Georgetown Hoyas vs Depaul Blue Demons Picks and Predictions January 28th 2026

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DePaul Blue Demons vs Georgetown Hoyas Picks and Predictions – Wednesday January 28, 2026

DePaul heads to Washington, D.C. on Wednesday night trying to turn a solid Big East home profile into something that travels. The Blue Demons are 4-1 in league play at home, but still sitting on zero conference road wins, and that’s the next box they have to check if this rebuild is going to keep gaining traction.

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Georgetown has been all over the place, but it finally got a result that can change the tone. The Hoyas snapped a six-game skid with a comeback win at Providence, and now they’re back at Capital One Arena with a short number as the favorite. That’s a tricky spot, because DePaul has won four straight in this series and already beat Georgetown 56-50 earlier this month by completely choking off the Hoyas after halftime.

From a betting standpoint, this sets up as a classic clash between “home court plus momentum” and “matchup problems plus series results.” I’m more interested in the possession-by-possession edges than the narratives.

DePaul Blue Demons vs Georgetown Hoyas Odds

These are the current lines, but make sure you’re tracking the latest college basketball odds in case the spread or total moves off key numbers before tip.

TeamMoneylineSpreadTotal
DePaul Blue Demons+163+4.5 (-113)140.5
Georgetown Hoyas-204-4.5 (-113)140.5

DePaul Blue Demons Betting Form

DePaul’s best basketball has come when it can dictate physicality and turn games into half-court reps. They’ve been better at getting to the line than most teams in this range, and that matters as a road dog because it keeps you scoring when the jumper goes cold. It also keeps the favorite from getting clean runouts after misses.

The concern is obvious: conference road games have been a problem. When DePaul’s offense loses structure, the shot quality drops fast, and that’s when margins get ugly. If they’re going to cover here, they need to avoid empty possessions, keep their defensive rebounding clean, and get the game into the low 60s or low 70s in total possessions.

The other key angle is confidence in the defensive game plan. In the first meeting, DePaul’s second-half defense was dominant, and that type of schematic edge tends to travel if the focus is there.

Georgetown Hoyas Betting Form

Georgetown’s ceiling is tied to shot creation and getting to the foul line. The comeback at Providence showed the Hoyas can ramp up pressure and scoring pace when they have to, but the larger sample says they’ve struggled to sustain stops and string together efficient halves against league competition.

At home, the Hoyas are simply more comfortable. They play with better energy early, and the role players usually give them a little more juice. That matters in a spot like this, because DePaul’s biggest weakness is letting the game slip for a five-minute stretch on the road. Georgetown does not need to dominate for 40 minutes to cover. It needs one good run plus enough defensive possessions to keep DePaul from living at the stripe.

This is also a bounce-back matchup stylistically. Georgetown already saw what DePaul wants to do to them, and you should expect better spacing, more purposeful early offense, and fewer “walk it up and hope” possessions.

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DePaul Blue Demons vs Georgetown Hoyas Matchup Breakdown

This handicap starts with pace and control. DePaul is fine playing ugly if it’s organized ugly. Georgetown would rather get the game moving, create early offense, and lean into free throws when DePaul starts reaching. If the Hoyas succeed in speeding this up, the spread becomes more reasonable.

The second layer is shot quality. DePaul is more likely to win the possession battle with free throws and defensive rebounding. Georgetown is more likely to win it by forcing DePaul into tough jumpers and turning those misses into transition chances. The first meeting points to DePaul being able to take away Georgetown’s comfort looks, but Georgetown should also have counters ready after seeing that film.

Late-game execution matters with this number. If it’s a one or two possession game inside four minutes, I trust the underdog with the points, even if Georgetown is the better late-shot-making team. DePaul doesn’t need to finish. It needs to stay connected.

DePaul Blue Demons vs Georgetown Hoyas Predictions and Best Bets

I lean DePaul +4.5. The matchup has already shown DePaul can drag Georgetown into a low-efficiency game, and as a road dog, that’s the profile I want. Georgetown’s home edge is real, but the number is asking the Hoyas to win by multiple possessions against a team that has played them well for two seasons.

The total lean is under 140.5, mostly because DePaul’s best cover script is slower and more physical, and Georgetown’s worst offensive stretches come when they’re forced to execute late in the clock. The risk to the under is a foul-heavy game, because both teams can turn free throws into points without needing clean shooting.

If I’m picking one bet, I’d rather take the points than guess the whistle. DePaul’s floor is higher as a dog if the pace stays reasonable, and this is a tight number where one cold Georgetown stretch can do the job.

Best Bet: DePaul +4.5

NCAAB Picks and Handicappers on ScoresAndStats

If you’re betting Wednesday’s board, start with the full slate on college basketball picks and compare where consensus sits versus where the best long-run performers are leaning on the best handicappers page. I also like checking the handicappers leaderboard to see who’s seeing the market well right now, not just who’s had a good week.

For more matchup coverage and quick reads, the NCAAB previews hub keeps everything in one place, and the college basketball teams hub helps when you’re bouncing between recent form and schedule spots. If you want broader betting angles beyond a single game, the ScoresAndStats blog is useful, and the Expert Betting Guide is a good process check when you’re tightening your approach.

If you’re shopping outs or comparing operators, sportsbook reviews can help, and if you’re evaluating premium services, handicappers sites reviews is the clean place to start. When you want to scale up and follow a paid card, you can also buy picks.

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