Iowa State Cyclones vs Oklahoma State Cowboys Picks and Predictions January 10th 2026

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The Iowa State Cyclones enter 15-0 and look to extend their program-best start, while the Oklahoma State Cowboys aim to build on their bounce-back win in this Big 12 clash at Hilton Coliseum.

Line Movement and Odds

Iowa State opened as the favorite, with the line reflecting confidence in their unbeaten record and defensive consistency. Current market:

  • Iowa State Spread: -8.5 (-110)
  • Oklahoma State Spread: +8.5 (-110)
  • Iowa State MoneyLine: -360
  • Oklahoma State MoneyLine: +290
  • Total: 142.5 (-110)

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Matchup Breakdown

Iowa State Outlook

Iowa State averages 79.6 points per game, with Joshua Jefferson, Tamin Lipsey, and Milan Momcilovic leading the offense. Jefferson’s double-double vs Baylor (19 points, 17 rebounds) highlighted his impact, while Lipsey’s playmaking (14.8 ppg, 5.6 apg) adds balance. Their defensive intensity and ability to adjust at halftime have fueled their unbeaten run. Their 15-0 overall record and 2-0 Big 12 mark underscore dominance.

Oklahoma State Outlook

Oklahoma State averages 77.4 points per game, with Parsa Fallah, Kanye Clary, and Christian Coleman providing scoring depth. Fallah’s 24 points vs UCF and Clary’s breakout (18 points, 9 rebounds, 8 assists) highlight offensive potential. Their 13-2 overall record and 1-1 Big 12 mark underscore competitiveness, though defensive lapses against Texas Tech showed vulnerability. Coleman’s status (flu) remains key for their frontcourt presence.

Key Matchup / Path to Victory

The game hinges on Iowa State’s ability to maintain defensive intensity and rebounding dominance, while Oklahoma State must lean on Fallah and Clary to pace the offense. If Iowa State controls tempo and perimeter defense, their depth should create separation. Oklahoma State’s hopes rest on improved shooting and Coleman’s availability.

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Injuries / Availability

Iowa State: No injuries reported.

Oklahoma State: Christian Coleman (flu) questionable. No other notable injuries listed.

Environment

Hilton Coliseum provides Iowa State with a strong home-court edge, where they have thrived during their unbeaten run. Oklahoma State’s balanced offense highlights their ability to compete in Ames despite road challenges.

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Best Bets and Prediction

Projected Final Score: Iowa State 76, Oklahoma State 67

  • Iowa State -8.5 → Best Bet. Their defensive consistency and rebounding edge make them the sharper side.
  • Under 142.5 → Total play. Both teams’ defensive adjustments point toward a combined score below the line.

Iowa State’s depth and defensive intensity should dictate the game, while Oklahoma State’s offense keeps the spread in play. Expect a competitive contest trending under the total.

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