Minnesota Twins vs Arizona Diamondbacks Picks and Predictions September 13th 2025

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Twins’ Kody Clemens off to great start in series with Diamondbacks

Minnesota Twins (65-82) will look to ride the hot bat of Kody Clemens when they host the Arizona Diamondbacks (73-75) Saturday night at Target Field. Clemens hit three home runs in Friday’s dramatic 9-8 comeback win, giving him a career-high 19 this season.

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The Diamondbacks had a chance to steal the opener thanks to Gabriel Moreno’s three-run homer in the ninth but saw the bullpen unravel. Checking recent MLB game results, both teams have struggled for consistency, but Friday’s shootout highlighted their offensive firepower.


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Arizona Diamondbacks Can Win If…

  • Ryne Nelson stays sharp. He’s allowed just one run over his past two starts, but he’s been shelled by Minnesota in past meetings (0-2, 16.20 ERA).
  • The power bats deliver. With a team slugging percentage of .434 (3rd in MLB), Arizona needs homers from Ketel Marte, Moreno, and Geraldo Perdomo to overwhelm Joe Ryan early.
  • They shake off Friday’s collapse. The bullpen must hold leads, especially late.

“We’ve got to let ourselves cool down, get our heads about us … everybody feels terrible in that room,” Diamondbacks manager Torey Lovullo said after Friday’s loss.

Minnesota Twins Can Win If…

  • Kody Clemens stays hot. His 4-for-4, 3-HR night showed he can carry this offense when locked in.
  • Joe Ryan returns to form. The righty has a 3.32 ERA but was tagged for five runs in two innings last start. A bounce-back is critical.
  • Supporting bats contribute. Byron Buxton and Luke Keaschall provide depth — if they back Clemens, Minnesota can outslug Arizona again.

“Baseball is a crazy game … some days it looks like a beach ball,” Clemens said of his explosive Friday night.


Key MLB Betting Trends

CategoryDiamondbacksTwins
Record73-75 (4th NL West)65-82 (4th AL Central)
Last 10 Games5-53-7
Runs Per GameTop-5 slugging, 199 HRs12th in HRs, streaky bats
ERA / Opp Runs4.42 team ERA4.18 team ERA
Home/Away Record35-39 road33-41 home

The Leans

Main Pick: Twins Moneyline (-141)
Projected Final Score: Twins 5, Diamondbacks 4

  • Runline Angle: Diamondbacks +1.5 (-182) → Safer play given Arizona’s offensive upside.
  • Total Runs Angle: Over 8.5 (+100) → Both offenses showcased power Friday; Ryan and Nelson are volatile in this matchup.

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Best Bet Box

Best Bet: Twins ML (-141) + Over 8.5 (Parlay)
Confidence: ★★★★☆


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