Pittsburgh Pirates vs San Francisco Giants Picks and Predictions August 5th 2025

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The San Francisco Giants will take on the Pittsburgh Pirates at PNC Park. The Giants have a record of 56-57 and are ranked third in the NL West. They are looking to bounce back from a recent loss. Their last ten games have not been great, with only two wins.

The Pirates have a record of 49-64 and are fifth in the NL Central. They have been doing well recently, winning their last two games. Their performance in the last ten games has been strong, with seven wins. Logan Webb will start for the Giants, while Mike Burrows will pitch for the Pirates. The game will be played on Tuesday, August 5, 2025, at 6:40 PM.

Giants vs Pirates Key Information

CategoryDetail
SportBaseball
MatchupSan Francisco Giants vs. Pittsburgh Pirates
VenuePNC Park, Pittsburgh, PA
DateTuesday, August 5, 2025
Giants Moneyline-156
Pirates Moneyline+133
Giants Runline-1.5 (+109)
Pirates Runline+1.5 (-130)
Total Over7.5 (+101)
Total Under7.5 (-121)

The Giants Can Win If…

The San Francisco Giants are coming off a close 5-4 loss to the Pittsburgh Pirates. Justin Verlander pitched well, allowing no earned runs over five innings. Heliot Ramos had a strong performance with three hits, showing the team’s potential at the plate.

The Giants have some solid stats that suggest they can secure a win. Their pitching staff has an ERA of 3.71, ranking 8th in the league. They have given up the fewest home runs this season, which could be key against the Pirates.

Logan Webb will start for the Giants, bringing his 3.31 ERA and nine wins to the mound. Rafael Devers, leading the team with 20 home runs, will be a key player to watch. With their strong pitching and solid hitters, the Giants have a chance to win this game.

The Pirates Can Win If…

The Pittsburgh Pirates recently played a close game against the San Francisco Giants, winning 5-4 at home. Jack Suwinski hit a home run and drove in two runs. Spencer Horwitz had a solid performance with two hits and one run scored.

The Pirates have a strong chance to win with their pitching staff. Their team ERA is 3.85, ranked 12th in the league. The Pirates’ pitchers have also been effective at limiting home runs, with only 108 given up, ranking 5th.

Offensively, the Pirates have players who can make an impact. Andrew McCutchen leads the team with 11 home runs and 39 RBIs. Spencer Horwitz has a batting average of .264 and consistently contributes to the team’s offense.

The Lean

The Giants are favored with a moneyline of -156, while the Pirates sit at +133. The Giants have a strong pitching staff with a 3.71 ERA, ranked 8th in the league. This gives them an edge over the Pirates, who have a 3.85 ERA. My model projects the Giants to win 4-3, so a straight-up pick on the Giants is recommended.

The total for the game is set at 7.5, with the over at +101 and the under at -121. Both teams have struggled offensively, with the Giants ranking 23rd in slugging percentage and the Pirates 25th. Given these stats and the projected score of 4-3, taking the under 7.5 is a solid choice.

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A Familiar Duel: Webb and Burrows Face Off Again as Pirates Host Giants

It is a night of déjà vu in Pittsburgh, a rare and immediate rematch between two talented right-handers who just locked horns less than a week ago. For the second time in six days, San Francisco’s Logan Webb and Pittsburgh’s Mike Burrows will go head-to-head on the mound. Their first duel was a classic pitcher’s battle in San Francisco, and now the scene shifts to the shores of the Allegheny River for the second act. The circumstances, however, have changed dramatically. The Pittsburgh Pirates are brimming with a newfound confidence, having dominated the season series against their opponent. The visiting San Francisco Giants are a team in transition, reeling from a tough walk-off loss and trying to find their footing after a trade deadline sell-off.

The Pirates’ Unexpected Dominance

For much of the 2025 season, the Pirates have been a team focused on the future. But for the past week, they have been a dominant force in the present, particularly against the Giants. Pittsburgh is a perfect 4-0 against San Francisco this season, a stunning record that includes a three-game sweep on the road last week. They continued that dominance in Monday night’s series opener, staging a dramatic ninth-inning comeback to earn a 5-4 walk-off victory. The win was their 10th in their last 13 games, a stretch that has seen the team play its best and most exciting baseball of the year under manager Don Kelly. The team is playing with a “nothing to lose” mentality that has made them a dangerous opponent for any team in the league.

Below is a look at the first duel between Webb and Burrows from last Wednesday, a game the Pirates ultimately won in extra innings. The official box score can be viewed in our MLB game results section.

PitcherIPHRERBBK
Logan Webb5.2511411
Mike Burrows6.031117

The Aftermath of a Sell-Off in San Francisco

While the Pirates are celebrating their recent success, the Giants are navigating the difficult reality of a rebuild. At the trade deadline, the front office made the tough decision to become “sellers,” trading away two of their best relief pitchers, Tyler Rogers and closer Camilo Doval, for future assets. The consequences of those moves were immediately felt on Monday night. Their new closer, All-Star Randy Rodriguez, was tasked with protecting a lead in the ninth inning and suffered his first blown save, a gut-wrenching moment that led to the walk-off loss.

“Usually he finishes those guys off,” a supportive but frustrated manager Bob Melvin said of his new closer. “The longer the Bart at-bat went on, typically some of those don’t go the right way… Just couldn’t finish ’em off, and that’s something Randy is as good as anybody (at) doing normally.” The volatility of a bullpen that has just lost its key pieces is a major factor for any team, a topic often explored in our expert betting guide.

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The Burrows Breakthrough and the “Unsung Hero”

A huge reason for the Pirates’ recent success has been the emergence of rookie right-hander Mike Burrows (1-3, 3.88 ERA). Burrows has been on a dominant run, with three consecutive starts of allowing two or fewer runs. He was fantastic in his last start against Webb and the Giants, allowing just one run over six strong innings. He credits much of his success to the development of his changeup, a pitch that has become a real weapon for him.

“I love using it. It’s a great pitch,” Burrows said recently. “I think it’s definitely one that’s been overlooked for the past couple years… The changeup has kind of always been there, but it’s been the unsung hero.”

Tale of the Tape: A Deeper Look at the Teams

While the Pirates have dominated the head-to-head matchups, the Giants still hold a better overall record for the season. However, the recent form of both clubs tells a different story.

TeamRecordDivision StandingRecent Form (Last 10)Run Differential
San Francisco Giants58-573rd in NL West4-6+15
Pittsburgh Pirates51-655th in NL Central8-2-55

The scores and odds for this matchup will be incredibly tight. Webb is the more established ace, but Burrows is hot, and the Pirates have had the Giants’ number all season. For more in-depth analysis of this and other games, you can view all of our MLB previews. To see who our experts are backing in this fantastic pitching rematch, check out our daily MLB picks. To get access to even more premium content and betting tools, you can register for an account today.