St. Louis Cardinals vs Los Angeles Dodgers Picks and Predictions June 6th 2025

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The Los Angeles Dodgers take on the St. Louis Cardinals at Busch Stadium on Friday, June 6, 2025. The game is set for 8:15 PM and will be broadcast on SN LA. The weather forecast predicts mild conditions with overcast clouds and a calm wind.

Dodgers manager Dave Roberts leads his team with a 38-25 record this season. On the other side, Cardinals manager Oliver Marmol’s team has a 34-28 record. Justin Wrobleski will start for the Dodgers, while Sonny Gray takes the mound for the Cardinals.

Dodgers vs Cardinals Key Information

  • Sport: Baseball
  • Teams: Los Angeles Dodgers vs. St. Louis Cardinals
  • Venue: Busch Stadium in St. Louis, MO
  • Date: Friday, June 6, 2025
  • Betting Odds: Dodgers MoneyLine -111, Cardinals MoneyLine -108

The Dodgers Can Win If…

The Los Angeles Dodgers recently won a close game against the New York Mets, 6-5. Mookie Betts and Will Smith both contributed with two hits each, while Shohei Ohtani added two singles. Despite the Mets hitting three home runs, the Dodgers managed to hold on for the win.

The Dodgers lead the league with a .266 batting average and 101 home runs. Their slugging percentage of .465 is also the highest in the league. These stats show their ability to produce runs and hit for power, which can be key in winning games.

Shohei Ohtani is a standout player with a .295 average and 23 home runs. Freddie Freeman adds depth with a .363 average, and Mookie Betts is a consistent performer. With these players leading the way, the Dodgers have a strong lineup that can win games.

The Cardinals Can Win If…

The St. Louis Cardinals are coming off a tight game against the Kansas City Royals, where they lost 5-7. Nolan Arenado had a strong performance with a home run and two RBIs. Willson Contreras also contributed with two hits and three RBIs, showing his ability to drive in runs.

The Cardinals have a team batting average of .258, which ranks third in the league. This shows their ability to get on base and generate scoring opportunities. Their 113 doubles rank fourth, indicating they can hit for power and get runners into scoring position.

Sonny Gray will start for the Cardinals, bringing a solid ERA of 3.65 and a WHIP of 1.12. His record of 6-1 shows he can lead the team to victory. With Gray on the mound, the Cardinals have a strong chance to limit the Dodgers’ offense.

The Lean

The Dodgers are the pick on the moneyline at -111. They have the top-ranked batting average and slugging percentage, which gives them an edge. The model projects a score of Dodgers 5, Cardinals 4. The Dodgers’ strong hitting lineup should help them win.

For the over/under, the recommendation is to take the over at 8.5. The Dodgers’ hitting power, combined with the Cardinals’ pitching struggles, suggests a higher-scoring game. The model projects a total of 9 runs, which supports taking the over.

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Cardinals Turn to Sonny Gray in Bid to Best Dodgers

The St. Louis Cardinals will count on ace Sonny Gray (6-1, 3.65 ERA) as they host the Los Angeles Dodgers on Friday. St. Louis ranks near the bottom in total strikeouts and faces a Dodgers lineup that rarely whiffs.

Gray has been dominant recently, allowing just three earned runs over his last 19 innings. He struck out 10 and gave up only four hits in a 2-0 win over Texas last Saturday. St. Louis is eager for a strong start as they look to reset following a rough series vs Kansas City.

Stay up to date on matchups and analysis through our expert MLB picks.

Dodgers Start Wrobleski, Bolster Bullpen

The Los Angeles Dodgers will give the ball to Justin Wrobleski (1-1, 8.00 ERA), who impressed in relief earlier this month with four scoreless innings. While he’s had an inconsistent start to the season, Wrobleski still earned a win in his only career start vs the Cardinals despite giving up three home runs.

L.A. could also welcome back bullpen arms Kirby Yates and Michael Kopech this weekend after both completed rehab assignments. This could provide a key boost to a Dodgers bullpen aiming for depth on the road trip.

Check the latest MLB odds ahead of first pitch.

A baseball pitcher in a Dodgers uniform prepares to throw a pitch, showcasing his muscular build and distinctive red-accented glove.

Freeman, Edman Return; Cards Eye Reset

Freddie Freeman, the NL’s leading hitter at .363, is expected to return Friday after resting Thursday. Tommy Edman also rejoined the Dodgers lineup and could face his former club.

For deeper breakdowns and strategic insight, explore the full MLB expert betting guide. And for team-by-team performance, visit the MLB teams hub before the next pitch.

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Los Angeles Dodgers
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Mike uses his strong sports knowledge to analyze all the angles to find the most profitable wagers. Iron Mike handicaps MLB, college football, NFL, NBA, and NCAA basketball. I'm an actual sports and gambling junkie!

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