San Francisco Giants vs Boston Red Sox Picks and Predictions June 21st 2025

San Francisco Giants vs Boston Red Sox MLB Sat, Jun 21, 15:05 pm.
San Francisco Giants
ML: -141
0
0
Boston Red Sox
ML: 115
Last Updated on

The Boston Red Sox aim to build on Friday’s 7-5 win as they seek a second straight road victory over the San Francisco Giants. A heated opening night saw Aroldis Chapman and Wilmer Flores exchange words after Rafael Devers struck out with one out in the ninth. For a full breakdown of today’s matchups and pitching lines, check out our MLB previews.

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Devers Confronts His Former Club

Rafael Devers, facing his old team for the first time since Sunday’s blockbuster trade, went 0-for-5 and saw his average drop to .188 with the Giants after batting .272 in Boston’s first 73 games. Giants manager Bob Melvin praised Devers’ approach, insisting it’s only a matter of time before his bat breaks through. For deeper insight into how roster changes like this can sway odds, explore our expert betting guide.

Tensions Behind the Scenes

Pre-game, Red Sox skipper Alex Cora downplayed any lingering drama around the Devers trade: “It’s a baseball trade. It’s a business. For my end, I turn the page.” After the game, Chapman received a warning and a pitch-clock infraction before the exchange with Flores. If you’re looking to capitalize on late-game momentum swings, see our top MLB picks for today’s best wagers.

Starting Pitchers: Bello vs. Roupp

Boston will hand the ball to right-hander Brayan Bello (3-1, 3.49 ERA), fresh off a seven-inning shutout of the Yankees. Bello has struggled in California, posting a 6.14 ERA over four career appearances in the state. The Giants counter with righty Landen Roupp (4-5, 3.99), who allowed six runs in 1⅔ innings in his last outing. To lock in premium advice, learn how you can buy picks tailored to today’s starters.

Recent Form and Betting Outlook

Boston has won eight of its past nine games, while San Francisco has dropped five of six. That split creates value on both sides of the board. To see where the sharp money is going, consult our handicappers leaderboard and make your move with confidence.

By T. Franklin Smith | April 8, 2025
By T. Franklin Smith | April 1, 2025
spread
moneyline
over/under
San Francisco Giants
-
-
-141
O 7.5
-125
Boston Red Sox
-
-
115
U 7.5
100
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