New York Mets vs Chicago Cubs Picks and Predictions May 10th 2025

Mets vs. Cubs: A Showdown of Strengths

Saturday’s matchup between the New York Mets and Chicago Cubs sets the stage for a high-stakes clash between the National League’s top pitching staff and Major League Baseball’s most explosive offense.

Following a dominant 7-2 Mets win on Friday—powered by four home runs and Clay Holmes’ six innings of one-run pitching—Game 2 promises even more fireworks as Tylor Megill takes the mound, aiming to reverse his struggles against the Cubs.

Tylor Megill: Rising Ace with a Point to Prove

The Mets will hand the ball to right-hander Tylor Megill (3-2, 2.50 ERA), who’s been sharp this season with 45 strikeouts in seven starts and just two home runs allowed.

Yet, his track record against the Cubs raises eyebrows. In two career starts, Megill is 0-2 with a 13.50 ERA, giving up 10 earned runs in just 6 2/3 innings.

Despite the rough history, Mets manager Carlos Mendoza remains confident:

“He’s got really good stuff. He should be a guy in this league. We’re really counting on him. He needs to stay on the attack.”

For Megill, command, early strikes, and damage control will be essential against an offense that rarely misses opportunities. Check the Latest Picks from MLB Expert Handicappers

Cubs Offense: Power, Speed, and Relentless Pressure

The Chicago Cubs enter the contest as the top-scoring team in MLB with 225 runs, 349 hits, and 57 home runs. Their aggression on the basepaths is equally daunting, as they’re tied for the most stolen bases in the league (48).

Key contributors include Kyle Tucker, who leads the Cubs with 10 home runs, 32 RBIs, a .283 batting average, and a .392 on-base percentage. He also has 10 stolen bases and only 22 strikeouts. Seiya Suzuki follows closely with nine home runs and 31 RBIs, while Pete Crow-Armstrong has contributed nine home runs, 27 RBIs, and 12 stolen bases. Even veteran catcher Carson Kelly has chipped in with eight home runs and 23 RBIs, well on pace to surpass his career-best season from 2019.

Cubs Pitching: Young Blood Meets Veteran Depth

Chicago’s rotation has taken hits with injuries to Justin Steele and Shota Imanaga, pushing Brad Keller (0-0, 3.78 ERA) into a potential opener role.

More intriguing is the likely MLB debut of top prospect Cade Horton, a right-hander who’s been lights-out at Triple-A Iowa. Horton has a 2-1 record with a 1.24 ERA and 33 strikeouts in 29 innings. His velocity and command have drawn rave reviews, and the Cubs see him as a key piece for the future. But Saturday will test his nerves and skills against a potent Mets lineup.

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Mets Offense Heating Up Behind Soto-Alonso Duo

While pitching has led New York, the offense is quietly surging thanks to big names stepping up.

Juan Soto has eight home runs and 19 RBIs, including two multi-home run games this month. Pete Alonso is thriving with Soto in the lineup, boasting nine home runs, 34 RBIs, and a .324 batting average. Francisco Lindor has also been productive with eight home runs and 25 RBIs. Together, they’re forming a dangerous core that’s fueling the Mets’ recent success.

What to Watch: Key Matchups and Game Factors

One key to the game will be Tylor Megill’s ability to handle the Cubs’ top hitters—Tucker, Suzuki, and Crow-Armstrong. The debut of Cade Horton adds an element of unpredictability, especially if he can carry over his Triple-A dominance. The Mets’ offensive trio of Soto, Alonso, and Lindor will look to continue their hot streak, while the Cubs’ base-stealing capabilities could challenge the Mets’ defense.

Final Thoughts: Battle of Potential Playoff Titans

Saturday’s game is more than just a midseason clash—it’s a litmus test for both clubs. For the Mets, it’s a chance to prove their rotation can tame even the fiercest lineup. For the Cubs, it’s an opportunity to show that even without key starters, they can grind out wins with offense and emerging talent.

Whether Megill redeems himself or Horton steals the spotlight, this matchup promises drama, talent, and a glimpse at October contenders in action.