Wake Forest Demon Deacons vs Vanderbilt Commodores Picks and Predictions December 21st 2025

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The Wake Forest Demon Deacons enter 9-3 and look to secure a signature non-conference win, while the Vanderbilt Commodores aim to remain undefeated at 11-0. Bettors will weigh Vanderbilt’s offensive firepower against Wake Forest’s home-court edge in this matchup at Lawrence Joel Coliseum.

Line Movement and Odds

Vanderbilt opened as a slight favorite, with the line reflecting confidence in their unbeaten record. Current market:

  • Vanderbilt Spread: -4.5 (-113)
  • Wake Forest Spread: +4.5 (-111)
  • Vanderbilt MoneyLine: -206
  • Wake Forest MoneyLine: +165
  • Total: 160.5 (-110)

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Matchup Breakdown

Vanderbilt Outlook

Vanderbilt averages 93.7 points per game, with Duke Miles and Tyler Tanner leading the offense. Their shooting efficiency (58.1% effective FG) and perimeter game (10.6 threes per game) highlight strengths. Their 11-0 record and recent overtime win over Memphis underscore resilience and betting confidence.

Wake Forest Outlook

Wake Forest averages 85.3 points per game with Juke Harris and Myles Colvin providing scoring depth. Their rebounding and pace (71.6 possessions per game) highlight balance. Their 9-3 record and strong 7-3 home mark underscore competitiveness, though their narrow win over Longwood shows inconsistency.

Key Matchup / Path to Victory

The game hinges on Vanderbilt’s ability to maintain offensive rhythm, while Wake Forest must lean on Harris to pace the offense. If Vanderbilt controls tempo and boards, their depth should create separation, but Wake Forest’s home-court advantage could keep the margin tight.

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Injuries / Availability

Vanderbilt: No confirmed injury updates available. You can check each team’s injury report for the latest status.

Wake Forest: No confirmed injury updates available. You can check each team’s injury report for the latest status.

Environment

Lawrence Joel Coliseum provides Wake Forest with a strong home-court edge, where they are 7-3 this season. Vanderbilt’s unbeaten record highlights their ability to perform under pressure.

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Best Bets and Prediction

Projected Final Score: Vanderbilt 88, Wake Forest 82

  • Vanderbilt -4.5 → Best Bet. Their offensive pace and efficiency make them the sharper side.
  • Over 160.5 → Total play. Both teams’ scoring averages point toward a combined score above the line.

Vanderbilt’s depth and shooting should dictate the game. Expect the Commodores to cover, while the total trends over due to both teams’ offensive pace.

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