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Clemson vs Florida State Week 11 Betting Preview
Clemson and Florida State have dominated the ACC for more than a decade, winning 13 of the past 14 conference titles. On Saturday in South Carolina, they’re both fighting to stay bowl-eligible.
The Tigers (3-5, 2-4 ACC) began the season ranked No. 4 but have fallen apart, losing 46-45 to Duke last week. The Seminoles (4-4, 1-4) ended a four-game slide with a 42-7 rout of Wake Forest.
Clemson coach Dabo Swinney called the Duke loss “very frustrating,” and with his defence allowing 24 points per game — 10th in the ACC — the pressure is on to respond.
You can compare current lines and totals for this matchup on the NCAA football odds board before kickoff.
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Line Movement and Odds
Clemson opened around a 2.5-point favorite, but sharp bettors have hit Florida State early in the week. The Tigers remain slight home favorites, with the total holding near 56.
Public money leans toward Clemson, though many models now show value on the Seminoles against the spread. For a full odds snapshot across multiple books, see the latest college football picks
Matchup Breakdown
Clemson’s defence has slipped badly under new coordinator Tom Allen. The unit allowed 158 yards in the fourth quarter alone last week and has been vulnerable to explosive plays.
Florida State’s offence has been the opposite — fast, vertical, and productive. The Seminoles lead all Power Four teams with 18 plays of 40+ yards. Receiver Duce Robinson has topped 140 yards in three games and ranks among ACC leaders in yards per catch.
The trenches will decide this one. Clemson’s front must contain FSU’s balanced run game or risk getting burned deep again. For a deeper statistical view of both programs, check their team pages
Injuries and Conditions
Clemson:
- QB Cade Klubnik (ankle) – expected to play.
- WR Bryant Wesco Jr. (back) – out for season.
- OL E. Ware (shoulder) – out.
Florida State:
- WR Jayvan Boggs – out.
- LB Stefon Thompson – questionable.
Review full updates on the Clemson injury report and Florida State injury report
Weather in Clemson should be clear and mild, around 60°F, with little wind — no impact on the passing game.
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Best Bets and Prediction
Clemson is 0-5 ATS in its past five. Florida State is 1-4 ATS but found momentum last week. The Seminoles’ speed advantage and big-play edge should carry weight.
Prediction: Florida State 28, Clemson 24
Best Bet: Florida State +2.5
Lean: Under 56
Get more analysis in the expert betting guide and track premium handicappers on the leaderboard. For guaranteed plays, visit the Service Plays page, or explore our NCAA football previews
