Toronto Blue Jays vs Minnesota Twins Picks and Predictions August 25th 2025

Last Updated on

Guerrero’s Return Adds Spark to Blue Jays as they Host Struggling Twins

The Toronto Blue Jays (76‑55) are poised to welcome All-Star first baseman Vladimir Guerrero Jr. back into the fold during their home series opener against the Minnesota Twins (59‑71). Guerrero, sidelined with a left hamstring issue, made a pinch-hit appearance Sunday, showing signs of readiness as the Jays aim to maintain their AL East lead.

sas logo

Get Inside the MLB Insiders

Access starts here

Opening Odds

  • Moneyline: Blue Jays –139 | Twins +118
  • Total (O/U): 8.0 runs (Over –106 | Under –114)

The Blue Jays Can Win If…

  • Guerrero returns strong — The All-Star (.298 with 21 HRs, 69 RBIs) brings elite presence to the lineup.
  • Max Scherzer limits damage on the mound — The veteran is solid in his starts, though he hasn’t faced the Twins since 2023.
  • Toronto’s top-tier offense keeps firing — Topping the league in batting average and OBP offers consistent production.

The Twins Can Win If…

  • Joe Ryan remains effective — Posting a 12‑6 record with a 2.96 ERA, he thrives in matchups with the Jays.
  • Offense breaks out of its slump — Twins were shut out 8‑0 Sunday despite baserunner pressure, showing frustration but potential.
  • Key hitters like Luke Keaschall and Byron Buxton drive in runs consistently, providing spark when Guerrero and company are neutralized.

Key MLB Betting Trends

CategoryBlue JaysTwins
Guerrero ReturnPotential lineup boost
Pitching MatchupScherzer vs. Ryan
Recent Form12‑9 in August2‑8 in August Seris
Offensive LeadersTop in BA & OBPKeaschall (.329 avg) and Buxton

A quick ode to how recent games are shaping division races can be seen in the latest MLB game results—a useful lens before placing your bets.

The Lean

Toronto’s offensive depth, especially with Guerrero returning, gives them a definitive edge. Scherzer’s experience anchors the hill, while Minnesota’s offense remains sputtering.

Projected Score: Blue Jays 5, Twins 3
Pick: Blue Jays Moneyline
Total Lean: Over 8.0 Runs

Explore today’s MLB Betting Tips for more insight into this matchup and beyond.