Pittsburgh Pirates vs San Francisco Giants Picks and Predictions August 6th 2025

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The San Francisco Giants and Pittsburgh Pirates are set to play at PNC Park. The Giants have a record of 57-57 and are third in the NL West. They have won their last game but went 3-7 in their last ten games. The Pirates, with a 49-65 record, are fifth in the NL Central. They lost their last game but have a 7-3 record over the last ten games.

Robbie Ray will start for the Giants. He has a 2.85 ERA and a 9-5 record. Andrew Heaney will pitch for the Pirates. He has a 4.89 ERA and a 5-9 record. The game will be played in the afternoon under overcast clouds with a light breeze.

Giants vs Pirates Key Information

  • Sport: Baseball
  • Teams: San Francisco Giants vs. Pittsburgh Pirates
  • Venue: PNC Park in Pittsburgh, PA
  • Date: Wednesday, August 6, 2025
  • Betting Odds: Giants Moneyline -149, Pirates Moneyline +126, Giants Runline -1.5 (+115), Pirates Runline +1.5 (-137), Total Over 7.5 (-120), Total Under 7.5 (-101)

The Giants Can Win If…

The San Francisco Giants are coming off a strong 8-1 win against the Pittsburgh Pirates. Logan Webb led the team with six innings pitched, allowing only one run and striking out ten batters. Willy Adames, Christian Koss, and Jerar Encarnacion each hit home runs, contributing to the team’s eleven hits in the game.

Key stats show the Giants’ pitching as a strength, with a team ERA of 3.68, ranking fifth in the league. They have given up the fewest home runs in the league, with only 98 allowed this season. Their ability to keep the opposition’s scoring low could be crucial in this game.

Robbie Ray will start for the Giants, boasting an ERA of 2.85 and a WHIP of 1.12. This gives the Giants a solid chance to limit the Pirates’ offense. With hitters like Rafael Devers and Willy Adames in the lineup, the Giants have the offensive firepower to support their pitching and aim for another win.

The Pirates Can Win If…

The Pittsburgh Pirates are coming off a tough 8-1 loss against the San Francisco Giants. Despite the defeat, Bryan Reynolds showed consistency at the plate, going 2-for-4 with an RBI. Jack Suwinski also contributed with a double, and Isiah Kiner-Falefa scored the only run for the Pirates.

In their recent games, the Pirates have shown they can put up runs, especially in their 9-5 win over the Colorado Rockies. Spencer Horwitz had a standout performance in that game, driving in six runs with two home runs. The Pirates have a top 10 rank in stolen bases this season, which could be a factor in creating scoring opportunities.

The Pirates’ pitching staff has been reliable, with a team ERA of 3.88, ranking 15th in the league. Andrew Heaney will take the mound, looking to improve on his 4.89 ERA. The Pirates’ ability to limit home runs, ranking 6th in the league, could be key in keeping the Giants’ offense in check.

The Lean

The Giants have a moneyline of -149, while the Pirates are at +126. Based on the data, the Giants have a stronger pitching staff with a 3.68 ERA, ranked 5th, compared to the Pirates’ 3.88 ERA, ranked 15th. My model projects the Giants to win with a score of 4-3. Therefore, the recommendation is to pick the Giants to win straight up.

The total for the game is set at 7.5 runs, with the over at -120 and the under at -101. The Giants and Pirates both rank low in slugging percentage, 24th and 27th respectively. My model projects a total score of 7 runs. Thus, the recommendation is to take the under 7.5 for this game.

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A Duel of Lefty Vets: Ray, Giants Face Heaney and the Hot Pirates in Rubber Match

It is a pivotal rubber match in Pittsburgh on Wednesday afternoon, a game that features a fantastic duel between two veteran left-handers who find themselves in very different but equally compelling situations. The visiting San Francisco Giants, a team that was a seller at the trade deadline but refuses to quit on the season, will send their All-Star ace, Robbie Ray, to the mound. He will face the host Pittsburgh Pirates and their own veteran, Andrew Heaney, who is on a personal mission of redemption after being at the center of a historic collapse in his last start.

The Giants’ Last Stand

When the Giants’ front office traded away two of their best relief pitchers at the deadline last week, it was seen as a clear signal that the team was waving the white flag on the 2025 season. The players in the clubhouse, however, have a different message: they are not done fighting. After a tough stretch, the Giants have now won three of their last five games and have clawed their way back to the .500 mark. Their 8-1 victory on Tuesday, a game in which every single batter in the lineup recorded a hit, was a powerful display of their offensive potential.

All-Star pitcher Robbie Ray perfectly encapsulated the team’s defiant mindset. “We got ourselves in this situation, but we still have the big pieces that we brought in,” Ray said on Friday. “We didn’t do a major overhaul. This team is still good enough to win.” A series victory on the road against a hot Pirates team would be a massive statement for a group that refuses to give up on its postseason hopes.

The table below provides a snapshot of two teams that, despite their different records, have been playing very good baseball in the second half of the season. To review the full box score from their last matchup, you can check the official MLB game results.

TeamRecord (2025)Recent Form (Last 10)Runs Per GameTeam ERA
San Francisco Giants60-604-64.44.15
Pittsburgh Pirates53-687-34.34.40

The Heaney Redemption Quest

While the Giants are fighting for their season, Pirates starter Andrew Heaney is fighting to erase the memory of a disastrous performance. In his last start in the high altitude of Colorado, the Pirates’ offense spotted him a massive 9-0 lead in the first inning. But Heaney was unable to hold it, lasting only 3 1/3 innings and allowing four runs as the Rockies mounted a historic comeback to win 17-16. It was a gut-wrenching experience for any pitcher, but his manager, Don Kelly, has full faith in the veteran’s ability to bounce back.

“Just watching him work every day and the way he goes about it… (seeing) the way he’s been able to bounce back from tougher outings so to speak,” Kelly said, praising Heaney’s professionalism. The psychology of a pitcher trying to rebound from a historically bad outing is a key topic for any bettor, one often explored in our expert betting guide.

The Pitching Matchup: A Deeper Look

Wednesday’s game features a fantastic duel between two of the most experienced left-handers in the National League. Ray is coming off a dominant performance against the Mets, while Heaney is looking for redemption.

PitcherW-L (2025)ERA (2025)Career vs. Opponent
Robbie Ray (SF)9-52.852-2, 4.78 ERA
Andrew Heaney (PIT)5-94.891-4, 5.84 ERA

The scores and odds for this matchup will be tight. For more in-depth analysis of this and other games, you can view all of our MLB previews. To see who our experts are backing, check out our daily MLB picks. To get access to even more premium content and betting tools, you can register for an account today.