Washington Nationals vs Cincinnati Reds Picks and Predictions July 22nd 2025

Washington Nationals vs Cincinnati Reds MLB Tue, Jul 22, 17:45 pm.
Washington Nationals
ML: 110
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Cincinnati Reds
ML: -137
Last Updated on

The Cincinnati Reds will visit the Washington Nationals at Nationals Park on Tuesday, July 22, 2025. The game is set to start at 6:45 PM and will be broadcast on FDSOH. The weather forecast predicts a very hot day with clear skies and calm winds blowing out.

The Reds, managed by Terry Francona, have a season record of 52-49. They are currently 8 games back in the NL Central. The Nationals, led by interim manager Miguel Cairo, hold a 40-60 record and are 17 games back in the NL East. On the mound, the Reds will start Chase Burns, while Brad Lord will pitch for the Nationals.

Reds vs Nationals Key Information

  • Sport: Baseball
  • Teams: Cincinnati Reds vs. Washington Nationals
  • Venue: Nationals Park in Washington, DC
  • Date: Tuesday, July 22, 2025
  • Betting Odds: Reds Moneyline -135, Nationals Moneyline +115, Reds Runline -1.5 (+123), Nationals Runline +1.5 (-146), Total Over 9.0 (+101), Total Under 9.0 (-121)

The Reds Can Win If…

The Cincinnati Reds are looking to bounce back after a close 8-10 loss against the Washington Nationals. Despite the loss, Noelvi Marte and Jake Fraley had strong performances, each collecting two hits. The Reds showed they can score, putting up eight runs in the game.

The Reds have a solid batting lineup, with Elly De La Cruz leading the team in home runs and RBIs. Their team batting average of .246 ranks 12th in the league, and they have hit 107 home runs this season. The Reds’ ability to get on base and score runs gives them a good chance to win.

On the mound, the Reds will start Chase Burns, who is looking to improve his ERA of 6.19. The Reds’ pitching staff has a respectable .237 batting average against, ranking 7th in the league. If the pitching can hold the Nationals’ bats in check, the Reds have a good shot at victory.

The Nationals Can Win If…

The Washington Nationals are coming off a 10-8 win against the Cincinnati Reds. Their offense was strong, with 15 hits and 8 extra-base hits. Key players like James Wood, Josh Bell, and Brady House contributed significantly to the victory with multi-hit games.

Washington’s batting lineup shows potential for another strong performance. They have a batting average of .246, ranking 12th in the league. Their ability to hit doubles is notable, with 164 this season, placing them 10th in the league.

Starting pitcher Brad Lord could be a key factor in this game. He has a solid ERA of 3.46 and a WHIP of 1.25. With a steady performance from Lord, the Nationals have a good chance to secure another win against the Reds.

The Lean

The Reds are favored with a moneyline of -135 against the Nationals, who are at +115. Given the Nationals’ higher ERA of 5.25, ranked 28th, the Reds have a better chance to win. My model projects a score of Reds 5, Nationals 4, supporting a pick on the Reds to win.

The total for the game is set at 9.0. The Nationals’ pitching struggles, with a high ERA and batting average against, suggest runs will be scored. My model’s projected total of 9 aligns with the line, but considering both teams’ offensive and defensive stats, the over 9.0 (+101) is a reasonable pick.

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A Rookie Showcase: Chase Burns, Reds Face Lord and the Nationals

Tuesday night’s game in Washington will be a showcase for the future as two talented rookie right-handers take the mound. The visiting Cincinnati Reds will send their top prospect, Chase Burns, to the hill as they look to even their series against the Washington Nationals and their own young arm, Brad Lord.

Burns’ Breakout Performance

Reds’ top prospect Chase Burns (0-1, 6.19 ERA) is coming off the best start of his young career. In his last outing against the Rockies, the hard-throwing righty was dominant, striking out 10 batters over six strong innings of two-run ball. The only blemish was a single home run.

“He was throwing the ball extremely aggressively,” Reds manager David Bell said of Burns’ last start. “Other than that, he was terrific.”

A man, likely a baseball player, is seen from the mid-chest up. He is wearing a red baseball cap with a white design, and a red and white baseball team jersey.

Lord’s Second Chance

The Nationals will counter with right-hander Brad Lord (2-5, 3.46 ERA), who is getting a second chance to prove himself in the starting rotation. After starting the season in the bullpen, Lord made six starts before returning to a relief role. Now, with injuries piling up, he gets another opportunity.

“I definitely think it will be easier this time around,” Lord said. “I’ve already done it once, so (I will) take what I learned from that into this.”

Washington’s Offensive Awakening

The Nationals’ offense, which has struggled for much of the season, exploded in the series opener for a 10-8 victory. They pounded out 15 hits and eight walks, with veterans like Josh Bell and young players like Brady House and James Wood all having big nights. “Those were good at-bats today,” said interim manager Miguel Cairo. “We kept going, and we put good at-bats together. It was beautiful.” This matchup of a hot offense against a hot young pitcher is a key topic in our expert betting guide.

This duel between two promising rookies will be a key focus on the scores and odds board. For two MLB teams focused on their rebuilds, these are the kinds of matchups that provide a glimpse into the future. To see which rookie our experts think will shine, check out our daily MLB picks.