardinals have a higher batting average and on-base percentage, which gives them an edge. My model projects the Cardinals to win with a score of 5-3, making them the pick for this game.
The over/under line is set at 7.5. The Cardinals’ and Brewers’ pitching stats suggest a moderate scoring game. My model projects a total score of 8 runs. Therefore, the recommendation is to take the over for this game.
Brewers Look to Future as Jacob Misiorowski Prepares for MLB Debut vs. Cardinals
Excitement is building for Milwaukee Brewers fans as top pitching prospect Jacob Misiorowski is set to make his MLB debut Thursday night when the Brewers open a four-game series against the St. Louis Cardinals.
The 23-year-old right-hander, Milwaukee’s top pitching prospect, has impressed at Triple-A Nashville, posting a 4-2 record with a 2.13 ERA across 13 games. The 6-foot-7 native of Blue Springs, Mo., now gets the call to the big leagues in a key division matchup.
“I think it just plays into the fact that the Brewers trust me, and they think I have the strength to do it,” Misiorowski said on Wednesday. “I think I’m ready and willing to do it. So, I’m excited.”
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Brewers Searching for Offensive Spark
Milwaukee enters the series looking to snap out of a recent funk. The Brewers have dropped three of their past four games and were held to just seven runs across a three-game series loss to the Atlanta Braves. Overall, Milwaukee has managed only 11 runs during its six-game homestand.
“One thing about our guys is that we’re always going to battle, but we just haven’t thrown it all together so far,” Brewers manager Pat Murphy said. “It’s not that anybody has been terrible, it just hasn’t all happened for us.”
While the offense looks to find its rhythm, the spotlight will be firmly on Misiorowski as he takes the mound Thursday.
Cardinals Looking to Reverse Recent Slide
St. Louis is also aiming to get back on track after suffering a fourth consecutive loss Wednesday, completing a sweep at the hands of the Toronto Blue Jays. During their four-game skid, the Cardinals’ pitching staff has surrendered 27 runs.
“We talked about it before the series started, this might have been one of our toughest series’ as far as matchups go,” Cardinals manager Oliver Marmol said. “Just because of the amount of contact that group makes and what we do as a pitching staff. We knew there would be challenges we’d have to navigate and (Toronto) continued to show why they’re first in the league at being the toughest to strike out.”
Since going 12-1 during a hot stretch in May, the Cardinals have gone 10-12 and currently trail the first-place Chicago Cubs by five games in the NL Central. They begin this series holding a slim half-game lead over Milwaukee.
Pitching Matchup: Misiorowski vs. Gray
Veteran right-hander Sonny Gray (7-1, 3.35 ERA) will take the mound for St. Louis, riding a dominant streak of 13 1/3 consecutive scoreless innings. Gray struck out 10 over seven shutout frames against the Texas Rangers on May 31, then followed up with 6 1/3 scoreless innings against the Dodgers on Friday.
Gray owns a 4-5 record with a 3.23 ERA in 17 career starts versus Milwaukee. In his last outing against the Brewers on April 26, he allowed three earned runs over six innings in a no-decision. St. Louis went on to win that game 6-5 on a walk-off homer by Nolan Arenado.
Thursday’s series opener not only marks an exciting debut for the Brewers’ top prospect, but also a pivotal clash in the NL Central standings. For bettors, diving into the latest MLB picks and predictions can offer an edge ahead of this marquee matchup.
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