Villanova Wildcats vs Pennsylvania Quakers Picks and Predictions December 6th 2025

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The Villanova Wildcats face the Pennsylvania Quakers in the Big 5 Championship title game in Philadelphia. Villanova (6-1) enters on a six-game winning streak, while Penn (5-3) looks to rebound after a loss to Hofstra. Bettors must weigh Villanova’s depth and momentum against Penn’s balanced scoring and resilience.

Line Movement and Odds

  • Villanova Wildcats Spread: -12.5 (-110)
  • Pennsylvania Quakers Spread: +12.5 (-110)
  • Villanova Wildcats MoneyLine: -800
  • Pennsylvania Quakers MoneyLine: +550
  • Total: 141.5 (Over -110, Under -110)

Villanova opened as strong favorites in this city rivalry. See full NCAA Basketball odds for market movement.

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Matchup Breakdown

Villanova Wildcats Outlook

Villanova has won six straight since a season-opening loss to BYU. Tyler Perkins scored 19 points and Duke Brennan added 14 points and 8 rebounds in their win over Temple. The Wildcats average 74 points per game and rely on balanced scoring and rebounding. Coach Kevin Willard emphasizes the importance of learning to win meaningful games, making this championship clash a key test.

Pennsylvania Quakers Outlook

Penn advanced to the title game with wins over Saint Joseph’s and Drexel but fell to Hofstra 77-60. Ethan Roberts leads with 16 points per game, while Michael Zanoni adds scoring depth. The Quakers average 70 points per game but shot just 32% in their last outing. Coach Fran McCaffrey highlighted fatigue as a factor, but Penn’s balanced attack can still challenge Villanova.

Key Matchup / Path to Victory

Villanova’s depth vs Penn’s perimeter shooting. The Wildcats must rely on Perkins and Brennan to control tempo, while Penn needs Roberts and Zanoni to spark offense and avoid shooting slumps.

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Injuries / Availability

Villanova: No major injuries reported, Perkins and Brennan lead the lineup.
Penn: No major injuries reported, Roberts and Zanoni expected to anchor scoring.

  • Villanova is 6-1 overall, with six straight wins.
  • Villanova averages 74 points per game.
  • Penn is 5-3 overall, with a recent loss to Hofstra.
  • Penn averages 70 points per game but struggles with shooting consistency.
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Best Bets and Prediction

Projected Final Score: Villanova 76, Penn 64

  • Villanova -12.5 (-110) → Best Bet. Wildcats’ momentum and depth suggest they cover.
  • Under 141.5 (-110) → Total. Our model projects 140 points, leaning under given Penn’s shooting struggles.

Villanova’s balanced attack and winning streak should secure the Big 5 crown, while Penn’s inconsistency makes them unlikely to keep pace. Expect Villanova to cover with the total trending under.

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