Indiana Hoosiers vs Oregon Ducks Betting Preview
Indiana Hoosiers enter the Peach Bowl ranked #1, riding a 14-0 season led by Heisman winner Fernando Mendoza. Oregon Ducks stand at 13-1, ranked #5, powered by QB Dante Moore and a balanced offense. This CFP semifinal in Atlanta sets up a rematch of their October clash, won by Indiana 30-20.
Line Movement and Odds
Indiana opened as a -4 favorite, with market support steady. Public lean favors the Hoosiers’ undefeated run, but Oregon’s ATS record as an underdog has drawn sharp interest.
- Indiana Spread: -4.0 (-111)
- Oregon Spread: +4.0 (-110)
- Indiana MoneyLine: -186
- Oregon MoneyLine: +154
- Total: 47.5 (-110)
For broader market context, check the latest college football odds page.
Matchup Breakdown
Indiana Outlook
QB Fernando Mendoza leads the Hoosiers with 3,172 passing yards and 36 touchdowns, supported by RB Roman Hemby’s 1,007 rushing yards. Indiana ranks top-five nationally in scoring and rushing, while their defense adds 39 sacks and 18 interceptions. Their ability to sustain drives and pressure quarterbacks provides a path to victory.
Oregon Outlook
QB Dante Moore headlines the Ducks with 3,280 passing yards and 28 touchdowns, supported by RB Noah Whittington’s 774 rushing yards. Oregon ranks top-15 nationally in scoring and rushing, while their defense adds 22 sacks and 13 interceptions. Their balanced offense and defensive resilience are critical to covering the spread.
Key Matchup / Path to Victory
The game hinges on Indiana’s passing efficiency against Oregon’s secondary. If Mendoza establishes rhythm early, Indiana controls tempo. Oregon must lean on Moore’s playmaking and defensive disruption to stay inside the number.
Injuries / Availability
Indiana lists DB Bryson Bonds and DL Kellan Wyatt out, while RB Lee Beebe Jr. is sidelined.
Oregon has WR Kyler Kasper and OL Bryce Boulton out, while WR Evan Stewart is questionable.
Environment
Mercedes-Benz Stadium provides a neutral-site setting, though Indiana’s fan base has traveled strongly throughout the CFP. Oregon’s resilience and Indiana’s undefeated run add intrigue. Weather conditions indoors keep execution clean.
Best Bets and Prediction
Projected Final Score: Indiana 24, Oregon 21
- Oregon +4.0 → Best Bet. Strong ATS record as underdog and balanced offense give them cover potential.
- Under 47.5 → Playable. Both defenses rank top-20 nationally, pointing to a lower-scoring contest.
Expect a competitive game with Indiana’s efficiency providing the difference, but Oregon’s resilience keeping it close. The projected score supports the underdog cover and a lean to the under.
Handicappers and Service Plays
For bettors tracking this semifinal, our Best Handicappers page highlights expert records and current streaks, while the Leaderboard shows who’s been most consistent through bowl season. Premium Buy Picks deliver matchup-specific service plays, ATS angles, and totals analysis. Whether you prefer consensus trends or contrarian strategies, these resources provide sharper context for navigating one of the most anticipated CFP semifinals.


