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The DePaul Blue Demons travel to Omaha with a rare opportunity in their sights: a season sweep of the Creighton Bluejays. This Big East battle is set for Wednesday, February 25, 2026, at 9:00 PM ET at the CHI Health Center Omaha. After DePaul snapped a 23-game losing streak against the Bluejays earlier this month, the rematch shifts to Creighton’s home turf, with the game streaming live on PEAC.
Creighton (14-14, 8-9 Big East) enters the matchup as a 5.5-point favorite. Despite an inconsistent season, the Bluejays remain formidable at home with an 11-5 record. DePaul (14-13, 6-10 Big East) is currently the +190 underdog on the moneyline, looking to overcome a difficult 2-7 road record and prove that their one-point victory on February 11 was no fluke. The total for this contest is set at 142.5 points.
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DePaul vs. Creighton Odds
Bettors should monitor the lines leading up to tipoff, as Big East conference games often see movement based on shooting trends and frontcourt availability.
| Team | Moneyline | Spread | Total |
| DePaul Blue Demons | +190 | +5.5 (-117) | O 142.5 (-110) |
| Creighton Bluejays | -246 | -5.5 (-109) | U 142.5 (-110) |
DePaul Blue Demons Betting Form
The Blue Demons are led by the surging NJ Benson, who has been statistically elite over his last three games. Benson is averaging nearly 20 points and shooting a staggering 64.0% from the floor this season. In the previous meeting with Creighton, he dominated with 23 points on 10-of-11 shooting. When Benson and CJ Gunn (14.0 PPG) are clicking, DePaul’s offense can challenge the top half of the Big East.
Historically, DePaul has been a strong bet as an underdog this season, covering the spread in 60% of those contests. However, they must clean up their peripheral play; a recent loss to Providence was defined by a poor 50% performance from the free-throw line and a -10 rebounding margin. For a deeper look at their seasonal trends, visit the DePaul stats and results.
Creighton Bluejays Betting Form
Creighton is looking to regain their footing after a Jekyll-and-Hyde week that saw them upset No. 5 UConn only to be blown out by 29 points against St. John’s. The Bluejays’ offense relies heavily on the perimeter, ranking 60th nationally with 9.9 made three-pointers per game. Josh Dix leads a balanced attack with 12.1 PPG, and the team boasts an effective field goal percentage of 53.8%.
The Bluejays have been a reliable pick when favored at home, winning 10 of 14 games in that position. Coach Greg McDermott’s squad is focused on 40 minutes of discipline after “letting the ball roll” in the final seconds of their previous loss to DePaul. To track their home dominance and offensive efficiency, visit the Creighton schedule and stats.
DePaul vs. Creighton Matchup Breakdown
This game will be decided in the paint and at the arc. DePaul’s NJ Benson is the “red-hot” factor; if Creighton cannot find a way to push him off his spots, the Blue Demons can stay within a single possession. However, Creighton’s offensive ceiling is significantly higher when they are playing at the CHI Health Center Omaha, where their shooting percentages tend to spike.
DePaul head coach Chris Holtmann has noted the “little separation” in the middle of the Big East standings. With both teams fighting for seeding in the upcoming conference tournament, expect a high-intensity battle where rebounding becomes the X-factor. Creighton’s ability to space the floor with nearly 10 threes per game puts immense pressure on DePaul’s perimeter defense.
- NJ Benson (DePaul): 25-of-29 FG shooting over the last three games.
- Creighton Home Record: 11-5
- Previous Meeting: DePaul 72, Creighton 71 (Feb 11)
- 3-Point Shooting: Creighton averages 9.9 made per game.
DePaul vs. Creighton Predictions and Best Bets
While DePaul has the individual talent to keep this close, Creighton at -5.5 is the lean here. The Bluejays are 11-5 at home and are coming off an embarrassing loss, which typically leads to a focused, high-energy performance in the following game. Our model projects a final score of 75-72 in favor of Creighton, but the Bluejays’ superior 3-point shooting and home efficiency should allow them to stretch the lead just enough to cover the two-possession spread.
For the total, the Over 142.5 is the recommended play. Both teams are averaging a combined 147 points per game, and with NJ Benson scoring at a career-high rate and Creighton’s high-volume shooting, this game has all the markings of a high-scoring conference tilt.
Best Bet: Creighton -5.5 (-109)
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