Xavier Musketeers vs Creighton Bluejays Picks and Predictions December 17th 2025

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Xavier opens Big East play riding a five-game winning streak and looking increasingly comfortable on both ends of the floor. The Musketeers sit at 8-3 and have won six of their last seven, with ball movement and perimeter efficiency driving the surge. You can track updated pricing and movement on the NCAA basketball odds page as conference play tips off.

Tre Carroll continues to set the tone. He leads Xavier at 16.9 points per game while shooting nearly 40 percent from three. Xavier shares the ball as well as any team in the league, leading the Big East in assists and ranking near the top in three-point accuracy. That connectivity has translated into cleaner possessions and fewer empty trips.

Creighton enters at 5-5 and searching for answers after a difficult nonconference stretch. The Bluejays have dropped multiple games against elite competition and arrive off back-to-back losses to Nebraska and Kansas State. Greg McDermott acknowledged the need for reflection as Creighton works to rediscover its offensive rhythm.

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Line Movement and Odds

Xavier opens as the home favorite, supported by recent form and efficiency trends. Creighton’s struggles on offense have pulled the total lower than preseason expectations for this matchup. Bettors are weighing Xavier’s ball security against Creighton’s ability to generate enough clean looks to keep pace.

For a broader view of conference matchups and projections, see the college basketball previews page.

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Matchup Breakdown

Xavier’s advantage lies in execution. The Musketeers move the ball, space the floor, and convert from deep. When Carroll draws attention, others benefit, and Xavier’s assist numbers reflect that balance. Limiting turnovers has been a major factor in their recent run.

Creighton’s offense has not looked like itself. The Bluejays average under 75 points per game and have only one double-digit scorer in Josh Dix. Shot quality and tempo have been inconsistent, and defensive stops have not translated into easy offense. If Creighton stays competitive, it likely comes from slowing Xavier’s pace and forcing contested jumpers.

For consensus leans and supporting angles, the free college basketball picks section helps frame expectations.

Injuries and Conditions

Xavier

No new injuries reported.
Full details: Xavier team page

Creighton

No new injuries reported.
Full details: Creighton team page

Indoor matchup, no weather considerations.

Best Bets and Prediction

Xavier’s current form, ball movement, and perimeter shooting give them a clear edge at home. Creighton’s offensive efficiency needs a jump to keep pace in this spot.

Projected Score: Xavier 78, Creighton 70
Best Bet: Xavier ATS
Secondary Lean: Under, tied to Creighton’s offensive inconsistency

For matchup-based betting fundamentals and situational angles, use the Bettors Handbook.

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