St. John’s Red Storm vs Depaul Blue Demons Picks and Predictions December 16th 2025

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St. John’s Red Storm (6-3) host the DePaul Blue Demons (8-3) on Tuesday night in New York. Both teams enter Big East play with renewed defensive focus, aiming to build momentum in their conference opener.

Line Movement and Odds

  • St. John’s Red Storm Spread: -7.5
  • DePaul Blue Demons Spread: +7.5
  • St. John’s Red Storm MoneyLine: -310
  • DePaul Blue Demons MoneyLine: +245
  • Total: 142.5

St. John’s opened as a solid favorite, reflecting their home-court advantage and recent defensive improvements. DePaul’s strong finish to nonconference play has kept bettors interested, but oddsmakers expect St. John’s depth to prevail. The total of 142.5 points suggests expectations for a moderately paced contest, shaped by both teams’ defensive emphasis. See updated numbers and market shifts on the College Basketball Odds page.

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Matchup Breakdown

St. John’s Red Storm Outlook

The Red Storm defeated Iona 91-64, holding an opponent to its fewest points for the second straight game. Coach Rick Pitino emphasized defensive growth after early-season struggles, noting last year’s team also improved dramatically after December. Bryce Hopkins leads with 14.9 points per game, while Zuby Ejiofor adds 14.4 points, 7.2 rebounds, and 2.7 blocks. St. John’s has six double-digit scorers, showcasing balanced offense to complement their defensive resurgence.

DePaul Blue Demons Outlook

The Blue Demons edged Wichita State 61-58 after rallying from a 16-2 deficit, holding the Shockers to 33.3% shooting the rest of the way. Coach Chris Holtmann praised the team’s defensive growth, noting back-to-back season-low points allowed. CJ Gunn leads with 14.2 points per game, while NJ Benson adds 6.5 rebounds and RJ Smith contributes 10 points per game. DePaul averages 74.8 points per game and has shown improved shooting efficiency, hitting 51.1% from the floor and 41.2% from three in their last outing.

Key Matchup / Path to Victory

St. John’s balanced scoring and interior defense versus DePaul’s perimeter shooting is the focal battle. The Red Storm must continue their defensive discipline, while the Blue Demons rely on Gunn’s scoring and Benson’s rebounding to stay competitive.

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Injuries / Availability

St. John’s: Full roster available.
DePaul: Full roster available.

  • St. John’s has held opponents under 65 points in consecutive games.
  • Ejiofor leads the Red Storm in rebounds, assists, and blocks.
  • DePaul has won three of its last four games.
  • Gunn leads DePaul with 14.2 points per game.
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Best Bets and Prediction

Projected Final Score: St. John’s 74, DePaul 66

  • Pick: St. John’s -7.5. The Red Storm’s defensive resurgence and depth should allow them to cover at home.
  • Total: Under 142.5. Both teams’ defensive emphasis points to a lower-scoring outcome.

Expect St. John’s to continue its defensive turnaround, with Hopkins and Ejiofor leading the way, while DePaul’s improved shooting keeps the game competitive.

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