San Diego Padres vs San Francisco Giants Picks and Predictions August 19th 2025

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Nick Pivetta Tries to Stop Padres’ Slide

The San Francisco Giants and San Diego Padres meet Tuesday night at PETCO Park for Game 2 of a four-game set. San Francisco took the opener 4-3 behind a leadoff homer from Heliot Ramos and will look to extend the Padres’ losing streak to five.

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Match Information

  • Sport: Baseball (MLB)
  • Teams: San Francisco Giants vs. San Diego Padres
  • Venue: PETCO Park, San Diego, CA
  • Date: Tuesday, August 19, 2025
  • Start Time: 9:40 PM ET
  • Broadcast: MLB.TV, RSNs

Betting Odds

  • Giants Moneyline: +193
  • Padres Moneyline: -231
  • Runline: Giants +1.5 (-115), Padres -1.5 (-104)
  • Total: 8.0 O/U (-104 / -116)

The Giants Can Win If…

Rookie Kai-Wei Teng (1-2, 9.90 ERA) finds a way to limit the damage. He was rocked for 7 runs in less than two innings against these Padres last week, but San Francisco’s path to victory comes with cleaner defense (they committed two errors Monday) and timely hitting.

Rafael Devers (23 HR, 81 RBI) remains their offensive centerpiece, while Heliot Ramos is swinging a hot bat after homering to open Monday’s win. If the Giants can scratch a few runs early and hand things to their bullpen, they can steal another road victory.

The Padres Can Win If…

Nick Pivetta (12-4, 2.87 ERA) continues his outstanding season. He dominated the Giants last week, tossing 6 2/3 innings of one-run ball in a blowout win. Pivetta is 3-1 lifetime against San Francisco and is trusted as a stopper after San Diego’s skid hit four games.

San Diego needs its bats to wake up. Manny Machado (.291, 20 HR) and Fernando Tatis Jr. (17 HR) lead the offense, while Luis Arraez (.320 AVG) remains their most consistent contact hitter. If the Padres get runners on base, their power should take care of the rest.

The key will be attacking Teng early. San Francisco’s rookie has walked too many hitters, and the Padres rank top-10 in OBP (.327). Patience at the plate could break the game open.

Key Stats Comparison

CategorySan Francisco GiantsSan Diego Padres
Record60-64 (3rd NL West)69-55 (2nd NL West)
Last 10 Games3-76-4
Runs Per Game4.1 (22nd)4.6 (8th)
Team ERA3.72 (5th)3.59 (3rd)
Opponent AVG.236 (7th).225 (1st)

The Lean

The Padres have dropped four in a row, but Nick Pivetta vs. Kai-Wei Teng is one of the biggest mismatches on the board this week. San Diego’s offense hasn’t been firing, but this is the perfect bounce-back spot against a struggling rookie.

Model Projection: Padres 5, Giants 3

  • Pick: Padres Moneyline (-231)
  • Runline Lean: Padres -1.5 (-104) for better value
  • Total Lean: Under 8.0 (-116) — both teams rank top-5 in ERA, and Pivetta should control this game

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