NFL Previews 
MLB Previews 
NBA Previews 
NHL Previews 
Soccer Previews 
Prediction 
Odds 
Last Recap 
Game Picks 
Top Handicapper 
Minnesota Twins vs Arizona Diamondbacks September 12th 2025
The Arizona Diamondbacks will visit the Minnesota Twins at Target Field. Arizona holds a 73-74 record and sits fourth in the NL West. They are coming off a win and have split their last ten games. Their manager, Torey Lovullo, will look to keep the momentum going.
Get 5,000 Expert Picks for Just $9
Today Only!
Minnesota has a 64-82 record, also ranking fourth in their division, AL Central. The Twins have lost their last two games and won only two of their last ten. Rocco Baldelli, their manager, aims to turn things around at home. The game starts at 8:10 PM on Friday, September 12, 2025, and will be shown on ARID. Weather conditions are expected to be warm with overcast clouds.
Diamondbacks vs Twins Key Information
- Sport: Baseball
- Teams: Arizona Diamondbacks vs. Minnesota Twins
- Venue: Target Field in Minneapolis, MN
- Date: Friday, September 12, 2025
- Betting Odds: Diamondbacks Moneyline +110, Twins Moneyline -129, Diamondbacks Runline +1.5 (-192), Twins Runline -1.5 (+160), Total Over 8.5 (-103), Total Under 8.5 (-120)
Diamondbacks vs Twins Picks and Predictions
The Arizona Diamondbacks open a three-game road set against the Minnesota Twins in Minneapolis on Friday night. Arizona is clinging to its postseason hopes, sitting just a few games back of the Wild Card, while the Twins are looking to play spoiler down the stretch.
The Diamondbacks Can Win If…
Arizona is coming off a 5-3 win over the Giants where Eduardo Rodríguez threw 6 1/3 innings of two-hit ball. Geraldo Perdomo sparked the offense with a home run and two RBIs, while Ketel Marte, expected back in the lineup, provides much-needed consistency.
The Diamondbacks’ power has been their strength all season, ranking 5th in MLB with 199 home runs and 3rd in slugging percentage (.434). With Brandon Pfaadt (13-8, 5.18 ERA) on the mound, Arizona will need another quality start to complement its big bats like Perdomo and Christian Walker.
The Twins Can Win If…
Minnesota enters off a tough 4-3 loss to the Angels but still carries plenty of firepower. Byron Buxton homered in that game and has now hit safely in 11 of his last 12, while Trevor Larnach and James Outman add more punch to the lineup.
Pablo López takes the mound, and he’s been sharp since returning from injury. With a 2.83 ERA and 1.08 WHIP, López has the clear pitching edge. If the Twins can keep Arizona’s sluggers quiet, their own lineup ranked 10th in homers (173) has enough balance to pull out the win.
Key Stats Comparison
| Category | Diamondbacks | Twins |
|---|---|---|
| Record | 73-74 | 64-82 |
| Team ERA | 4.61 (24th) | 4.07 (13th) |
| Batting Avg. | .247 (14th) | .242 (20th) |
| Home Runs | 199 (5th) | 173 (10th) |
| Slugging % | .434 (3rd) | .407 (15th) |
Betting Odds
According to the latest MLB odds:
| Team | Moneyline | Spread | Total |
|---|---|---|---|
| Diamondbacks | +110 | +1.5 (-145) | O 8.5 (-103) |
| Twins | -129 | -1.5 (+120) | U 8.5 (-120) |
The Twins are slight home favorites with López on the mound, while the D-backs’ power gives value to their side as an underdog.
Matchup Breakdown
- Pitching Edge: López owns a 2.83 ERA compared to Pfaadt’s 5.18. Minnesota clearly has the advantage on the mound.
- Power Factor: Arizona’s 199 homers are top five in baseball, giving them the quick-strike potential to upset.
- Momentum: The D-backs have won 9 of their last 12 against Minnesota, including last season’s series.
Diamondbacks vs Twins Prediction
This matchup boils down to whether Arizona’s power can overcome López’s control. If Marte and Walker deliver early, the D-backs can grab a road win. However, the Twins’ pitching edge and Buxton’s hot bat suggest Minnesota has the upper hand.
For more daily analysis, check out our MLB expert picks and stay locked into the playoff chase.
