Seattle Mariners vs Los Angeles Angels Picks and Predictions September 12th 2025

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The Los Angeles Angels will visit the Seattle Mariners at T-Mobile Park on Friday, September 12, 2025. The game is set to start at 10:10 PM and will be broadcast on APLTV. The Angels, led by manager Ron Washington, have a record of 69-77 and are ranked 4th in the AL West. They come into this game with a two-game winning streak and a 5-5 record in their last ten games.

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The Seattle Mariners, managed by Dan Wilson, have a record of 78-68 and are 2nd in the AL West. They are on a five-game winning streak and have a 6-4 record in their last ten games. The Mariners have been strong at home with a 44-27 record. The starting pitchers for this game are Yusei Kikuchi for the Angels and Luis Castillo for the Mariners. The weather forecast predicts a warm day with broken clouds.

Angels vs Mariners Key Information

  • Sport: Baseball
  • Teams: Los Angeles Angels vs. Seattle Mariners
  • Venue: T-Mobile Park in Seattle, WA
  • Date: Friday, September 12, 2025
  • Betting Odds:
    • Angels Moneyline: +144
    • Mariners Moneyline: -172
    • Angels Runline: +1.5 (-148)
    • Mariners Runline: -1.5 (+123)
    • Total Over: 7.5 (-121)
    • Total Under: 7.5 (+100)

Los Angeles Angels vs Seattle Mariners Picks and Predictions

The Los Angeles Angels head north to face the Seattle Mariners in an AL West battle with playoff implications. Seattle enters tied for first place in the division, while Los Angeles looks to play spoiler after snapping a two-game streak in their last outing.

The Angels Can Win If…

Los Angeles edged Minnesota 4-3 behind José Ureña’s steady four-inning start, while Zach Neto and Mike Trout drove in all four runs. The Angels are built on power, ranking fourth in MLB with 201 home runs.

Yusei Kikuchi (6-11, 4.18 ERA) takes the mound, looking to steady himself after recent struggles. With Jo Adell, Taylor Ward, and Trout all capable of big swings, the Angels’ best shot comes from delivering home run support and getting a serviceable outing from Kikuchi.

Angels Snapshot

CategoryStatLeague Rank
Record69-784th in AL West
Home Runs2014th
Slugging %.40712th
SP Kikuchi4.18 ERA6-11 record

The Mariners Can Win If…

Seattle stayed hot with a 4-2 win over St. Louis, led by Logan Gilbert’s eight-strikeout performance and a Leo Rivas homer. The Mariners are rolling, ranking third in homers (213) and ninth in slugging percentage (.415).

Luis Castillo (9-8, 3.85 ERA) gets the ball and has dominated the Angels historically with a 5-2 record and a sub-3.00 ERA in 10 career starts. If Castillo pitches to form and Cal Raleigh continues his league-leading home run tear, Seattle has the edge in this one.

Mariners Snapshot

CategoryStatLeague Rank
Record79-681st in AL West (tie)
Home Runs2133rd
Slugging %.4159th
SP Castillo3.85 ERA9-8 record

Key Matchups and Betting Outlook

The contrast is clear: Angels rely on big swings, while the Mariners combine power with steadier pitching. Trout’s 399th career homer snapped a drought, but can he carry L.A.’s offense against Castillo?

The Mariners are listed at -172 favorites, with the Angels at +144. The total sits at 7.5 runs. You can track movement and props live on the MLB odds board for added betting value.

Series History and Context

Seattle has now won six in a row and sits level with Houston in the AL West. The Mariners are in playoff mode already, while the Angels are looking to build around their power bats and spoil division rivals’ runs. Kikuchi faces his former team, adding extra intrigue.

Picks and Predictions

Projection: Mariners 5, Angels 3. With Castillo’s track record and Seattle’s lineup depth, the Mariners are the lean on the moneyline. The total projection of eight runs suggests value on the over 7.5 (-121).

For more daily breakdowns and betting projections, check the expert MLB picks hub.