Tampa Bay Rays vs Chicago White Sox Picks and Predictions July 21st 2025

Tampa Bay Rays vs Chicago White Sox July 21st 2025

The Chicago White Sox will visit the Tampa Bay Rays at George M. Steinbrenner Field on Monday, July 21, 2025. The game is set to start at 7:35 PM and will be broadcast on FDSSU. The weather is expected to be very hot with a light breeze and overcast clouds.

The White Sox, managed by Will Venable, have a season record of 35-65. They have struggled on the road with a 14-36 record. Sean Burke will start for them, bringing an ERA of 4.36. The Rays, led by Kevin Cash, hold a 52-48 record. They have a home record of 30-26, with Shane Baz taking the mound with a 4.17 ERA.

White Sox vs Rays Key Information

• Sport: Baseball
• Teams: Chicago White Sox vs. Tampa Bay Rays
• Venue: George M. Steinbrenner Field, Tampa, FL
• Date: Monday, July 21, 2025
• Betting Odds: White Sox Moneyline +182, Rays Moneyline -218, White Sox Runline +1.5 (-112), Rays Runline -1.5 (-108), Total Over 9.0 (-101), Total Under 9.0 (-119)

The White Sox Can Win If…

The Chicago White Sox recently played against the Pittsburgh Pirates and won 7-2. Aaron Civale pitched six innings, allowing only three hits and no earned runs. Miguel Vargas and Mike Tauchman both hit home runs, contributing to the team’s strong offensive showing.

The White Sox have been on a winning streak, with three straight victories against the Pirates. They have shown strength in hitting, with extra base hits being a key factor. The team ranks 9th in doubles, which could be a game-changer against their next opponent.

Sean Burke will start on the mound for the White Sox. His ERA stands at 4.36, and he looks to build on his recent solid performances. With players like Lenyn Sosa and Luis Robert Jr. contributing, the White Sox have a good chance to continue their winning ways.

The Rays Can Win If…

The Tampa Bay Rays are coming off a narrow 5-3 loss to the Baltimore Orioles. Despite the defeat, Danny Jansen stood out with a home run and two runs scored. Yandy Díaz also had a solid performance, going 2-for-4 with a run.

The Rays have been strong at the plate this season, with a batting average of .258, ranking second in the league. Their speed on the bases is unmatched, leading the league with 129 stolen bases. This combination of hitting and speed gives them an edge in close games.

Shane Baz will take the mound for the Rays against the Chicago White Sox. With an ERA of 4.17 and a WHIP of 1.25, Baz has shown he can keep opposing hitters in check. The Rays’ ability to generate runs and Baz’s pitching could be key factors in securing a win.

Suddenly Hot White Sox Aim to Extend Streak Against Rays

The Chicago White Sox enter Monday’s matchup against the Tampa Bay Rays with rare momentum on their side — and a shot at their first four-game winning streak in more than a year.

Coming out of the All-Star break, Chicago swept the Pittsburgh Pirates in commanding fashion, including a 7-2 win Sunday to complete the team’s first road sweep in over three years. The White Sox outscored the Pirates 27-7 in the series and showed glimpses of progress despite entering the second half well out of playoff contention.

Pitcher Aaron Civale, who earned his first win since being traded to Chicago, credited the All-Star break for the team’s refreshed performance. “It’s hard to get away from this game for one day, so for a lot of guys, it’s a good reset,” Civale said. He threw six dominant innings Sunday, allowing just one unearned run with six strikeouts.

Infielder Miguel Vargas emerged as a key contributor, going 4-for-13 in the series with three doubles, a home run, and five runs scored. His three-run shot on Sunday punctuated a breakout weekend.

The White Sox (35-65) will turn to rookie right-hander Sean Burke (4-8, 4.36 ERA) in the series opener. Burke pitched five solid innings in a no-decision against the Cleveland Guardians on July 12, allowing just two runs and striking out five.

Though still 30 games under .500, Chicago is showing signs of life following a historically poor 2024 campaign that saw them finish 41-121.

Tampa Bay, meanwhile, had its own momentum slowed on Sunday in a 5-3 loss to the Baltimore Orioles, which prevented the Rays from completing a post-break sweep. Despite the setback, the Rays remain just 1.5 games out of the final American League wild-card spot and have won five of their last seven.

All-Star Junior Caminero has been red-hot, going 6-for-14 in the Baltimore series with two home runs and five RBIs. Yandy Díaz also impressed, going 6-for-10 with a homer, four RBIs and five runs scored.

Tampa will send right-hander Shane Baz (8-5, 4.17 ERA) to the mound. Baz has pitched well in his last two starts despite taking the loss in both. Most recently, he allowed just one run in 6 1/3 innings in a 1-0 loss to the Boston Red Sox on July 12.

“We still won the series,” Rays pitcher Ryan Pepiot said after Sunday’s loss. “If you win every single series, at the end of the season, you’re going to be in pretty good shape.”

At 52-48, Tampa sits fourth in the AL East, 6.5 games behind the Toronto Blue Jays. Monday’s game presents a chance to bounce back quickly and stay firmly in the postseason mix.

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The Lean

The Rays are favored with a moneyline of -218, while the White Sox are at +182. The Rays have a strong batting average, ranked 2nd in the league, and a solid pitching staff with a 3.75 ERA, ranked 10th. My model projects the Rays to win 5-3, making them the pick to win straight up.

The total for the game is set at 9.0 runs. The White Sox have struggled offensively, with a .223 batting average, ranked 21st. With both teams’ pitching being effective, my model projects a total of 8 runs. Therefore, the recommendation is to take the under at 9.0 (-119).